Tšimong ea meriana, sodium carboxemethylcellulose (HYDROYXY FYTHCEPING EA LITLHAKISO TSA BOPHELO LE LITLHAKISO TSE KHOLO.
Sebopeho sa lik'hemik'hale le thepa
CMC ke molaoli oa liluluble tsa metsi tse fumanoeng ka ho fetola likarolo tsa lihlopha tsa hydroyl tsa celdroyl Tekanyetso ea metsi le pono ea cmc e itšetlehile ka boima ba eona le boima ba limoleke, 'me hangata e itšoara joaloka moemeli ea motle le ea emisang.
HPMC e fumanoa ka ho nkela karolo ea lihlopha tsa hydroxyl tse nang le celdulese le lihlopha tsa hydroxypropyl. Ha ho bapisoa le CMC, HPMC e na le lisosa tse pharaletseng, li ka qhibiliha metsing a batang le a chesang, 'me a bonts'a pono e tsitsitseng ea boleng bo fapaneng PH. HPMC hangata e sebelisoa e le filimi ea pele, e khomaretsoeng, e lehljherener le e laoloang ke li-pharmatucaucal.
Tšimo ea Kopo
Matlapa
Tlalehong ea matlapa, cmc e sebelisoa e le sefokotsi le ho khomarela. E le ho senyeha, cmc e ka monya metsi le ruruna, ka tsela ea ho khothaletsa sekhahla sa matlapa le ho eketsa sekhahla sa lithethefatsi. Joaloka binder, cmc e ka ntlafatsa matla a mochini oa matlapa.
HPMC e sebelisoa haholo e le moemeli oa pele ebile o laoloa ke moemeli oa tokollo litafoleng. Filimi e thehileng ke HPMC e na le matla a matle le ho roala hararo, e ka sirelletsang moriti maemong a tikoloho ea kantle. Ka nako e ts'oanang, thepa e etsang mofuta oa hpmc e ka sebelisoa ho laola sekhahla sa ho lokolloa hoa moriana. Ka ho lokisa mofuta le litekanyetso tsa HPMC, sephetho se tsitsitseng se ka fihlellehang.
Li-capsules
Ho itokisetsa, CMC ha e sebelisoe, ha HPMC e sebelisoa haholo, haholo ho hlahiseng likuku tsa limela. Likhetla tsa moetlo oa Choplule li entsoe ka gelatin, empa ka lebaka la bothata ba mehloli ea liphoofolo, HPMC e fetohile thepa e ntle e loketseng. Khefutso ea Caplule e entsoeng ka HPMC ha e na puo ea biocompatication hantle, empa hape e kopana le litlhoko tsa limela.
Litokisetso tsa metsi
Due to its excellent thickening and suspension properties, CMC is widely used in liquid preparations such as oral solutions, eye drops and topical preparations. CMC e ka eketsa pono ea litokisetso tsa metsi, ka ho etsa joalo o ntlafatsa lithethefatsi le ho thibela lithethefatsi tsa lithethefatsi.
Ts'ebeliso ea HPMC ka litokisetso tsa metsi e le tse ling haholo ka thipa le emulusifurs. HPMC e ka lula e tsitsitse ho pH ea phallo e ngata ebile e ka lumellana le mefuta e fapaneng ea lithethefatsi ntle le ho ama katleho ea lithethefatsi. Ntle le moo, thepa e etsang lifilimi ea hpmc e sebelisoa le litokisetso tsa holimo, joalo ka phello e sebelisang phello ea limpho ka marotholi a leihlo.
Litokisetso tse laoloang
Litokisetso tse laoloang, tšebeliso ea HPMC e hlahile haholo. HPMC e khona ho theha netweke ea lehare la li-gel, le sekhahla sa ho lokolloa ha moriana o ka laoloa ka ho fetola khatello le sebopeho sa HPMC. Thepa ena e sebelisitsoe haholo ka matlapeng a lokollotsoeng ka molomo le litšusumetso. Ho fapana le moo, cmc ha e sebelisoe litokisetsong tse laoloang - haholo hobane sebopeho sa gel se hlahisa mefuta ha e tsitsitse joalo ka HPMC.
Ho tsitsa le ho lumellana
CMC e na le botsitso bo fokolang ba boleng bo fapaneng ba pH mme bo angoa habonolo ke libaka tsa acid. Ntle le moo, CMC e tsamaisana hampe ka lisebelisoa tse itseng tsa lithethefatsi, tse ka etsang hore motho a hlōle lithethefatsi kapa a hloleha ho hloleha ho hloleha ho hloleha.
HPMC e bontša ho tsitsipalla ka boholo ba phallo e pharaletseng, ha e amehe habonolo ke acid-setsi, 'me e na le monyetla o motle haholo. HPMC e ka lumellana le metsoako e mengata ea lithethefatsi ntle le ho ama botsitso le katleho ea lithethefatsi.
Polokeho le melaoana
Ka bobeli cmc le hpmc li nkoa e le tse sireletsehileng tsa phaello se sireletsehileng sa meriana le tse amohetseng bakeng sa ho sebelisoa litokisetsong tsa meriana tsa meriana linaheng tse fapaneng. Leha ho le joalo, nakong ea tšebeliso, CMC e ka etsa hore lintho tse ling tse kulang kapa tse sa thabiseng haholo, ha HPMC ha e baka mokhoa o fosahetseng.
Cmc le hpmc ba na le melemo ea bona ho Promacecontatic. CMC e lula maemong a bohlokoa litokisetsong tsa metsi ka lebaka la lits'ebeletso tsa eona tse ntle tsa ho holisa le ho emisoa, ha HPMC li sebelisoa haholo litafole le litokisetso tse laoloang ke filimi. Khetho ea litokisetso tsa meriana e lokela ho ipapisitse le thepa e itseng ea lithethefatsi le litlhoko tsa ho itokisetsa, ho bala melemo le likotsi tsa batho ka bobeli le ho khetha tse loketseng haholo.
Nako ea poso: Jul-19-2024