Iimeko ezahlukeneyo zokusetyenziswa kufuneka zikhethe ii-viscosities ezahlukeneyo ze-cellulose HPMC

IHydroxypropylmethylcellulose (HPMC) yi-ether eselulosi ephuma kwimithombo yendalo efana nentlaka yeenkuni kunye ne-cotton linters. Ngenxa yeempawu zayo ezizodwa, kubandakanywa ukunyibilika kwamanzi, amandla okuqina, iipropati zokwenza ifilimu, njl., Isetyenziswa ngokubanzi kumashishini ahlukeneyo. Enye yezinto eziphambili ekufuneka ziqwalaselwe xa usebenzisa i-HPMC yi-viscosity yayo, enokuchaphazela kakhulu ukusebenza kwayo kwiindawo ezahlukeneyo zokusetyenziswa. Kweli nqaku, sixoxa ukuba kutheni i-cellulose HPMC ene-viscosities eyahlukileyo kufuneka ikhethwe kwiindawo ezahlukeneyo zokusetyenziswa, kunye nendlela i-viscosity echanekileyo inokunceda ngayo ukwandisa ukusebenza kwe-HPMC.

I-Viscosity ngumlinganiselo wokuchasa ulwelo ukuba uhambe kwaye luqwalaselo olubalulekileyo xa kuyilwa iimveliso ezifuna iimpawu ezithile zokuhamba. I-Viscosity ichaphazela ukusebenza kwe-HPMC kuba imisela amandla ayo okwenza iijeli, ezichaphazela i-pH yesisombululo, ubukhulu bengubo, kunye nezinye iimpawu zomzimba. I-HPMC ifumaneka kumabakala ahlukeneyo e-viscosity, ezona ntlobo zixhaphakileyo yi-viscosity ephantsi (LV), i-viscosity ephakathi (MV) kunye ne-viscosity ephezulu (HV). Nganye kwezi ntlobo zinenjongo ethile kwaye ifanelekile kwindawo ethile.

I-Viscosity ephantsi (LV) HPMC

I-viscosity ephantsi HPMC inobunzima obuphantsi bemolekyuli kwaye inyibilika ngokulula emanzini. Lolona hlobo luxhaphakileyo lwe-HPMC kwaye lusetyenziswa kwiintlobo ngeentlobo zemizi-mveliso kuquka ukutya, izithambiso, ulwakhiwo kunye namayeza. I-LV HPMC ifaneleke kakhulu kwizicelo ezifuna izisombululo ze-viscosity ezisezantsi ukuya eziphakathi ezifana neejeli ezicacileyo, i-emulsions kunye neepeyinti. I-LV HPMC ingasetyenziselwa ukwandisa ubomi beshelufu yokutya, ukunciphisa i-syneresis kunye nokubonelela nge-texture egudileyo.

I-LV HPMC ikwasetyenziswa rhoqo kushishino lokwakha ukuphucula ukusebenza kwemathiriyeli esekwe kwisamente efana nodaka, iigrouts kunye nokuncamatheliswa kweethayile. Inceda ukunciphisa ilahleko yamanzi kwimixube yesamente, ikhusela ukuqhekeka, kwaye iqinisa ibhondi phakathi kwezinto. I-LV HPMC ikwasetyenziselwa ukunyusa ukomelela kunye nokuqina kodaka, istucco kunye nezinye izinto ezinxulumeneyo.

I-Viscosity ePhakathi (MV) HPMC

I-viscosity ephakathi i-HPMC inobunzima bemolekyuli obuphezulu kune-LV HPMC kwaye ayinyibiliki kancinane emanzini. Ngokuqhelekileyo isetyenziswa kwizicelo ezifuna izisombululo ezigxininiswe ngakumbi ezifana neengubo, ivanishi kunye neenki. I-MV HPMC inolawulo olungcono lokuqukuqela kunye neempawu zesicelo kune-LV HPMC, ekhokelela kubukhulu obufanayo kunye nokuqina kwefilimu. I-MV HPMC ingasetyenziswa kuluhlu olubanzi lwe-pH, ibonelela ngezinto ezahlukeneyo ezongezelelweyo kwiinkqubo ezahlukeneyo.

I-MV HPMC isetyenziswa ngokubanzi kwiimveliso zamachiza, ezifana neepilisi zokukhululwa ezilawulwayo, njengoko zilibazisa ukutshatyalaliswa kwaye ngaloo ndlela kwandisa ukukhutshwa kwezithako ezisebenzayo.

Viscosity High (HV) HPMC

I-viscosity ephezulu HPMC inobunzima obuphezulu bemolekyuli kuwo onke amabakala amathathu kwaye yeyona incinci inyibilikayo emanzini. Idla ngokusetyenziswa kwizicelo ezifuna ukujiya kunye nokuzinzisa iipropathi, ezinje ngeesosi, iikhrimu kunye neegels. I-HV HPMC inceda ukuphucula ukuthungwa kunye ne-viscosity yeemveliso, ibonelela ngamava omsebenzisi amnandi ngakumbi. Ingasetyenziselwa ukuzinzisa i-emulsions, ukukhusela ukuhlala kunye nokwandisa ubomi beshelufu. Ukongeza, i-HV HPMC ihlala isetyenziswa kushishino lwephepha ukuphucula amandla ephepha kunye nokuprintwa.

ukuququmbela

I-viscosity echanekileyo ye-HPMC ibalulekile ukunyusa ukusebenza kwayo kwiindawo ezahlukeneyo zokusetyenziswa. I-LV HPMC ifaneleka kakhulu kwizicelo ezifuna izisombululo ze-viscosity ezisezantsi ukuya eziphakathi, ngelixa i-MV HPMC ilungele izisombululo ezityebileyo ezifana neepeyinti, ivanishi kunye neenki. Okokugqibela, iHV HPMC ilungele usetyenziso olufuna ukujiya kunye nokuzinzisa iipropathi ezinjengeekhrimu, iijeli kunye neesosi. Ukukhetha i-viscosity echanekileyo inokunceda ukuphucula ukusebenza ngokubanzi kwe-HPMC kwaye iyenze ifaneleke ngakumbi kwizicelo ezahlukeneyo.