Hydroxypropitypropiyprokhullose (HPMC) le carboxyMethylCalEulose (CMC) ke mefuta e 'meli e fapaneng ea polymis e sebelisoang ho kokobetsa matšoao a mahlo. Although they share some similarities, these two compounds have clear differences in their chemical structure, properties, mechanism of action, and clinical applications.
Hydroxypropypropypropiny methylcelllulo (HPMC) marotholi a mahlo:
1.Chemical sebopeho:
HPMC ke moitlami oa maiketsetso oa cellulose, polymer ea tlhaho e fumanehang marakong a cel.
Lihlopheng tsa hydroxypropyl le lihlopha tsa methyl li kenngoa motheong oa cellulose, li fana ka thepa e ikhethang ea HPMC.
2. Viscosity le Rheology:
HPMC Marotholi a leihlo a HPMC ka kakaretso a na le pono e phahameng ho feta marotholi a mang a tlotsitsoeng.
Maeto a eketsehileng a eketsehileng a thusa marotholi a setseng ka har'a naha, e fana ka maikutlo a nako e telele.
3. Mechanism ea ketso:
HPMC e theha sekala se sirelletsang le se khahlisang ka holim'a bokaholimo, se fokotsa likhohlano le ho ntlafatsa botsitso ba lifilimi.
E thusa ho kokobetsa matšoao a leihlo le ommeng ka ho thibela moferefere o fetelletseng oa meokho.
4. Kopo ea Clinical:
Marotholi a mahlo a HPMC a tloaetse ho tšoara lefu la mahlo.
Li boetse li sebelisoa ka liofisiri tsa mahlo le lingaka ho boloka khatello ea litoropo.
5. Melemo:
Ka lebaka la pono e phahameng, e ka eketsa nako ea bolulo e sebakeng se nang le maikutlo.
Ka katleho ho fokotsa matšoao a leihlo le ommeng mme a tšelisa.
6. Litsietsi:
Batho ba bang ba ka ba le pono e senyehileng hang ka mor'a hore ke pono e eketsehileng.
CarboxyMethylCalEulose (CMC)
1.Chemical sebopeho:
CMC ke sesebelisoa se seng se ntlafalitsoeng se fetotsoeng le lihlopha tsa carboxyMethl.
Kenyelletso ea sehlopha sa carboxyMer sehlopha se ntlafatsa qubu ea metsi, e etsang CMC e qhomelang metsi.
2. Viscosity le Rheology:
Marotholi a leihlo a cmc ka kakaretso a na le pono e tlase ha e bapisoa le marotholi a mahlo a HPMC.
Viscosity e tlase e lumella thepa e bonolo le ho hasoa kapele ka potlako ka holim'a metsi.
3. Mechanism ea ketso:
CMC e sebetsa e le lubricant le Humectant, e ntlafatsa botsitso ba lifilimi.
E thusa ho kokobetsa matšoao a leihlo a ommeng ka ho khothaletsa ho lema mongobo sebakeng sa leihlo.
4. Kopo ea Clinical:
Marotholi a mahlo a cmc a sebelisetsoa ho imolla matšoao a leihlo le ommeng.
Ka kakaretso li khothalelitsoe batho ba nang le lefu la mahlo le itekanetseng.
5. Melemo:
Ka lebaka la papiso ea eona e tlase, e namela kapele mme ho bonolo ho e rotha.
Ka katleho le ka potlako ho imolla matšoao a leihlo kapele.
6. Litsietsi:
Ho etsa lintho khafetsa ho ka hlokahala ho feta ha ho bapisoa le liforomo tse phahameng tsa pono.
Litokisetso tse ling li kanna tsa ba le nako e khuts'oane ea ketso ka har'a naha.
Tlhahlobo e patehileng:
1. Vecosity:
HPMC e na le pono e phahameng, e fana ka phomolo e telele e telele le tšireletso e matla.
CMC e na le pono e tlase, e lumellang ho jala kapele ebile e le bonolo.
2. Nako ea Ketso:
HPMC ka kakaretso e fana ka nako e telele e telele ka lebaka la pono ea eona e phahameng.
CMC e kanna ea hloka dollal ea khafetsa, haholo maemong a leihlo le omileng.
3. Matšeliso a Mamela:
Batho ba bang ba ka fumana hore marotholi a mahlo a hpmc a baka phetho ea nakoana ea pono ka lebaka la pono ea bona e phahameng.
Marotholi a mahlo a cmc ka kakaretso a mamelletsoe hantle 'me a etsa hore ho be le litšila tsa pele.
4. Litlhahiso tsa bongaka:
HPMC hangata e khothalletsoa batho ka mokhoa o itekanetseng oa ho opa habobebe.
CMC hangata e sebelisoa ho tse bonolo ho mahlo a silafetseng le bakeng sa ba ratang foromo e tlase ea viscous.
Hydroxypropitypropiyprokhullose (HPMC) le carboxyMethylCalEulose (CMC) Litsuhelo tsa mahlo ka bobeli ke likhetho tsa bohlokoa tsa ho phekola matšoao a mahlo. Khetho pakeng tsa tse peli e itšetlehile ka khetho ea motho, ho teba ha leihlo le ommeng, le nako eo u e batlang. Lipapali tse phahameng tsa HPMC li fana ka ts'ireletso e telele e tšoarellang, ha Viscossity e tlase e fana ka liphallelo kapele mme e kanna ea ba khetho ea pele ho batho ba tsotellang pono e Fosahetseng. Litsebi tsa li-ophthalmologgs le litsebi tsa mahlo a mahlo ha li ntse li khetha marotholi a mahlo bakeng sa bakuli ba bona, li reretsoeng ho ntlafatsa matšeliso le ho imolla matšoao a leihlo le ommeng.
Nako ea poso: Dec-25-2023