I-Hydroxypropylmethylcelcelcelcelcelcelcelcelcelcelcelcebalose (i-HPMC) yi-computer ebiyibambile kwizinto eziphezulu kumashishini amaninzi ngenxa yepropathi yabantu. Iqhelekile isetyenziswa njengokutya, i-thichoner kwizithako, kunye nesithako sonyango kumayeza amaninzi. Ipropathi eyahlukileyo ye-HPMC yindlela yayo yokuziphatha, evumela ukuba itshintshe i-viscofity kunye neepropathi zokuhamba phantsi kweemeko ezithile. Ukongeza, zombini i-viscofity ephezulu kunye ne-HPMC ye-HPMC ye-HPMC inayo le propati, ibonisa i-Thtringitropy naphantsi kweqondo lobushushu.
I-ThixotRopy yenzeka kwi-HPMC xa isisombululo sithi shear-sitsing xa uxinzelelo lusetyenziswa okanye luvuseleleke, lukhokelela ekunciphiseni kwe-vickosity. Oku kuziphatha kunokubuyiselwa umva; Xa uxinzelelo lususiwe kwaye isisombululo sishiywe ukuba siphumle, i-viscosity ibuyela kancinci kwimeko yayo ephezulu. Le ndawo yodwa yenza i-HPMC i-HPMC ibaluleke kakhulu kumashishini amaninzi njengoko ivumela isicelo se-Fousost kwaye isebenza lula.
Njengomnxeba we-hydrocolloid, i-HPMC ishushu emanzini ukwenza ijeli. Inqanaba lokudumba kunye nokugcwala kuxhomekeke kubunzima bemolekyuli kunye nokugxininiswa kwePolymer, i-PH kunye neqondo lokushisa lesisombululo. I-Vilosity ephezulu ye-HPMC iqhele ukuba nobunzima obuphezulu kwaye ivelise ijeli ephezulu ye-viscofity, ngelixa i-HPMC ephantsi ye-HPMC ine-molecular ephantsi kwaye ivelise ijeli engaphantsi. Nangona kunjalo, ngaphandle kwale misebenzi ekusebenzeni, zombini iintlobo ze-HPMCS i-ThPMCOP ye-TIiXOTROP YOKUGQIBELA EYENZA kwinqanaba le-molecular.
Ukuziphatha kwe-thmmc ye-HPMC sisiphumo solungelelwaniso lwamakhonkco ePolymer ngenxa yoxinzelelo lwe-Shear. Xa uxinzelelo lwe-Shear lusetyenziswa kwi-HPMC, imixokelelwane yePolymer iguqulela kwicala loxinzelelo oluthengisiweyo, olukhokelela ekutshatyalalisweni kolwakhiwo lwenethiwekhi ezintathu ezazikho kuxinzelelo. Ukuphazamiseka kwenethiwekhi kukhokelela ekunciphiseni kwesisombululo. Xa uxinzelelo lususiwe, amakhonkco ePolymer ahlengahlengise ekuziqhelaniso kwabo, ukwakha inethiwekhi kunye nokubuyisela i-viscofity.
I-HPMC ikwabonisa i-Thiyotropy ingezantsi kweqondo lobushushu. Iqondo lobushushu le-gel liqondo lobushushu apho ikhonkco le-polymer enqunyamisayo ukuze ilungiswe inethiwekhi emithathu, yenze ijeli. Kuxhomekeka kubunzima, ubunzima bemolekyuli kunye ne-pH yesisombululo sePolymer. Ijeli ebangela i-viskosity ephezulu kwaye ayitshintshi ngokukhawuleza phantsi koxinzelelo. Nangona kunjalo, ngezantsi kweqondo lobushushu, isisombululo se-HPMC sahlala ulwelo, kodwa sabonakalisa indlela yokuziphatha ye-Thixic yeThokotropic ngenxa yobukho bendlela yenethiwekhi. Inethiwekhi eyenziwa ngala malungu ayikhathisi phantsi koxinzelelo, ngenxa yokuncipha kwe-viscosity. Oku kuziphatha kuyingenelo kwizicelo ezininzi apho izisombululo kufuneka zihambe ngokulula xa zivuselelekile.
I-HPMC yindawo yokuqulunqa iikhemikhali ezifanayo kunye neepropathi ezininzi ezahlukileyo, enye yazo yindlela yayo yokuziphatha. Zombini i-viscosity ephezulu kunye nee-HPMCs eziphantsi ze-HPMSs zinepropathi, zibonisa i-Thmiotropy naphantsi kweqondo lobushushu. Olu phawu lwenza i-HPMC Inxalenye ebalulekileyo kumashishini amaninzi afuna izisombululo eziphatheka ngokulula ukuqinisekisa isicelo esigudileyo. Ngaphandle komahluko kwipropathi ephakathi kwe-viscofity ephezulu kunye ne-HPMCS ephantsi, indlela yabo yeThixitropic yenzeka ngenxa yolungelelwaniso kunye nokuphazamiseka kwenethiwekhi yenethiwekhi. Ngenxa yeepropathi zayo ezizodwa, abaphandi bahlala bevavanya ukusetyenziswa kwezicelo ezahlukeneyo ze-HPMC, benethemba lokudala iimveliso ezintsha kwaye banike izisombululo ezingcono zabathengi kwihlabathi liphela.
IXESHA LOKUQALA: Aug-23 ukuya kwi-2023