Hydroxyethyl cellulose (HEC) ke polima e se nang ionic, e qhibilihang ka metsing e tsoang ho selulose. E sebelisoa haholo liindastering tse fapaneng, ho kenyeletsoa li-adhesives, moo e sebetsang e le ntho e teteaneng, rheology modifier, le stabilizer. Bokhoni ba HEC ba ho ntlafatsa viscosity ea likhomaretsi bo bohlokoa bakeng sa lits'ebetso tse ngata, ho netefatsa ts'ebeliso e nepahetseng, ts'ebetso le nako e telele ea sehlahisoa sa sekhomaretsi.
Thepa ea Hydroxyethyl Cellulose
HEC e hlahisoa ka ho arabela cellulose ka ethylene oxide tlas'a maemo a alkaline, e leng se hlahisang polymer e nang le lihlopha tsa hydroxyethyl tse khomaretsoeng mokokotlong oa cellulose. Tekanyo ea ho fetola (DS) le molar substitution (MS) ke likarolo tsa bohlokoa tse susumetsang thepa ea HEC. DS e bua ka palo e tloaelehileng ea lihlopha tsa hydroxyl ho molek'hule oa selulose tse nketsoeng sebaka ke lihlopha tsa hydroxyethyl, ha MS e bontša palo e tloaelehileng ea li-moles tsa ethylene oxide tse ileng tsa arabela ka mole e le 'ngoe ea li-unit tsa anhydroglucose ka selulose.
HEC e khetholloa ka ho qhibiliha ha eona metsing, ho etsa litharollo tse hlakileng le tse hlakileng tse nang le viscosity e phahameng. Viscosity ea eona e susumetsoa ke lintlha tse 'maloa, ho kenyelletsa boima ba limolek'hule, mahloriso, mocheso le pH ea tharollo. Boima ba molek'hule ba HEC bo ka tloha ho tlase ho ea holimo haholo, ho lumella ho etsoa ha li-adhesives tse nang le litlhoko tse sa tšoaneng tsa viscosity.
Mekhoa ea Ntlafatso ea Viscosity
Hydration le ho ruruha:
HEC e ntlafatsa viscosity ea sekhomaretsi haholo-holo ka bokhoni ba eona ba ho nosetsa le ho ruruha ka metsing. Ha HEC e eketsoa ka mokhoa oa ho khomarela metsi, lihlopha tsa hydroxyethyl li hohela limolek'hule tsa metsi, tse lebisang ho ruruha ha liketane tsa polymer. Ho ruruha hona ho eketsa khanyetso ea tharollo ho phalla, ka hona ho eketsa viscosity ea eona. Tekanyo ea ho ruruha le viscosity e hlahisoang e susumetsoa ke mahloriso a polymer le boima ba limolek'hule tsa HEC.
Khokahano ea Molek'hule:
Ka tharollo, li-polymers tsa HEC li kenella ka lebaka la sebopeho sa tsona sa ketane e telele. Ho kopanngoa hona ho etsa marang-rang a sitisang ho tsamaea ha limolek'hule ka har'a sekhomaretsi, kahoo ho eketsa viscosity. Boima bo phahameng ba limolek'hule HEC e fella ka ho ts'oaroa ha bohlokoa le ho ba le viscosity e phahameng. Tekanyo ea ho ts'oaroa e ka laoloa ka ho lokisa mahloriso a polymer le boima ba molek'hule ba HEC e sebelisitsoeng.
Hydrogen Bonding:
HEC e ka theha maqhama a haedrojene ka limolek'hule tsa metsi le likarolo tse ling molemong oa sekhomaretsi. Litlamo tsena tsa hydrogen li kenya letsoho ho viscosity ka ho theha marang-rang a hlophisitsoeng haholoanyane ka har'a tharollo. Lihlopha tsa hydroxyethyl mokokotlong oa cellulose li ntlafatsa bokhoni ba ho theha li-bond tsa haedrojene, ho eketsa viscosity.
Boitšoaro ba ho Thinning:
HEC e bonts'a boitšoaro ba ho kuta, ho bolelang hore viscosity ea eona e fokotseha tlas'a khatello ea ho kuta. Thepa ena e na le molemo lits'ebetsong tsa sekhomaretsi hobane e lumella ho sebelisoa habonolo tlas'a ho kuta (joalo ka ho hasa kapa ho brushing) ha u ntse u boloka viscosity e phahameng ha u phomotse, ho netefatsa ts'ebetso e ntle ea sekhomaretsi le botsitso. Boitšoaro ba ho kuta moriri oa HEC bo bakoa ke ho lumellana ha liketane tsa polymer ka tataiso ea matla a sebelisoang, ho fokotsa ho hanyetsa ka hare ka nakoana.
Likopo ho Liqapi tsa Sekhomaretsi
Likhomaretsi tse Thehiloeng ka Metsi:
HEC e sebelisoa haholo likhomaretsing tse thehiloeng metsing, tse kang tsa pampiri, masela le lehong. Bokhoni ba eona ba ho tiisa le ho tsitsisa sebopeho sa sekhomaretsi se tiisa hore se lula se kopane ka mokhoa o ts'oanang 'me se le bonolo ho se sebelisa. Likhomaretsing tsa pampiri le tsa ho paka, HEC e fana ka viscosity e hlokahalang bakeng sa kopo e nepahetseng le matla a tlamahano.
Likhomaretsi tsa kaho:
Likhomaretsing tsa kaho, tse kang tse sebelisetsoang ho kenya lithaele kapa likoahelo tsa marako, HEC e ntlafatsa viscosity, e ntlafatsa ho sebetsa ha sekhomaretsi le ho hanyetsa ho senyeha. Ketso e teteaneng ea HEC e tiisa hore sekhomaretsi se lula se le teng nakong ea kopo mme se beha hantle, se fana ka tlamo e matla le e tšoarellang.
Likhomaretsi tsa Litlolo le Tlhokomelo ea Motho:
HEC e boetse e sebelisoa lihlahisoa tsa litlolo le tsa botho tse hlokang thepa ea sekhomaretsi, joalo ka li-gels tsa setaele sa moriri le limaske tsa sefahleho. Lits'ebetsong tsena, HEC e fana ka ts'ebetso e bonolo le e ts'oanang, e matlafatsang ts'ebetso ea sehlahisoa le boiphihlelo ba mosebelisi.
Likhomaretsi tsa Meriana:
Indastering ea meriana, HEC e sebelisoa lipacheng tsa transdermal le lits'ebetsong tse ling tsa phepelo ea lithethefatsi moo viscosity e laoloang e leng bohlokoa bakeng sa ts'ebetso ea sekhomaretsi. HEC e tiisa hore lera la sekhomaretsi le tšoana, le fana ka phepelo e tsitsitseng ea lithethefatsi le ho khomarela letlalo.
Lintlha tse Amang Ntlafatso ea Viscosity
Tsepamiso ea maikutlo:
Motsoako oa HEC ka mokhoa oa ho khomarela o lekana ka ho toba le viscosity. Maemo a phahameng a HEC a fella ka ho eketseha ha viscosity ka lebaka la litšebelisano tsa bohlokoa tsa ketane ea polymer le ho ts'oaroa. Leha ho le joalo, ho tsepamisa mohopolo ho feteletseng ho ka lebisa ho gelation le bothata ba ho sebetsa.
Boima ba Molek'hule:
Boima ba limolek'hule tsa HEC ke ntlha ea bohlokoa ho khethollang viscosity ea sekhomaretsi. Boima bo phahameng ba limolek'hule HEC e fana ka viscosity e phahameng maemong a tlase ha e bapisoa le mefuta e tlase ea boima ba limolek'hule. Khetho ea boima ba limolek'hule e itšetlehile ka viscosity e lakatsehang le litlhoko tsa kopo.
Mocheso:
Mocheso o ama viscosity ea tharollo ea HEC. Ha mocheso o ntse o eketseha, viscosity hangata e fokotseha ka lebaka la ho fokotseha ha maqhama a hydrogen le ho eketseha ha limolek'hule tsa motsamao. Ho utloisisa kamano ea mocheso le viscosity ho bohlokoa bakeng sa lits'ebetso tse pepesehetseng mocheso o fapaneng.
pH:
PH ea sebopeho sa sekhomaretsi se ka susumetsa viscosity ea HEC. HEC e tsitsitse ho feta mefuta e mengata ea pH, empa maemo a pH a feteletseng a ka lebisa liphetohong tsa sebopeho sa polymer le viscosity. Ho etsa li-adhesives ka har'a mofuta o nepahetseng oa pH ho netefatsa ts'ebetso e tsitsitseng.
Melemo ea ho sebelisa Hydroxyethyl Cellulose
Tlhaho eo e seng ea Ionic:
Sebopeho se seng sa ionic sa HEC se etsa hore e lumellane le mefuta e mengata ea likarolo tse ling tsa tlhahiso, ho kenyelletsa le li-polymers tse ling, li-surfactants le li-electrolyte. Ho lumellana hona ho lumella libopeho tse fapaneng tsa sekhomaretsi.
Biodegradability:
HEC e tsoa ho cellulose, mohloli oa tlhaho le o ka nchafatsoang. E na le biodegradable, e leng se etsang hore e be khetho e ntle ea tikoloho bakeng sa metsoako ea sekhomaretsi. Tšebeliso ea eona e tsamaisana le tlhoko e ntseng e hola ea lihlahisoa tse tšoarellang le tse bonolo ho eco.
Botsitso:
HEC e fana ka botsitso bo babatsehang ho metsoako ea sekhomaretsi, ho thibela ho arohana ha mekhahlelo le ho lokisa likarolo tse tiileng. Botsitso bona bo tiisa hore sekhomaretsi se lula se sebetsa nakong eohle ea bophelo ba eona le nakong ea kopo.
Lintho tsa ho Etsa Lifilimi:
HEC e etsa lifilimi tse feto-fetohang le tse hlakileng ha li omisoa, tse molemo bakeng sa lisebelisoa tsa sekhomaretsi tse hlokang mohala o hlakileng le o bonolo oa bond. Thepa ena e bohlokoa haholo lits'ebetsong tse kang lileibole le litheipi.
Hydroxyethyl cellulose e bapala karolo ea bohlokoa ho ntlafatseng viscosity ea likhomaretsi ka mekhoa e joalo ka hydration le ho ruruha, ho ts'oaroa ha limolek'hule, bonding ba hydrogen, le boits'oaro ba ho kuta. Thepa ea eona, ho kenyelletsa ho qhibiliha, tlhaho e seng ea ionic, biodegradability, le bokhoni ba ho etsa lifilimi, e e etsa khetho e nepahetseng bakeng sa lits'ebetso tse fapaneng tsa sekhomaretsi. Ho utloisisa lintlha tse amang ntlafatso ea viscosity ea HEC, tse kang ho tsepamisa mohopolo, boima ba molek'hule, mocheso le pH, ho lumella baetsi ba lihlahisoa ho etsa lihlahisoa tsa sekhomaretsi ho finyella litlhoko tse khethehileng tsa tshebetso. Ha liindasteri li ntse li tsoela pele ho batla lisebelisoa tse tsitsitseng le tse sebetsang hantle, HEC e ntse e le karolo ea bohlokoa ha ho etsoa lihlahisoa tse tsoetseng pele tsa sekhomaretsi.
Nako ea poso: May-29-2024