Iimpawu zeTekhnoloji yobushushu ephezulu yeHydroxypropyl Methylcelcelceluplose

Hydroxypropyl methylcelculose (hpmc)Yinto ebalulekileyo yeekhemikhali, isetyenziswa ngokubanzi kwizinto zokwakha, amayeza, ukutya kunye namanye amasimi. Ingakumbi kumzi-mveliso wokwakha, i-HPMC isetyenziswa ngokubanzi ngenxa yokusebenza kwayo ngokugqibeleleyo. Itekhnoloji yobushushu ephezulu idlala indima ebalulekileyo kwimveliso kunye nokusetyenziswa kwe-HPMC.

1. Indima yeTekhnoloji yobushushu ephezulu kwi-HPMC

Imveliso yeDethylcelcelceltulose ifunyenwe ngongcelele lwemichiza yekhemikhali efana nokuphumelela kunye nokuthengiswa kwe-ether yendalo. Itekhnoloji yobushushu ephezulu isetyenziswa ikakhulu ekuphelisweni, ukomisa kunye nokubumba kwenkqubo yokuphendula. Unyango lobushushu oluphezulu alunakukhawulezisa kuphela izinga lokuphendula, kodwa kukuphucula ubunyulu kunye nokuzinza kwemveliso.

Ukuphuculwa kokuphendula ngokuphuculweyo

Phantsi kweemeko zobushushu obuphezulu, izinga lokuphendula kwe-sellulose kunye ne-sodium hydroxide ikhawuleziswa, ekhuthaza i-HydroxyPropy ye-Hydropyl kunye ne-HydroxyPropy ye-Hydropyl kunye ne-HydroxyPropy ye-Hydropyl kunye neMethyl

Susa izinto ezingcolileyo

Imeko yobushushu ephezulu inokususa ngokufanelekileyo iimveliso eziveliswa ngexesha lokuphendula, njengesisombululo se-alkali engadibaniyo kunye nesinyibilikisi, kunye nokuphucula ubunyulu be-HPMC.

Ukuphuculwa kokusebenza kakuhle

Ngexesha lenkqubo yokomisa amaqondo obushushu, umswakama we-HPMC wakhupha ngokukhawuleza, ukunqanda imveliso ekubeni i-ageglomeradration okanye itshintshe amaqondo obushushu asezantsi, kunye nokuphucula ukusebenza kwemveliso.

2. Ifuthe leTekhnoloji yobushushu ephezulu kwi-HPMC

Itekhnoloji yobushushu ephezulu ayichaphazeli ukwakhiwa komzimba kwe-HPMC, kodwa ikwanempembelelo enkulu kwiipropathi zekhemikhali kunye neziphumo zokwenza isicelo.

Ulungelelwaniso lwe-viscosity

Inkqubo yobushushu obuphakamileyo inokulawula ngokufanelekileyo ukuhanjiswa kwesisindo kwe-HPMC, ngaloo ndlela kulungelelanisa uVelweni lwayo. Amaqondo obushushu aphezulu anceda ukunciphisa amathuba okuqhankqalaza kwe-molecular, esenza i-HPMC kwisisombululo esiqingqiweyo.

Ukumelana nobushushu obuphuculweyo

Uzinzo lwe-shirm le-HPMC luphuculwe kakhulu unyango oluphezulu lobushushu. Ekwakheni udaka kunye ne-Tilheves, i-HPMC isenokugcina ubunamatheko obulungileyo kunye ne-anti-i-anti-i-Anti-Sagring Propering phantsi kweemeko zobushushu obuphezulu.

Ukuphuculwa kwe-forlidality

Ngexesha lenkqubo yokumisa amaqondo obushushu, i-Microsture ye-HPMC ilungiselelwe, iyenza inyibilike kakhulu emanzini abandayo. Ingakumbi kwiindawo zokuhamba amaqondo obushushu asezantsi, i-HPMC inokukhawuleza inyibilikise kwaye yenze isisombululo se-colofal efanayo.

3. Ukusetyenziswa ngokuchanekileyo kwetekhnoloji yobushushu ephezulu kwinkqubo yemveliso ye-HPMC

Inqanaba lokuphendula lokuphendula

Ngokwenza i-etheristic yokuphendula kwiqondo lokushisa eliphezulu le-80-100 ° C, impendulo endaweni ye-hydroxypropy kunye namaqela e-methyl inokukhawuleziswa, ukuze i-HPMC inomgangatho ophezulu wokufaka endaweni yokufakelwa endaweni yokufakelwa.

Inqanaba elomileyo nelityhobozayo

Itekhnoloji yomisa ishushu ye-air ngaphezulu kwe-120 ° C ayinakususa umswakama, kodwa ikwathintela i-HPMC POMMDS ukusuka kwi-Ageglomerad ngexesha lenkqubo yokomisa. Emva koko, itekhnoloji yokutyumza kweqondo lokutyumza isetyenziselwa ukwenza amasuntswana e-HPMC Poples abuthathaka ngakumbi kwaye iyunifomu, kwaye ukusasazeka kwemveliso kuphuculwe.

Iqondo lobushushu ephezulu

Xa i-HPMC isetyenziswa kwizinto zokwakha okanye iingubo, unyango oluphezulu lonyango unokuluphucula ukunganyangeki kwe-rack, ukuchasana kwe-SAG kunye nokugcinwa kwe-SAG kunye nokugcinwa kwamanzi, ukuqinisekisa ukusebenza kakuhle kwiindawo ezinobunzima.

4. IINGXAKI ZOBUCHULE BENKCAZO YOBUCHULE KWI-HPMC SETY

Izinto zokwakha

Phantsi kwemeko yobushushu obuphezulu, i-HPMC ibonisa ukuqina okugqwesileyo kunye nokugcinwa kwamanzi kumda we-poker, ukuthintela i-tird ukusuka ngamanzi emzimbeni kunye nokuqhekeka.

Ishishini lokupeyinta

I-HPMC yahlulwe bubushushu obuphezulu inamanqanaba amahle kwaye i-Anti-i-Anting Gables kwipeyinti ye-Latex, ephucula umbilini, kwaye inxibe ukunganyangeki.

Ishishini lamachiza

Itekhnoloji yobushushu obuphezulu inokuphucula ukufana kwe-HPMC kwi-HPMC kwi-Ceating yeziyobisi kwaye iqinisekise uzinzo lwempembelelo.

Ukusetyenziswa kweTekhnoloji yobushushu ephezulu yehydroxypropyl methylcelceluploseAyiphuhli nje ukuphucula ukusebenza kakuhle kwemveliso, kodwa kukuphucula ukusebenza kwemveliso. Ngenkqubo yobushushu obuphezulu, i-viscosity, ukuntywila kunye nokuzinza kwe-HPMC kuye kwanelungelo kakhulu, kokwenza ukuba ifumane ithemba lesicelo esibanzi kwicandelo lokwakha, iingubo kunye namayeza. Kwixa elizayo, kunye nemveliso eqhubekayo yeTekhnoloji yobushushu obuphezulu, ukusebenza kwe-HPMC kuya kuqhubeka kuphuculwa, ukwenza iminikelo emikhulu kuphuhliso lwezixhobo eziluhlaza nezisingqongileyo.