Ukusetyenziswa kwe-HPMC kumzi-mveliso wamachiza

I-Hydroxypropyl Methylcelceltulose (HPMC), ekwabizwa ngokuba yi-hypromellose, isetyenziswa ngokubanzi kumzi-mveliso wamayeza ngenxa yezinto zayo eziguquguqukayo. Nazi ezinye iinkqubo eziqhelekileyo ze-HPMC kwi-Hermaceuticals:

1. Ithebhulethi yetafile: I-HPMC isetyenziswa njenge-binder kwifomu yecwecwe kwithebhulethi ukudlulisela ulwalamano kunye nokuphucula ubunzima betafile. Kuyanceda ukubamba izithako ezinamafutha kunye ngexesha lokucinezelwa, kukhokelela kwiitafile kunye nokufana noomatshini.
2. I-filder yefilimu yokuhlalisa ifilimu: I-HPMC isetyenziswa njengearhente yokudibana kwefilimu ukuba ibonelele ngokukhusela kunye / okanye ubuhle kwitafile nakwiicaphule. Ukudibana kwefilimu kuphucula inkangeleko, imaski yemaski, kunye nokuzinza kwefom yethamo lemifanekiso. Ukongeza, inokulawula i-kinetics yokukhupha i-kinetics, khusela ichiza kumswakama, kunye nokwenza lula ukuginyaniswa.
3. IMatrix yangaphambili: I-HPMC isetyenziswa njenge-matrix yangaphambili yokukhutshelwa-kulawulwa kunye nokukhutshwa kwebhubhu yecwecwe. Yenza i-gel fer kwi-hydration, elawula ukwahluka kwechiza kwi-dosage form, ekhokelela ekukhululweni kweziyobisi ixesha elide kunye nesiphumo sonyango.
4. Intsholongwane: Kwezinye iindlela, i-HPMC inokuthatha amanyathelo njenge-chinterbrant, ikhuthaza ukwahlukana ngokukhawuleza kunye nokusasazwa kweetafile okanye iicapbule kwi-gestrointenal phecanal. Oku kuququzelela ukuchithwa kweziyobisi kunye nokuthathwa, ukuqinisekiswa kwebhayili efanelekileyo.
5. I-Viscosity Modifier: I-HPMC isetyenziswa njengendawo yokuguqula i-viscosity kwifomuli ye-Liquid kunye nefomu eqinileyo njengokumiswa, ii-emuls, iiglasi, kunye namafutha. Inika ulawulo lwe-rucialogical, liphucula uzinzo lokunqunyanyiswa, kwaye luphucula ukusasazeka kunye nokunamathela kwimilinganiselo yokuphatha.
6. I-Stabliber kunye ne-eUlsifier: I-HPMC isetyenziswa njengesiqhelo kunye ne-emulsifier kwifomu yokuthintela ukwahlulwa kwenqanaba, ukuphucula uzinzo, kunye nokonyusa i-homogeneity yemveliso. Iqhelekile isetyenziselwa ukumiswa komlomo, isiraphu kunye nokuFulsions.
7. Iarhente yokuthambisa: I-HPMC isetyenziswa njengearhente yokuthambisa ngexesha lokumiselwa kwezinto ezahlukeneyo zokwandisa i-viscofity kunye nokubonelela ngeepropathi zeRhaiology. Iphucula ukuthungwa kunye nokuhambelana kwamalungiselelo aphezulu njengekhrim, i-lotions, kunye ne-Gels, ukuphucula ukusasazeka kwabo kunye nolusu.
8. I-Opacifier: i-HPMC inokusetyenziswa njengearhente eqingqiweyo kwifomu ethile yokudlulisela i-opacity okanye i-opareyty yolawulo. Le ndawo iluncedo ikakhulu kwifomu ye-Ophthalmic, apho i-Opacity inokuphucula ukubonakala kwemveliso ngexesha lolawulo.
9. Isithuthi seenkqubo zokuhanjiswa kweziyobisi: I-HPMC isetyenziswa njengemoto okanye inqwelo-mafutha kwiinkqubo zokuhambisa iziyobisi ezinje ngee-microsshes, i-nanopalicals, kunye nee-hydrogels. Ingakwazi ukuchaza iziyobisi, ulawulo lweziyobisi ukukhulula i-kinetics, kunye nokomeleza uzinzo lwamayeza, ukubonelela ngokuhanjiswa kweziyobisi kunye nokulawulwa kweziyobisi.

I-HPMC yindlela yokuthabatha i-pharaceouting enoluhlu olubanzi lwezicelo, kubandakanya ukubopha itafile, ukudityaniswa kwefilimu, ukulungiswa kwe-matrix, ukulungiswa kwe-matrix, ukulungiswa, ukwenziwa kwenkqubo yokuhambisa iziyobisi. Ukusetyenziswa kwayo kunegalelo kuphuhliso lwemveliso ekhuselekileyo, esebenzayo, nenobuhlobo.