Hydroxypropyl methylcelculose (hpmc) Ngaba i-polymer yendalo isetyenziswe ngokubanzi ekwakhiweni, amayeza, ukutya kunye namanye amasimi. Kwishishini lesamente, i-Nqulcel®HPMC ihlala isetyenziswa njengesongezo ekuphuculeni intshukumo yesamente, kwaye iphucule inkqubo yokudityaniswa, i-ofisi yokugqibela yesamente.
1. Iimpawu ezisisiseko kunye nendlela yesenzo se-HPMC
I-HPMC yinkathalo yemichiza efunyenwe ngokuguqula i-Selase nge-hellyting, i-hydroxyyplopy kunye ne methym. Ulwakhiwo lwayo lwemolekyuli lubandakanya amaqela amaninzi e-hydrophobic kunye ne-hydrophobic, eyenza ukuba idlale iindima ezininzi kwiinkqubo zesamente. I-HPMC idlala le micala ilandelayo yesamente:
Isiphumo sokutyibilika
I-HPMC inefuthe eliqatha eliqatha kwaye inokuphucula kakhulu i-viscofity yesamente inamathisele iyunifomu engaphezulu ngexesha lokuxuba kunye nokuphepha i-spotting okanye i-sedation. Oku kubaluleke kakhulu ekuphuculeni ulwelo kunye nokuzinza kwesamente inamathisele kwikhonkrithi ephezulu okanye ezinye izinto ezifunwayo zesamente, ukuqinisekisa ukuba igcwalisa imbangi engcono kwaye inesifo esiphezulu.
Ukuphucula ukugcinwa kwamanzi
I-HPMC ikwazi ukulawula ngokufanelekileyo inqanaba lokuphuma kwamanzi kwi-CEATE DEATE kwaye ulibazise indawo yokuqala yexesha lesamente. Ingakumbi kubushushu obuphezulu okanye indawo eyomileyo, inokugcina ukukhululwa kwesamente inamathisela kwaye kuthintele ukomisa ngaphambi kwexesha, ngaloo nto iphucule ukusebenza kwezokwakha. Ukugcinwa kwamanzi yipropathi ebaluleke kakhulu kwinkqubo yokwakha izixhobo zesamente kwaye unokuthintela ngokufanelekileyo ukumiswa kwemifuno.
Ukuphucula ububi kunye nokuphucula i-fluids
Ezinye izinto ezongezelelekileyo zekhemikhali zihlala zongezwe kwi-qualth parte, ezinjengeepolimers, ukungqinwa kweminerali, njl njl. I-HPMC inokunyusa amandla e-ceng yesamente, esenza iplastiki engaphezulu kunye nolwelo, ngaloo ndlela iphuculayo ukusebenza kokwakha. Ukongeza, i-HPMC inokuphucula i-adhesion phakathi kwesamente kunye nezinye izinto zokwakha (njengesanti kunye negrabile) kwaye zinciphise ukwahlulahlula.
Ukuphucula ukunganyangeki kwe-rack
Ukususela oko i-Nuntyl®HPMC inokuphucula ukugcinwa kwamanzi kwisamente kunye nokulibazisa inkqubo ye-hydrate, inokuphucula ngokufanelekileyo ukunganyangeki kwesamente. Ingakumbi elona nqanaba lokuqala xa amandla edini engafikeleli kwinqanaba elaneleyo, izinto zesamente zithambekele ku-rocks. Ngokusebenzisa i-HPMC, inqanaba le-shrinkage yesamente linokucothiswa kwaye ukwakhiwa komzimba okubangelwa kukulahleka kwamanzi ngokukhawuleza kunokuncitshiswa.
2. Isiphumo se-HPMC kwisicelo sesamente
Ukuphucula ukusebenza kwesamente
Iziphumo zokonga le-HPMC zenza ukuba isamente ichithe ngakumbi. Ngeentlobo ezahlukeneyo zesamente (efana nesamente eqhelekileyo, isamente ekhawulezileyo, njl. Njl.), I-HPMC inokwandisa ulwalamano lwe-slidity kwaye luququzelele ngexesha lokuqalisa. Ukongeza, i-HPMC inokwenza isamente icothise ngakumbi ngexesha lokwakha, ukunciphisa igalelo lomoya, kunye nokuphucula umgangatho wokwakha.
Ukuphucula amandla e-qumence
Ukongezwa kwe-HPMC kunokuphucula amandla okusebenza kwesamente ukuya kuthi ga kwinqanaba elithile. Itshintsha ukwabiwa kwamanzi kwisamente, ikhuthaza i-hydration ye-hydrations elinganayo yamasuntswana, kwaye oko ke kuphumelisa amandla okuqina okokugqibela. Kwizicelo ezisebenzayo, ukongeza isixa esifanelekileyo se-HPMC sinokukhuthaza ukuphendula kwe-hydration yesamente kunye nokuphucula ubuchule, abaguquguqukayo nabanesifo sesamente.
Ukuqina okuphuculweyo
Ukongezwa kwe-HPMC kuyanceda ukuphucula ukuqina kwesamente. Ngokukodwa xa ingubo ivezwa kwiindawo ezinobuchule (ezinje nge-acid, ialkali, i-saline, njl.), I-HPMC.), I-HPMC, njl. Ukongeza, i-HPMC inokunciphisa ukutyeba kwe-capillary yesamente kunye nokonyusa ukuxinana kwesamente, ngaloo ndlela kuncitshiswa iqondo layo elinzima kwiindawo ezinobunzima.
Ukuphuculwa kweenguqulelo zokusingqongileyo
Phantsi kweemeko zemozulu ezigqithileyo, ukwenziwa kwesamente kuhlala kuhlala kuchaphazeleka lutshintsho kumaqondo obushushu kunye nokufuma. I-HPMC inokulibazisa ukusetwa kwexesha lokutyibilika kunye nokunciphisa iingxaki ezibangelwa kukomile ngokukhawuleza okanye ngokugqithisileyo. Ke ngoko, ifaneleke ngakumbi imeko yokwakha iqondo lobushushu obuphezulu, ubushushu obuphantsi kunye notshintsho olukhulu lokufuma.
3. Ukusetyenziswa ngokugqibeleleyo kwe-HPMC
Nangona ukusetyenziswa kwe-HPMC e-HPMC e-HEATMC kunokuphucula kakhulu ukusebenza kwayo, ukusebenzisa kwayo kufuneka kulumkele, ngakumbi kwisixa esongeziweyo. Ukongeza okugqithisileyo kwe-HPMC kunokubangela ukuba i-viscosity yesamente inamathisele kakhulu, kubangele ukuba kudityaniswe okanye ubunzima bokwakha. Ngokubanzi, isixa se-HPMC esongeziweyo kufuneka silawulwe phakathi kwe-0.1% kwaye i-0,5% yesamente, kwaye ixabiso elithile kunye nendawo ethile yendawo yokuhlala.
Imithombo eyahlukeneyo, imigaqo kunye nezidanga zokuguqulaI-HPMC Inganeziphumo ezahlukeneyo kwizibonelelo zesamente. Ke ngoko, xa ukhetha i-HPMC, imiba enjengobunzima bemolekyuli, i-hydroxypropy kunye ne-methytration ithathelwe ingqalelo ngokufanelekileyo ukufumana olona luguquko lufanelekileyo. Isiphumo.
Njengesimo sesamente ebalulekileyo, iAincencel®HPMC iphucula kakhulu ukusebenza, amandla, ukuqina kwendalo yokusebenza, ukuphucula ukugcinwa kwamanzi, ukuphucula ukunamathela kunye nokunganyangeki. Isicelo sayo ngokubanzi kwishishini lesamente asingaphumi nje ukusebenza kwesamente, kodwa ikwabonelela ngenkxaso eqinileyo yophando kunye nophuhliso lweemveliso ezintsha zesamente ezifana nekhonkrithi yokusebenza enobuhlobo kunye nendalo yokwakha. Njengoko iiprojekthi zokwakha ziyaqhubeka nokwandisa iimfuno zabo zokusebenza kwezinto, i-HPMC zinamathuba okusebenzisa izicelo ezikwishishini lesamente kwaye ziya kuqhubeka ziyinto ebalulekileyo yokulungiswa.
IXESHA LOKUQALA: UJan-16 ukuya ku-15