HPMC e sebelisa litlhare tsa pharmaceuta

HydroxypropypropypropinyL methyl cellularse (HPMC) e sebelisoa haholo indastering ea meriana bakeng sa lits'ebetso tse fapaneng, ka lebaka la thepa ea eona e arohaneng. Mona ke tšebeliso ea bohlokoa ea HPMC ho meriana:

1. Ho koaloa ha tafole

1.1 karolo ea lifilimi tsa lifilimi

• Filimi e theha: HPMC e sebelisoa hangata e le moemeli ea etsang lifilimi ka har'a letlapa. E fana ka moholi o mosesaane, o ts'oanang le o sirelletsang holim'a leqhubu le matla, ho ntlafatsa, botsitso le boiketlo ba ho koenya.

1.2 Coating

• Tšireletso: Lihloohong tse ling, HPMC e sebelisoa ka har'a likotla tse lokisehileng, tse sirelletsang lesiti ho asiti, lumella ho lokolloa ha lithethefatsi mala.

2. Metsoako e laoloang e laoloang

2.1 Khopolo-kholo

• Thuso e laoloang ea lithethefatsi: HPMC e sebetsa mekhoeng e lokollotsoeng ho laola sekhahla sa ho lokolloa ha sethethefatsi ka nako e telele, ho fella ka phello ea nako e telele.

3. Liphoso tsa molomo le li-suppenrantes

3.1 Moemeli oa Thickening

• Thickening: HPMC e sebelisoa e le moemeli oa ho holisa ka lino tse nang le molomo.

4. Tharollo ea mahlo

4.1 Moemeli oa ho etsa mobricating

• Lubrication: Litharollo tsa mahlo, HPMC ke moemeli oa libilione, o ntlafatsang phello e hlakileng sefahlehong le khothatso.

5. Litokisetso tsa holimo

5.1 Formation ea Gel

• Moetlo oa Gel: HPMC e sebelisoa ho sebopeho sa li-geseletso tsa leqephe, ho fana ka thepa e lakatsehang ea rheology ea rheological e lakatsehang le ho ruta esita le ka ho ajoa ke motsoako o sebetsang.

6. Matlapa a qhibilihang (odt)

6.1 ntlafatso ea phetoho

• Ho qhalana: HPMC e sebelisoa ho thekeng ea matlapa a ho ntlafatsa ka molomo ho ntlafatsa mathata a bona a ho se tšepahale, ho lumella ho felisoa kapele ka molomo.

7. Li-drops tsa leihlo le li-cooki

Tsamaiso ea Litšoantšiso tsa 7.1

• Ntlafatso ea liketsahalo: HPMC e sebelisetsoa ho laola pono ea li-drops tsa mahlo le likarolo tse tsoekere, li thibela kopo e nepahetseng ebe e boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebetso e nepahetseng le ho boloka ts'ebeliso e nepahetseng le ho boloka ts'ebetso e nepahetseng le ho boloka tšebeliso e nepahetseng.

8. LITLHAKISO LE LITLHAKISO

8.1 Litekanyetso

• Taolo ea Litekanyetso: Kakaretso ea HPMC e lokela ho hlahlojoa ka hloko ho fihlela thepa e lakatsehang ntle le tšusumetso e sa sebetseng hantle ntle le tšusumetso e ntle e sa sebetseng hantle ntle le tšusumetso e ntle e sa sebetseng hantle ntle le tšusumetso e ntle e sa sebetseng hantle ntle le tšusumetso e ntle e sa sebetseng hantle.

Katleho

• Ho lumellana: HPMC e lokela ho lumellana le metsoako e meng ea merima, ho ba tsebiso le metsoako e sebetsang ho netefatsa botsitso le katleho.

8.3 Ho lumellana ha litlhare

• Mehopolo ea likhahla: Litlhaloso tse nang le HPMC li tlameha ho latela litekanyetso tsa taolo le litataiso ho netefatsa polokeho le katleho.

9. Qeto

HydroxypropypropypropypropypropyLe Methyl, e eketsoa ka bongata indastering ea methapo ea methapo ea methapo, e kenyang lithapelo, litokisetso tsa mahlo, le tse ling. Mechini ea eona e etsang lifilimi, ho holisa le ho lokolla ha taolo e laoleheng ho etsa hore e be e bohlokoa likolong tse fapaneng tsa meriana. Ho nahanela ka hloko ha ho hlahlobisisa litekanyetso, ho lumellana le litlhoko tse laoloang ke tsa bohlokoa bakeng sa lihlahisoa tse sebetsang le tse lumellanang le li-ramisang.