Hydroxypropyl methyl cellulose le carboxymethyl cellulose sodium li ka tsoakoa
Hydroxypropyl methyl cellulose (HPMC) le carboxymethyl cellulose sodium (CMC) ke lintho tse peli tse tsoang ho cellulose tse sebelisoang haholo liindastering tse fapaneng ka lebaka la thepa ea tsona e ikhethang le ts'ebetso ea tsona. Le ha ka bobeli e le li-polymers tse thehiloeng ho cellulose, li fapana ka sebopeho sa tsona sa lik'hemik'hale le thepa, e li etsang hore li tšoanelehe bakeng sa lits'ebetso tse fapaneng. Leha ho le joalo, maemong a mang, li ka tsoakoa ho fihlela litšoaneleho tse itseng tsa ts'ebetso kapa ho ntlafatsa thepa e itseng ea sehlahisoa sa ho qetela.
Hydroxypropyl methyl cellulose (HPMC), e tsejoang hape e le hypromellose, ke selulose e seng ea ionic e tsoang ho cellulose ea tlhaho ea polymer. E entsoe ka karabelo ea alkali cellulose ka propylene oxide le methyl chloride. HPMC e sebelisoa haholo litlhare, thepa ea kaho, lihlahisoa tsa lijo, le litlolo ka lebaka la thepa ea eona e ntle haholo ea ho etsa lifilimi, ho tenya, ho tlama le ho boloka metsi. HPMC e fumaneha ka limaraka tse fapaneng ka maemo a fapaneng a viscosity, e lumellang tšebeliso ea eona mefuteng e mengata ea lits'ebetso.
Ka lehlakoreng le leng, carboxymethyl cellulose sodium (CMC) ke motsoako oa anionic cellulose o qhibilihang ka metsing o fumanoang ke karabelo ea cellulose ka sodium hydroxide le chloroacetic acid. CMC e tsejoa ka matla a eona a phahameng a ho boloka metsi, bokhoni ba ho tenya, thepa ea ho etsa lifilimi, le botsitso maemong a fapaneng a pH. E fumana lits'ebetso lihlahisoa tsa lijo, meriana, litlolo, masela le tlhahiso ea pampiri ka lebaka la ho ikamahanya le maemo le ho lumellana ha eona.
Leha HPMC le CMC li arolelana thepa e 'ngoe e tloaelehileng joalo ka ho qhibiliha ha metsi le bokhoni ba ho etsa lifilimi, li bonts'a litšobotsi tse ikhethang tse li etsang hore li tšoanelehe bakeng sa lits'ebetso tse ikhethileng. Ka mohlala, HPMC e ratoa mekhoeng ea meriana e kang matlapa le li-capsules ka lebaka la thepa ea eona e laoloang-ho lokolloa le ho lumellana le metsoako e sebetsang ea meriana. Ka lehlakoreng le leng, CMC e atisa ho sebelisoa lihlahisoa tsa lijo tse kang li-sauces, liaparo le lintho tse halikiloeng e le ntho e matlafatsang le e tsitsitseng.
Leha ho na le liphapang tsa tsona, HPMC le CMC li ka tsoakoa hammoho mekhoeng e itseng ho fihlela litlamorao tsa synergistic kapa ho ntlafatsa thepa e itseng. Ho tsamaellana ha HPMC le CMC ho ipapisitse le lintlha tse 'maloa joalo ka sebopeho sa tsona sa lik'hemik'hale, boima ba limolek'hule, tekanyo ea ho fetola, le thepa e lakatsehang ea sehlahisoa sa ho qetela. Ha li kopantsoe hammoho, HPMC le CMC li ka bonts'a thepa e ntlafetseng ea botenya, e tlamang le ea ho etsa lifilimi ha e bapisoa le ho sebelisa polymer feela.
Tšebeliso e le 'ngoe e tloaelehileng ea ho kopanya HPMC le CMC ke ho theha mekhoa ea ho fana ka lithethefatsi e thehiloeng ho hydrogel. Li-Hydrogel ke mekhoa ea marang-rang e nang le mahlakore a mararo e khonang ho monya le ho boloka metsi a mangata, e leng se etsang hore e tšoanelehe bakeng sa lisebelisoa tse laoloang tsa tokollo ea lithethefatsi. Ka ho kopanya HPMC le CMC ka likarohano tse nepahetseng, bafuputsi ba ka hlophisa thepa ea hydrogel joalo ka boitšoaro ba ho ruruha, matla a mochini, le kinetics ea ho lokolla lithethefatsi ho fihlela litlhoko tse ikhethileng.
Tšebeliso e 'ngoe ea ho kopanya HPMC le CMC ke ho lokisa lipente le lipente tse thehiloeng metsing. HPMC le CMC hangata li sebelisoa e le li-thickeners le rheology modifiers lipenteng tse thehiloeng metsing ho ntlafatsa thepa ea tsona ea kopo, joalo ka brushability, sag resistance, le spatter resistance. Ka ho lokisa karo-karolelano ea HPMC ho CMC, baetsi ba lihlahisoa ba ka finyella viscosity e lakatsehang le boitšoaro ba ho phalla ha pente ha ba ntse ba boloka botsitso le ts'ebetso ea eona ka nako.
Ntle le meriana le liphahlo, metsoako ea HPMC le CMC e boetse e sebelisoa indastering ea lijo ho ntlafatsa sebopeho, botsitso le molomo oa lihlahisoa tse fapaneng tsa lijo. Mohlala, HPMC le CMC hangata li eketsoa lihlahisoa tsa lebese tse kang yogurt le ice cream e le li-stabilizers ho thibela karohano ea mekhahlelo le ho ntlafatsa botlolo. Linthong tse halikiloeng, HPMC le CMC li ka sebelisoa e le li-conditioner tsa hlama ho ntlafatsa thepa ea ho tšoara hlama le ho eketsa nako ea bophelo.
ha hydroxypropyl methyl cellulose (HPMC) le carboxymethyl cellulose sodium (CMC) e le li-derivatives tse peli tse ikhethang tsa selulose tse nang le thepa le lits'ebetso tse ikhethang, li ka tsoakoa hammoho ka mekhoa e itseng ho fihlela litlamorao tsa synergistic kapa ho ntlafatsa thepa e itseng. Ho lumellana ha HPMC le CMC ho ipapisitse le lintlha tse fapaneng joalo ka sebopeho sa bona sa lik'hemik'hale, boima ba limolek'hule, le thepa e lakatsehang ea sehlahisoa sa ho qetela. Ka ho khetha ka hloko karo-karolelano le motsoako oa HPMC le CMC, baetsi ba lihlahisoa ba ka hlophisa thepa ea lihlahisoa tsa bona ho fihlela litlhoko tse khethehileng tsa meriana, litlolo, lihlahisoa tsa lijo, le liindasteri tse ling.
Nako ea poso: Apr-12-2024