HydroxypropypropyLese (HPMC)ke celukh Celllose cylukh cell kal molule e nkileng celukh celllow. Appearance is white to slightly yellow powder or granular material, tasteless, odorless, non-toxic, chemically stable, and dissolves in water to form a smooth, transparent and viscous solution. E 'ngoe ea thepa ea bohlokoahali ea hydroxypropyly methylceluse e sebetsang ke hore e eketsa pono ea mokelikeli. Phello ea thiletso e latela tekanyo ea sekhechana (DP) ea sehlahisoa, ho tsepamisa mohopolo oa Cellulose ka tharollo ea sejana se chesang le mocheso oa lithaelese. Le mabaka a mang.
01
Mofuta oa Mofuta oa HPMC se nang le bothata ba HPMC
Ka kakaretso, khatello ea metsi e phallang ka mela e ka hlahisoa e le mosebetsi oa tšobotsi ea shear ƒ eona feela e sa itšetleha ka nako. Ho latela mokhoa oa ƒ (ƒ (ƒ), maro a ka aroloa ka mefuta e fapaneng, e ka ba maro a Newtonia, maro a polasetiki a pjeudopprolit.
Ethe e 'nete e arotsoe ka mekhahlelo e' meli: e 'ngoe ke' na callulose ea ionico le leng le e 'ngoe ke iolilose ea ionic cellulose ether. Bakeng sa rheoloji oa mefuta ena e 'meli ea e-nile e le' ngoe ea cellulose. SC Naik et al. e ne e tšoarela thuto e felletseng le e tsamaisang khang ea hydroxethyl celdoulose le sodium celboxemethyl cellulolose tharollo. Liphello li bontšitse hore tharollo ea ether ea li-Ioni tsa Ioni ea Ioni ea Ioni e ne e le Litharollo tsa Eos e ne e le Pseudoplatmic. Ho phalla, ke hore ho phalla ha Newtonia, ho ea ho bacha ba bacha feela ka meaho e tlase haholo. Pseudoplapture of Hydroxypropyl Methylcelubulo tharollo tharollo ea bohlokoa e phetha karolo ea bohlokoa ho sebelisoa. Ka mohlala, ha e sebelisoa ka har'a likomelo tse tšesaane tsa tharollo ea metsi, vicoosity ea tharollo e fokotseha le karohano ea likolobe, hape e eketsa phalle ea koae . Phello e kholo haholo; Ha a ntse a phomotse, pono ea tharollo e kholo, e thibelang ho amoheloa ha linoko ka katleho e koahelang.
02
Mokhoa oa liteko oa HPMC
Letšoao la bohlokoa la ho lekanya phello ea khatello ea hydroxypropyLe methylcelulose ke pono e hlakileng ea tharollo ea metsi. Mekhoa ea litekanyo ea pono e hlakileng e kenyelletsa mokhoa oa lipampitšana oa lipolao, mokhoa oa ho potoloha oa liketsahalo le mokhoa oa ho oa.
Moo: Seboka se bonahala se bonahala, MPA s; K Na se elelloe se etsahalang kamehla; D ke letsoalo la sampole ea tharollo ho 20/1 ° C; Joa ke nako ea tharollo ea ho feta karolong e kaholimo ea lifoto ho isa ho Mareka e tlase, s; Nako ea hore oli e tloaelehileng e phalla ka senepe e lekantsoe.
Leha ho le joalo, mokhoa oa ho lekanya ka boemo ba hae bo botle ba caplillary o boima haholo. Linomo tsa ba bangataENDE ENSEHo thata ho sekaseka boemo ba ho sebelisa mokhoa oa capillary hobane tharollo ea bona e na le lintho tse sa tloaelehang tse bonoang ha motho ea emeng a e-na le pono. Ka hona, bahlahisi ba bangata ba sebelisa libapali tse potolohileng ho laola boleng ba hydroxypropyl methylcelulose. Litšiea tsa Brookfield li sebelisoa hangata linaheng tse ling, 'me Linomo tsa Linoko tsa NDJ li sebelisoa Chaena.
03
Lintlha tse ka ts'oereng pono ea HPMC
Kamano ea 3.1 le degree ea khale
Ha lipara tse ling li lula li sa fetohe, tse etsahalang tsa methylpropyl methylcelu ka tekanyo e lekanang le tekanyo ea li-polymerication (DP) Tšusumetso ena e bitsoa haholo boemong ba sekhahla se tlase ho feta boemong bo phahameng ba polymeriation.
3.2 likamano lipakeng tsa pono le khatello ea maikutlo
Lipakete tsa HydroxypropyL methylcelulose e eketseha ka keketseho ea khatello ea sehlahisoa se thata. Le phetoho e nyane ea mahloriso e tla baka phetoho e kholo ho Viscosity. Ka pono ea hydroxypropypropinyl methylceluse e ka sehloohong phello ea phetoho ea tharollo e hlakileng ea tharollo e totobetse haholoanyane.
3.3 Kamano pakeng tsa viscosity le sekhahla sa shear
Hydropxpropypropity Methylcelulose Antie e na le thepa ea shear. HydroxyproPypropinyL methylceluse ea pono e fapaneng ea pono e lokiselitsoeng tharollo ea bohlano ea 2%, 'me ke pono ea eona ka tsela e fapaneng ea li-shear e lekantsoeng ka mokhoa o fapaneng. Liphetho li ka etsahala joalo ka ha ho bontšitsoe ho setšoantšo. Ka lebelo le tlase, ke pono ea hydroxypropyl tharollo tharollo e sa fetoheng haholo. Ka keketseho ea sekhahla sa hele, liketsahalo tsa methapo ea hydroxypropyLulo ka ho hlaka le pono e kholo ha e fokotsehe hantle.
3.4 kamano pakeng tsa viscosity le mocheso
Kelello ea pono ea hydroxypropyl tharollo ea tharollo e anngoeng haholo ke mocheso. Ha mocheso oa eketseha, vicosion ea tharollo e fokotseha. Joalokaha ho bontšitsoe setšoantšong, e lokiselitsoe tharollo ea ho holofala ka khatello ea 2%, le phetoho ea semelo sa pono le keketseho ea Viscos e lekantsoeng.
3.5 Lintlha tse ling tse susumetsang
Litsie tsa tharollo ea hydroxypropyL methylcelulose le tsona li angoa ke litlatsetso ka tharollo, le pherekano ea likokomelo. Hangata, e le ho fumana ts'ebetso ea liketsahalo tse betere kapa fokotsa litšenyehelo tsa tšebeliso ea litlolo, e leng letsopa, phofo ea polyer, hodima phofo ea hydroxypropyproplay. le li-plomide tse kang chloride, brosidence, phosphate, nitssphate, jj. BIBELE ENA e ke ke ea ama thepa ea li-viscosicity feela e ke ke ea ama feela thepa ea lapeng, empa e boetse e ama thepa e ngoe ea kopo ea sesebelisoa sa hydroxyproplay joalo ka ho boloka metsi. , sag resing, jj.
Viscosion ea pherekano ea hydroxypropyl methylcelulose e batlang e sa anngoe ke acid le alkali, joalo ka sebopeho sa acid, acid acid, phosphoric acid, phosphoric acid , Boritic acid, citric acid, jj. Leha ho le joalo, acid e tsepamisitsoeng e ne e tla fokotsa li-viccoity. Empa testatic soda, potasiamo hydroxide, metsi a lime, joalo-joalo. Bapisoa le ethe ea selefounu,hydroxypropypropinyl methylcellTharollo ea maiketsetso e na le botsitso bo botle ba moea, lebaka le bohlokoa ke hore ho na le likelello tsa hydrogluloulose Ka ho nyonya khaello ea limolek'hule tsa ether le ketane ea ketane. Ts'ebetso ena ke hore pono e hlakileng ea tharollo e nyarosang e fokotseha. Haeba ho hlokahala ho boloka tharollo ea metsi a hydroxypropyLe methylcelluse ka nako e telele, ho khothalletsoa ho eketsa palo ea moetsi oa antifungal e le hore viscooity ha e fetohe haholo. Ha u khetha li-anti-fungl le lihlahisoa tse ling. e ka bapala karolo e lekanang.
Nako ea poso: Ap-28-2024