Hydroxypropypropinyl Methylcellll (HPMC) ke tšebeliso e fapaneng ea indasteri e fapaneng ka lebaka la thepa ea eona e ikhethang. Sengoliloeng sena se fetela ka thata ka ho hlaka ha HPMC, e hlahloba sebopeho sa sona sa lik'hemik'hale, thepa, mesebetsi le lits'ebeletso tse fapaneng. Ho tloha ho pharmatucations ho ea kalong, lihlahisoa tsa lijo ho lintho tsa tlhokomelo ea botho, HPMC e bapala karolo ea bohlokoa, e bonts'a bohlokoa ba eona molemong oa tlhahiso ea sejoale-joale.
HydroxypropypropinyL methylcellll (HPMC) ke tšebeliso e kholo ea celbulose e fetotsoeng ho phaltingcy ho tloha ho pharing ho tloha ho pharing Thepa ea eona e ikhethang e etsa hore e be molaong lits'ebetsong tse fapaneng, e kenya letsoho botsitso, pono le ts'ebetso ea lihlahisoa tse ngata.
1.Chemical sebopeho le thepa
HPMC e kenella ka tsela ea alkali Chloulose ea Alkali le Presyi Oxide ea Hydroyl ka kemiso ea Hydrous. Phetoho ena e fana ka thepa e ikhethang ho HPMC, ho kenyelletsa le alloubility ea metsi, ho itšehla thajana, matla a ho etsa lifilimi le taolo e ntle ea lifilimi, taolo e ntle ea lifilimi le taolo e ntle ea lifilimi.
Tekanyo ea sebaka (DS) le boima ba limolek'hule li susumetsa marulelo a HPMC. DS e phahameng e ntlafatsa slleudity ea metsi mme e fokotsa mocheso oa borena, ha boima ba lisele bo fana ka maikutlo a liketsahalo le litšobotsi tse etsang lifilimi. Mesebetsi ena e kopaneng e etsa hore HPMC e ikamahanya le maemo a fapaneng lits'ebetsong tse fapaneng.
2. Pele ho HPMC
Taolo ea ho holisa le Rheology: HPMC e sebetsa e le moemeli oa thipa litharong tse ntle, tse hlahisang liketsahalo le ho ntlafatsa botsitso ba liforomo. Boitšoaro ba eona ba pseudoplat ka mokhoa o lumellang taolo ea lintho tsa bootsoa, e tsamaisang tlhahiso ea lihlahisoa ka thepa e lakatsehang ea phallo e lakatsehang.
Setlhare sa lifilimi: Ka lebaka la bokhoni ba eona ba ho etsa lifilimi tse pepenoang, HPMC bo sebelisitsoe haholo ka har'a likomelo, matlapa a meriana le lihlahisoa tsa tlhokomelo ea botho. Lifilimi tsena li fana ka lisebelisoa tsa katse, ho boloka mongobo le ho lokolloa ha metsoako e mafolofolo.
Litokiso tsa metsi: lisebelisoa tsa kaho e joalo ka likelello, likepe, le marias, HPMC li ntlafatsa ho foqoha ha metsi nakong ea ho folisa. Sena se ntlafatsa moea, o fokotsa ho bola, 'me o netefatsa hydration e tšoanang ea metsoako e mameljha.
Tlama le ho senyeha ha meriana, ho etsa HPMCC ho sebetsa e le 'mila, o tšoere metsoako e sebetsang ea Mabothong, li-capsules le li-granules. Ho feta moo, bokhoni ba eona ba ho tšolla le lithuso tse mashome a mararo ho mecha ea mecha ea phatlalatso ea lithethefatsi tse laoloang ke lithethefatsi.
Stabilizer le Emulfier: HPMC e tiisa lipela, litsi le litlolo tsa lijo, le litloholo tsa litlolo le litloholeiti. E thibela karohano ea kholo, e boloka mokhoa, e boloka liphallelo, le ho phela bophelo ba Shelf ka ho thibela kholo ea likokoana-hloko le oxidation.
3.Lona ea HPMC
PharmacEical: HPMC ke motsoako oa bohlokoa ho mefuta ea litekanyetso tsa molomo e tiileng e kang litafole, li-capsules le li-pellets. Karolo ea eona e le moqapi, ho senyeha, ho senyeha ha mosebetsi o laoloang ho tiisa hore ho na le katleho.
Kaho: indasteri ea kaho, HPMC e eketsoa lisebelisoa tse thehiloeng ho tumello ea ho ntlafatsa ka mmele ho ntlafatsa menyetla, boloka metsi le thepa ea likhoto. E ntlafatsa ts'ebetso ea likelello, likepe, ho thula, ho etsa mekhabiso e tšoarellang le e khahlisang haholo.
Lijo le lino tse tahang: tsa hpmc li fumana kopo ho tsejong tsa lijo e le bolo ea maoto, le emumolizer. E sebelisoa hangata ka mafu, liaparo, mefuta e meng ea lebese le lintho tse ling tsa ho ntlafatsa mokhoa, molomo le bouliti
Tlhokomelo ea Botho: Li-cosmetics le Lihlahisoa tsa Botho, HPMC e sebetsa joalo ka filimi ea pele, thickener le ho emisoa. E teng ka lisele, loutions, shampoos le meno, ho fana ka maikutlo a ho lakatseha le ho ntlafatsa ts'ebetso ea sehlahisoa le ho ntlafatsa tšebetso ea sehlahisoa.
Li-peta le lipuisano: HPMC e sebelisoa lipelong tse thehiloeng metsi, mabaka le maiketsetso a ho ntlafatsa pono, le ho ntlafatsa sebopeho sa baesekopo. E khothalletsa kopo ea junifomo, ho tšoarela ho subrate, le ho tšoarella ha metsi a mangata.
Litlhohonolofatso le liphephetso tsa
Leha o sebelisa le ho feto-fetoha ha ona ho pharalletseng le ho qhekella, mathata a kang ho feto-fetoha ha litch-to-to-archis ho phehella tlhahiso le tšebeliso ea hpmc. Boiteko ba ho etsa lipatlisiso bo lumela ho sebetsana le mathata ana le litsela tse khothatsang tsa Synthes tsa li-syrevatis tsa HPMC.
Hydroxypropypropinyl Methylcelllll (HPMC) ke karolo ea malinyane a fapaneng ka likopo tse fapaneng ka ho pholletsa le phapanyetsano, ea kaho, lijo le likarolong tsa botho le likarete tsa motho. Motsoako oa eona o ikhethang oa thepa, ho kenyelletsa ho boloka metsing, ho boloka metsing, ho boloka metsi le bokhoni ba ho tsitsisa hoa lihlahisoa tsa sejoale-joale le ntlafatso ea sehlahisoa. Ka ho utloisisa sebopeho sa lik'hemik'hale, thepa le mesebetsi ea marang-rang, indasteri e ka baka mekhoa e phahameng ea basebelisi le mebarakeng.
Poso: Feb-29-2024