Hypromellose ke eng?

Hypromellose (hydroxypropyLe methylcelll, HPMC): tlhahlobo e felletseng

1. Selelekela

HypromelloseHape, hape e tsejoang e le hydroxypropyl methylcelllll (HPMC), ke Polyynthetic Polymer e tsoang cellulose. E sebelisoa haholo ho li-pharmacleical, Lihlahisoa tsa lijo, litlolo tsa lijo le litsi tsa kaho. Ka lebaka la tlhaho eo e seng ea chefo, e etsang phetisetso ea filimi, hypromellose e fetohile motsoako oa bohlokoa ho likhau tse fapaneng.

Tokomane ena e fana ka tlhahlobo ea kelello ea hypromellose, ho kenyelletsa le thepa ea eona ea lik'hemik'hale, likomiti, boithuti ba polokeho le taolo ea polokeho.

2. Sebopeho sa lik'hemik'hale le thepa

Hypromelllose ke nomoro ea celdroulo e fetotsoeng lik'hilomithara ka lik'hilograma. Boima ba limolek'hule bo fapana ho latela degree ea sebaka le polymerication.

• Fulle:O qhibiliha metsing, a theha tharollo ea viscous; Ho itšenya ka Ethanol le li-solvents tse ling.
• Viscosity:E fumaneha ka libaka tse fapaneng tsa li-viscoities, e etsang hore e na le thuso bakeng sa lits'ebeliso tse fapaneng.
• PH botsitso:E tsitsitseng ka ho pholletsa le blood e sephara (3-11).
• Leemela la Formal:E etsa setlhare sa ho futhumatsa, sethala sa senotlolo sa liforomo tse laoloang - lokollotsoeng.
• Tlhaho e seng ionic:E tsamaisana le metsoako e fapaneng ea meriana e sa sebetseng ea meriana (APIS) ntle le ts'ebelisano ea lik'hemik'hale.

3. Synthesis ea hypromellose

Ho hlahisoa ha hypromese ho kenyelletsa mehato e latelang:

1. Pensilose ea Cellulose:E tsoa likhoele tsa limela, haholo-holo pulp kapa k'hothone.
2. Alkalization:Tšoaroa ka sodium hydroxide (naoh) ho ntlafatsa boikhethelo.
3. Phapanyetsano:E arabiloe ka methyl chloride le procelone oxide ho hlahisa lihlopha tsa mekhoa le hydropyl.
4. Tlhoekiso le ho omisa:Sehlahisoa sa ho qetela se hlatsoitsoe, se omileng le se nang le sona se halikiloeng ka tšohanyetso le sebopeho sa pono.

4. Likopo tsa Hypromellose

4.1 indasteri ea pharmaceutical

Hypromelllose e sebelisoa haholo ka har'a litlhare tsa meriana ka lebaka la sebopeho sa eona se etsang lifilimi, e bilika e bileng

• Coating Coating:E etsa sekala se sirelletsang ho potoloha leable ho ntlafatsa matla a tsitsitseng le a mokuli.
• Ho lokolloa ho matlafatsang le ho laolehang:E sebelisoang tatlengtsong ea matrix le gel ea li-hydrophilic ho laola ho khesoa ha lithethefatsi.
• Capsule Liat:E sebeletsa e le mofuta oa meroho ho li-capsules tsa gelatin.
• E hlomphehang ka marotholi a mahlo:E fana ka pono le ho boloka nako e tenyetsang ho thunya ho otla litharollo tsa litharollo tsa ophthal.

4.2 Likopo tsa Lithohllhamic

Hypromelllose ke motsoako oa bohlokoa meokho ea maiketsetso le marotholi a mahlo a mahlo:

• Phekolo ea drerome e omileng ea mahlo.E sebetsa e le mongobo oa mongobo ho imolla ho omella ka mahlo le ho teneha.
• Ikopanye le litharo tsa Lens:E ntlafatsa matšeliso a matšeliso ke ho fokotsa likhohlano le ho ntlafatsa hydration.

4.3 indasteri ea lijo

E le hore lijo tse lumelletsoeng tsa lijo tse lumelletsoeng (e464), hypromellose e sebeletsa merero e fapaneng mosebetsing oa lijo:

• Moemeli oa Thickening:E ntlafatsa sebopeho le botsitso ho li-soces, liaparo le lihlahisoa tsa lebese.
• Emulifier le Stabilizer:E boloka e tsitsipanya lijo tse siiloeng le lino.
• Vegan gelatin deft:E sebelisoang lihlahisoa tse thehiloeng ho limela le lintho tsa confectionery.

Li-cosmetics tsa 4.4 le tlhokomelo ea botho

Hypromellose e sebelisoa haholo ka botle le lihlahisoa tsa letlalo:

• Liroboto le litlolo:E sebetsa e le bolo ea thipa ebile e le thata.
• Shampoos le Batho ba Ikemetseng:E ntlafatsa pono ea pono le ts'ebetso ea ho etsa lintho.
• Lihlahisoa tsa litlolo:E ntlafatsa puo ea mascaras le metheong.

4.5 Likopo tsa Kaho le tsa Indasteri

Ka lebaka la ho boloka metsi le bokhoni ba ho etsa lifilimi, hypromellose e sebelisoa ho:

• Samente le ho bokelloa:E ntlafatsa ho ba le boikarabello le ho fokotsa tahlehelo ea metsi.
• Paints le Likotsi:E sebetsa joalo ka binder le ba hlolloang.
• Li-sexter:E ntlafatsa inccosity in baiti ba metsi.

5. Kaho ea polokeho le taolo e nchafatsang

Hypromellose hangata e amoheloa ka mokhoa o sireletsehileng (cras) ka lijo tsa morao-rao, ho kenyeletsoa le tsamaiso ea lithethefatsi le tsamaiso ea lithethefatsi (FDA) le bolaoli ba polokeho ea Europe (Efsa). E na le chefo e nyane ebile e se khopisang ha e sebelisoa ka har'a meeli e khothalelitsoeng.

6. Litlhare tse ka bang litlamorao

Ha hypromelllose e bolokehile bakeng sa basebelisi ba bangata, litla-morao tse ka bang moo e ka bang li kenyelletsa:

• Ho teneha mahlo a bonolo:Maemong a sa tloaelehang ha o sebelisoa marotholi a mahlo.
• Ho hloka kutloano:Ts'ebeliso e mpe ea lihlahisoa tsa lijo e ka baka ho thunya.
• Boitšoaro ba Allergic:Se sa tloaelehang haholo empa ho ka etsahala ka batho ba tebileng.

Hypromelloseke motsoako oa bohlokoa indastering e ngata e ngata, e ile ea ananelela linthong tsa eona tse nang le chefo, tse fapaneng le tse sa tsitsiseng. Karolo ea eona ho meriana, lijo, litlolo, tsa litlolo tsa indasteri le likou li ntse li eketseha, ho li etsa ea likholomo tse sebelisetsoang cellulose ka ho fetisisa lefatšeng ka bophara.