Sehlahisoa sena ke 2-hydroxypropyl ether methyl cellulose, e leng sehlahisoa sa semi-synthetic. E ka hlahisoa ka mekhoa e 'meli: (1) Ka mor'a ho phekola lithara tsa k'hothone kapa likhoele tsa makhasi a lehong ka soda ea caustic, li kopantsoe le chloromethane le epoxy Propane reacts, e hloekisitsoeng le ho siloa ho e fumana; (2) Sebelisa grade e loketseng ea methyl cellulose ho phekola ka sodium hydroxide, ho itšoara ka propylene oxide tlas'a mocheso o phahameng le khatello e phahameng ho ea boemong bo loketseng, le ho e hloekisa. Boima ba limolek'hule bo tloha ho 10,000 ho isa ho 1,500,000.
★ Khopolo e hloekileng ea tlhaho, e matlafatsa tšilo ea lijo le ho monya.
★ Metsi a tlaase, 5% -8%. Matla a ho monya mongobo, ha ho bonolo ho kopanya lintho tse ka hare, 'me khetla ea capsule ha e bonolo ho holofala, e fetoha brittle le ho thatafala.
★ Ha ho kotsi ea karabelo ea li-cross-link, ha ho tšebelisano, botsitso bo phahameng, kaha hydroxypropyl methylcellulose ke derivative ea cellulose, ha ho na kotsi ea ho kopana ha lintho tsa protheine ka gelatin.
★ Litlhoko tse tlase bakeng sa maemo a polokelo:
E batla e se brittle tikolohong ea mongobo o tlase, e na le botsitso bo botle mochesong o phahameng, 'me capsule ha e senyehe.
★ Maemo a tšoanang le tšebelisano e ntle:
E sebetsa ho litekanyetso tsa naha tsa pharmacopoeia, sebopeho, boholo, ponahalo le mokhoa oa ho tlatsa li lekana le li-capsules tse sekoti tsa gelatin, 'me ha ho hlokahale ho nkela lisebelisoa le likarolo sebaka.
★ Mohloli o seng oa liphoofolo, ha ho kotsi e ka bang teng ea ho hōla ha hormone kapa lithethefatsi tse setseng 'meleng oa phoofolo.
Hydroxypropyl methylcelluloseli-capsules tse se nang letho li fapane le li-capsules tse tloaelehileng tsa gelatin. Ke hydroxypropyl methylcellulose (HPMC) e entsoeng ka makhasi a lehong. Ntle le melemo ea mohopolo o hloekileng oa tlhaho, hydroxypropyl methylcellulose capsules e se nang letho hape E ka ntlafatsa ho monya le ho sila ha liprotheine, mafura le lik'habohaedreite, 'me e na le melemo ea tekheniki le litšoaneleho tseo li-capsules tse tloaelehileng tsa gelatin hollow li se nang tsona. Ka ntlafatso e tsoelang pele ea tlhokomeliso ea batho ea ho itlhokomela, nts'etsopele ea ho ja meroho, ho felisoa ha lefu la bohlanya ba likhomo, lefu la tlhako le molomo maphelong a batho, le tšusumetso ea bolumeli le lintlha tse ling, lihlahisoa tse hloekileng tsa tlhaho le tsa limela. e tla fetoha tataiso e ka sehloohong bakeng sa nts'etsopele ea indasteri ea capsule. .
Nako ea poso: Apr-28-2024