HydroxypropypropinyL methylcelllulose (HPMC) ke e sebelisoang haholo indastering ea lik'hemik'hale tse fapaneng ka lebaka la sebopeho sa eona se ikhethang sa lik'hemik'hale.
1. Likhatiso tsa lik'hemik'hale:
a. Moutulose Oa Khutla:
HPMC ke sesebelisoa se hlahisoang ke celluulose, ho bolelang hore e nkiloe le Cellloulose, Polysaccharide e fumanehang marakong a lily. Celllolose e na le likarolo tsa li-unit tsa β-D-glucose e hokahantsoeng ke Β (1 → 4) maqhama a glycsidic.
b. Sebaka:
Ho HPMC, hydroxyl (-oh) ka lebaka la ho hlonepha ha mokokotlo oa sele celluune ho nkeloa ka lihlopha tsa methyl le tsa hydroxyl. Karolo ena e etsahala ka karabelo ea motlakase. Degree of Singlution (DS) e bua ka palo ea li-hydroxyl ka lihlopha tsa Glucose tsa Glucose ka ketane ea celluko. Li-DS tsa Lihlopheng tsa Methyl le Hydroping li fapane, tse amang tšebetso ea HPMC.
2. Synthesis:
a. Phapanyetsano:
HPMC e kenella ka mokhoa oa menyetla ea celluulose ea nang le ponts'o ea poplene oxide le methyl chloride. Ts'ebetso ena e kenyelletsa ho etsa qhobolase e nang le oxide ea ho ngola ho hlahisa lihlopha tsa hydroxypropyl ebe u hlahisa lihlopha tsa methyl ho hlahisa lihlopha.
b. Tekanyo ea taolo e itseng:
DS ea HPMC e ka laoloa ka ho fetola maemo a ho etsa lintho tse kang mocheso, nako ea ho phela le pelehi le pelehi.
3. Ts'ebetso:
a. Fulle:
HPMC e qhibilisoa ka metsing le li-kalvenic li-solvent tse kang methanol le ethanol. Leha ho le joalo, kutloano ea eona e fokotseha ka boima ba li-sour tsa molek'hule le degree.
b. Sebopeho sa lifilimi:
HPMC e theha filimi e pepeneneng le e bonolo ha e qhibiliha ka metsing. Lifilimi tsena li na le thepa e ntle ea matla le litlokotsebe.
C. Viscosity:
HPMC tharollo e hlompheha boits'oaro ba pseudorial, bo bolelang hore litšoantšiso tsa bona li fokotsa ka sekhahla se ntseng se eketseha. Litaba tsa tharollo ea HPMC li itšetlehile ka lintho tse kang tse hlonehang, boima ba bomo-kholo le degree.
d. Ho Boloka Metsi:
E 'ngoe ea thepa ea bohlokoa ea HPMC ke bokhoni ba eona ba ho boloka metsi. Letlotlo lena le lefella likopakeng tse fapaneng joalo ka lisebelisoa tsa kaho, moo HPMC e sebelisoa e le moemeli oa metsi le metsi.
e. Pherekano:
HPMC hangata e sebelisoa e le khokahano indastering e fapaneng ka lebaka la bokhoni ba eona ba ho theha maqhama a matla a supe.
4. TLHOKOMELISO:
a. Indasteri ea meriana:
Li-Pharmaceutical, HPMC e sebelisoa e le moqapi oa moemeli, moemeli oa baesekele ea lifilimi, le moemeli ea laoloang oa ho rekisoa, le modifoli oa lipampiri.
b. Indasteri ea kaho:
HPMC e eketsoa ka lilakane tse thehiloeng ho saense, lipampiri tse thehiloeng ho sayeng, le lik'haseto tsa gyps tse thehiloeng ho ntlafatsa ho ntlafatsa, ho boloka metsi le ho boloka moea.
C. indasteri ea lijo:
Indastering ea lijo, HPMC e sebelisoa e le bolotsana, e hlolloang le e moqomo e tsoang ho liso tsa leshano, liaparo le ice cream.
d. Lihlahisoa tsa tlhokomelo ea motho:
HPMC e sebelisoa e le molora oa thickener, emmolifier le lifilimi li etsa lihlahisoa tsa tlhokomelo e kang shampoos, lithaba le litlolo.
e. Paints le Likotsi:
Ka lipente le makhapetla, HPMC e sebelisoa ho ntlafatsa ho hasaha ha likolobe, taolo ea liphio le ho boloka metsi.
HydropxypropitypropityPyLithpropyLuloseth (HPMC) ke tšebeliso e fapaneng ea likopo tse fapaneng ho indasteri e fapaneng. Sebopeho sa eona sa lik'hemik'hale tse ikhethang tsa lik'hemik'hale, Syntthesis le thepa e e etsa motsoako oa bohlokoa ho meriana, thepa ea kaho, lijo / boea. Ho utloisisa thepa ea HPMC ho lumella likopo tse netefalitsoeng ka har'a likarolo tse fapaneng, li tlatselletsa ho sebelisoa ka mokhoa o fapaneng le tsa bohlokoa mererong ea sejoale-joale.
Ka mor'a nako: Hlakubele 22-2024