Hydroxypropyl methylcellulose (HPMC) ke non-ionic metsi-qhibilihang selulose ether sebelisoa haholo kahong, meriana, lijo, litlolo le lik'hemik'hale. Litšobotsi tsa viscosity tsa tharollo ea eona ea metsi ke lintlha tsa bohlokoa tse amang ts'ebetso ea ts'ebeliso ea eona.
1. Litšobotsi tsa motheo tsa HPMC
AnxinCel®HPMC ke motsoako oa cellulose o entsoeng ka ho hlahisa lihlopha tsa hydroxypropyl le methyl ka har'a ketane ea limolek'hule ea selulose. E na le ho qhibiliha ha metsi hantle le viscosity e batlang e le holimo, 'me hangata e sebelisoa ho lokisa litharollo tsa metsi tse nang le thepa e khethehileng ea rheological. Litšobotsi tsena li etsa hore HPMC e sebelisoe haholo ho lira, likhomaretsi, tokollo e tsitsitseng ea lithethefatsi, li-additives tsa lijo le liindasteri tse ling.
2. Litšobotsi tsa viscosity tsa tharollo ea metsi a HPMC
Litšobotsi tsa viscosity tsa tharollo ea metsi ea HPMC li angoa ke lintlha tse ngata, haholo-holo ho kenyelletsa mahloriso, mocheso, sekhahla sa ho kuta, boleng ba pH le sebopeho sa limolek'hule.
Phello ea mahloriso ho viscosity
The viscosity ea HPMC aqueous solution e eketseha ka mahloriso a ntseng a eketseha. Ha mahloriso a HPMC a le tlaase, tharollo e nang le metsi e tšesaane ebile e na le viscosity e tlaase; ha mahloriso a ntse a eketseha, ho sebelisana pakeng tsa limolek'hule ho eketseha, 'me viscosity ea tharollo ea metsi e eketseha haholo. Ka tloaelo, viscosity ea tharollo ea HPMC e amana ka mokhoa o hlakileng le mahloriso a eona, empa e atisa ho tsitsa ka mokhoa o itseng, ho bontša litšobotsi tsa viscosity tsa tharollo.
Phello ea mocheso ho viscosity
Mocheso ke ntlha ea bohlokoa e amang viscosity ea AnxinCel®HPMC aqueous solution. Ha mocheso o ntse o phahama, likamano tsa hydrogen le litšebelisano tsa hydrophobic ka limolek'hule tsa HPMC li tla fokola, e leng se fellang ka ho fokotseha ha matla a tlamang pakeng tsa limolek'hule, kahoo ho fokotsa viscosity ea tharollo ea metsi. Ka kakaretso, viscosity ea tharollo ea metsi ea HPMC e bonts'a mokhoa o moholo oa ho theoha ka mocheso o ntseng o eketseha, haholo maemong a phahameng a mocheso. Tšobotsi ena e etsa hore HPMC e be le bokhoni bo betere ba taolo lits'ebetsong tse ling tsa taolo ea mocheso.
Phello ea sekhahla sa ho kuta ho viscosity
Tharollo ea metsi ea HPMC e bontša litšobotsi tse tloaelehileng tsa mokelikeli oa Newtonian ka litekanyetso tse tlaase tsa ho kuta, ke hore, viscosity e batla e tsitsitse; leha ho le joalo, ka litekanyetso tse phahameng tsa ho kuta, viscosity ea tharollo ea HPMC e tla fokotseha haholo, e bontšang hore e na le thepa ea ho kuta. Limolek'hule tsa HPMC li na le litšobotsi tse itseng tsa rheological. Ka litekanyetso tse tlaase tsa ho kuta, liketane tsa limolek'hule li sothehile haholoanyane, li etsa khanyetso e phahameng ea mohaho, e bonahalang e le viscosity e phahameng; ka litekanyetso tse phahameng tsa ho kuta, liketane tsa limolek'hule li atisa ho otlolla, ho phalla hoa matlafala, 'me viscosity e fokotseha.
Phello ea boleng ba pH ho viscosity
Tharollo ea metsi ea HPMC ka kakaretso e boloka viscosity e batlang e tsitsitse tlas'a maemo a fokolang a alkaline. Sebakeng se matla sa acid kapa tikoloho e matla ea motheo, limolek'hule tsa HPMC li ka 'na tsa e-ba le liphetoho tsa protonation kapa deprotonation, tse hlahisang liphetoho ho hydrophilicity, hydrophobicity le intermolecular interactions pakeng tsa limolek'hule, kahoo li ama viscosity ea tharollo ea metsi. Tlas'a maemo a tloaelehileng, liphetoho tsa pH ha li na phello e fokolang ho viscosity ea tharollo ea HPMC, empa tlas'a maemo a feteletseng a pH, phetoho ea viscosity e ka 'na ea bonahala haholoanyane.
Phello ea sebopeho sa limolek'hule ho viscosity
Litšobotsi tsa viscosity tsa HPMC li amana haufi-ufi le sebopeho sa eona sa limolek'hule. Tekanyo ea ho nkela sebaka sa hydroxypropyl le lihlopha tsa methyl molek'huleng e na le phello e kholo ho viscosity ea tharollo e nang le metsi. Ho phahama ha tekanyo ea ho kenya sebaka sa sehlopha, ho matlafala ha hydrophilicity ea HPMC le ho phahamisa viscosity ea tharollo. Ho feta moo, boima ba limolek'hule tsa HPMC hape ke ntlha ea bohlokoa e amang viscosity ea eona. Ha boima ba limolek'hule bo le khōloanyane, ketane ea molek'hule e telele, 'me ho matlafatsa likamano pakeng tsa limolek'hule, e leng se etsang hore ho be le viscosity e phahameng ea tharollo ea metsi.
3. Bohlokoa ba litšobotsi tsa viscosity tsa tharollo ea metsi a HPMC ha ho sebelisoa
Litšobotsi tsa viscosity tsa tharollo ea metsi ea HPMC li bohlokoa ts'ebelisong ea eona likarolong tse fapaneng.
Sebaka sa kaho: Hangata HPMC e sebelisoa ka seretse sa samente le likhomaretsi, 'me e na le mesebetsi ea ho tiisa, ho boloka mongobo, le ho ntlafatsa ts'ebetso ea kaho. Litšobotsi tsa eona tsa viscosity li ama ka ho toba ho sebetsa le ho khomarela seretse. Ka ho fetola sebopeho sa mahloriso le limolek'hule tsa HPMC, thepa ea rheological ea seretse e ka laoloa, kahoo e ntlafatsa boiketlo ba mohaho.
Indasteri ea meriana: Tharollo ea metsi ea AnxinCel®HPMC e atisa ho sebelisoa ha ho etsoa litokisetso tse kang lisebelisoa tse sa khaotseng tsa lithethefatsi, likhetla tsa capsule le marotholi a mahlo. Litšobotsi tsa eona tsa viscosity li ka ama sekhahla sa ho lokolloa ha lithethefatsi le ho laola mokhoa oa ho lokolloa ha lithethefatsi 'meleng. Ka ho khetha HPMC e nang le boima bo nepahetseng ba limolek'hule le tekanyo ea ho fetola, litšobotsi tsa tokollo ea lithethefatsi li ka fetoloa ho fihlela litlamorao tse nepahetseng tsa kalafo.
Indasteri ea lijo: HPMC e sebelisoa e le setenya, se tsitsitseng, le emulsifier ha ho etsoa lijo. Litšobotsi tsa viscosity tsa tharollo ea eona ea metsi li ama tatso le botsitso ba lijo. Ka ho lokisa mofuta le palo ea HPMC e sebelisitsoeng, sebopeho sa lijo se ka laoloa ka nepo.
Indasteri ea litlolo: HPMC, e le motenya le botsitso ho litlolo, e ka ntlafatsa sebopeho sa sehlahisoa, sa se fa metsi a loketseng le maikutlo a matle. Litšobotsi tsa eona tsa viscosity li na le tšusumetso ea bohlokoa boiphihlelong ba basebelisi ba lihlahisoa tse joalo ka litlolo, li-gel le li-shampoo.
Litšobotsi tsa viscosity tsaHPMC Litharollo tsa metsi li angoa ke lintlha tse ngata tse kang ho tsepamisa mohopolo, mocheso, sekhahla sa ho kuta, boleng ba pH le sebopeho sa limolek'hule. Ka ho lokisa lintlha tsena, ts'ebetso ea ts'ebeliso ea HPMC e ka ntlafatsoa ho fihlela litlhoko tsa liindasteri tse fapaneng bakeng sa thepa ea eona ea rheological. Patlisiso e tebileng mabapi le litšobotsi tsa viscosity ea tharollo ea metsi ea HPMC ha e thuse feela ho utloisisa thepa ea eona ea mantlha, empa hape e fana ka tataiso ea theory bakeng sa ts'ebeliso ea eona tlhahisong ea 'nete.
Nako ea poso: Jan-16-2025