I-Hydroxyethyl cellulose (HEC) i-non-ionic, i-polymer enyibilikayo emanzini ephuma kwi-cellulose. Isetyenziswa kakhulu kumashishini ahlukeneyo, kubandakanywa izinto zokuncamathelisa, apho isebenza njenge-agent yokuqina, i-rheology modifier, kunye ne-stabilizer. Ikhono le-HEC lokuphucula i-viscosity ye-adhesives ibaluleke kakhulu kwizicelo ezininzi, ukuqinisekisa ukusetyenziswa okufanelekileyo, ukusebenza, kunye nexesha elide lemveliso yokubambelela.
Iipropati zeHydroxyethyl Cellulose
I-HEC iveliswa ngokuphendula i-cellulose nge-ethylene oxide phantsi kweemeko ze-alkaline, okubangela ukuba i-polymer kunye namaqela e-hydroxyethyl afakwe kwi-backbone ye-cellulose. I-degree of substitution (DS) kunye ne-molar substitution (MS) ziiparamitha eziphambili ezichaphazela iipropati ze-HEC. I-DS ibhekiselele kumyinge wenani lamaqela e-hydroxyl kwimolekyuli ye-cellulose efakwe endaweni yamaqela e-hydroxyethyl, ngelixa i-MS ibonisa inani eliphakathi kwee-moles ze-ethylene oxide eziye zasabela nge-mole enye yeeyunithi ze-anhydroglucose kwi-cellulose.
I-HEC ibonakala ngokunyibilika kwayo emanzini, ukwenza izisombululo ezicacileyo kunye nezicacileyo kunye ne-viscosity ephezulu. I-viscosity yayo iphenjelelwa zizinto ezininzi, kubandakanya ubunzima bemolekyuli, ukugxininiswa, ubushushu, kunye ne-pH yesisombululo. Ubunzima be-molecular ye-HEC bunokuqala ukusuka kwi-low ukuya phezulu kakhulu, ukuvumela ukuqulunqwa kwe-adhesives ngeemfuno ezahlukeneyo ze-viscosity.
Iindlela zokuPhucula iViscosity
Ukufakwa kwamanzi kunye nokuDumba:
I-HEC iphucula i-viscosity enamathelayo ngokuyintloko ngokukwazi kwayo ukuhambisa amanzi kunye nokudumba emanzini. Xa i-HEC yongezwa kwi-adhesive formulation formlation, amaqela e-hydroxyethyl atsala iamolekyu zamanzi, ezikhokelela ekudumbeni kwamakhonkco e-polymer. Oku kudumba kwandisa ukuxhathisa kwesisombululo ukuhamba, ngaloo ndlela kwandisa i-viscosity yayo. Ubungakanani bokuvuvukala kunye ne-viscosity ebangelwayo ithonywe yi-polymer concentration kunye ne-molecular weight ye-HEC.
Ukubanjiswa kweMolekyuli:
Kwisisombululo, iipolymers ze-HEC zingena entanglement ngenxa yesakhiwo sazo sekhonkco elide. Oku kudibanisa kudala inethiwekhi ethintela ukuhamba kweeathomu ngaphakathi kwe-adhesive, ngaloo ndlela ikhulise i-viscosity. Ubunzima bemolekyuli ephezulu ye-HEC ibangela ukubanjiswa okubaluleke ngakumbi kunye ne-viscosity ephezulu. Iqondo lokungena liyakwazi ukulawulwa ngokulungelelanisa i-polymer concentration kunye ne-molecular weight ye-HEC esetyenzisiweyo.
Ukudityaniswa kweHydrojeni:
I-HEC inokwenza iibhondi ze-hydrogen kunye neemolekyuli zamanzi kunye nezinye iinqununu kwi-adhesive formulation. Ezi bhondi ze-hydrogen zifaka isandla kwi-viscosity ngokudala inethiwekhi eyakhiwe ngakumbi ngaphakathi kwesisombululo. Amaqela e-hydroxyethyl kumqolo we-cellulose aphucula amandla okwenza iibhondi ze-hydrogen, ukwandisa ngakumbi i-viscosity.
Ukuziphatha kokucheba:
I-HEC ibonisa ukuziphatha kwe-shear-thinning, oku kuthetha ukuba i-viscosity yayo iyancipha phantsi koxinzelelo lwe-shear. Le propati inenzuzo kwizicelo zokubambelela kuba ivumela isicelo esilula phantsi kwe-shear (efana nokusabalalisa okanye ukuxubha) ngelixa ugcina i-viscosity ephezulu xa uphumle, uqinisekisa ukusebenza kakuhle kunye nokuzinza. Ukuziphatha kwe-shear-thinning ye-HEC kubangelwa ukulungelelaniswa kwamaketanga e-polymer kwicala lokusetyenziswa kwamandla, ukunciphisa ukuchasana kwangaphakathi okwethutyana.
Izicelo kwiiFomu zokuncamathelisa
Izinto zokuncamathelisa ezisekelwe emanzini:
I-HEC isetyenziswa kakhulu kwizinto zokuncamathelisa ezisekwe emanzini, ezifana nezo zephepha, zamalaphu nezomthi. Ikhono layo lokunyusa kunye nokuzinzisa ukubunjwa kwe-adhesive iqinisekisa ukuba ihlala ixutywe ngokufanayo kwaye kulula ukuyisebenzisa. Kwiphepha kunye ne-adhesives yokupakisha, i-HEC ibonelela nge-viscosity efunekayo kwisicelo esifanelekileyo kunye namandla okudibanisa.
Izinto ezincamathelayo zokwakha:
Kwizinto ezinamathele zokwakha, ezifana nezo zisetyenziselwa ukufakwa kweetayile okanye ukugubungela udonga, i-HEC iphucula i-viscosity, iphucula ukusebenza kwe-adhesive kunye nokuxhatshazwa kwe-sag. Isenzo sokuqina se-HEC siqinisekisa ukuba i-adhesive ihlala kwindawo ngexesha lesicelo kwaye ibeka ngokufanelekileyo, inika ibhondi eqinile kunye neyomelele.
Izinto zokuzihombisa kunye nezoNonophelo loBuqu:
I-HEC ikwasetyenziswa kwiimveliso zokuthambisa kunye nezokukhathalela zobuqu ezifuna iipropathi zokuncamathelisa, ezinje ngeegel zesitayile seenwele kunye nemaski yobuso. Kwezi zicelo, i-HEC ibonelela ngokungaguquguqukiyo kunye nokufana okufanayo, ukuphucula ukusebenza kwemveliso kunye namava omsebenzisi.
Izinto zokuncamathelisa zamayeza:
Kumashishini amayeza, i-HEC isetyenziswa kwiipatches ze-transdermal kunye nezinye iinkqubo zokuhanjiswa kweziyobisi apho i-viscosity elawulwayo ibalulekile ekusebenzeni kwe-adhesive. I-HEC iqinisekisa ukuba i-adhesive layer ifana, inika ukuhanjiswa kweziyobisi okuhambelanayo kunye nokuthotyelwa kwesikhumba.
Izinto ezichaphazela ukuphuculwa kwe-Viscosity
Ugxininiso:
Ukuxinwa kwe-HEC kwi-adhesive formulation ihambelana ngokuthe ngqo kwi-viscosity. Ugxininiso oluphezulu lwe-HEC lubangela ukwanda kwe-viscosity ngenxa yentsebenziswano ebalulekileyo ye-polymer chain kunye ne-entanglement. Nangona kunjalo, ukugxila okuphezulu kakhulu kunokukhokelela kwi-gelation kunye nobunzima bokucubungula.
Ubunzima beMolekyuli:
Ubunzima be-molecular ye-HEC yinto ebalulekileyo ekunqumeni i-viscosity ye-adhesive. Ubunzima bemolekyuli ephezulu ye-HEC ibonelela nge-viscosity ephezulu kwiindawo ezisezantsi xa kuthelekiswa nokwahluka kobunzima bemolekyuli. Ukukhethwa kobunzima be-molecular kuxhomekeke kwi-viscosity efunwayo kunye neemfuno zesicelo.
Ubushushu:
Ubushushu buchaphazela i-viscosity yezisombululo ze-HEC. Njengoko iqondo lokushisa lisanda, i-viscosity iyancipha ngenxa yokunciphisa i-hydrogen bonding kunye nokunyuka kokuhamba kweemolekyuli. Ukuqonda ubudlelwane beqondo lokushisa kunye ne-viscosity kubalulekile kwizicelo ezivezwe kumaqondo okushisa ahlukeneyo.
pH:
I-pH ye-adhesive formulation inokuchaphazela i-viscosity ye-HEC. I-HEC izinzile kuluhlu olubanzi lwe-pH, kodwa iimeko ezigqithisileyo ze-pH zingakhokelela ekutshintsheni kwisakhiwo sepolymer kunye ne-viscosity. Ukuqulunqa i-adhesives ngaphakathi koluhlu lwe-pH olufanelekileyo luqinisekisa ukusebenza okufanayo.
Izinto eziluncedo zokusebenzisa iHydroxyethyl Cellulose
Indalo engeyiyo ye-Ionic:
Ubume be-HEC obungeyona i-ionic buyenza ihambelane noluhlu olubanzi lwamanye amacandelo okuqulunqa, kubandakanywa nezinye iipolymers, i-surfactants, kunye ne-electrolytes. Oku kuhambelana kuvumela ukuxutywa kwezinto ezininzi zokuncamathelisa.
Ukonakala kwezinto eziphilayo:
I-HEC ithathwe kwi-cellulose, isibonelelo sendalo kunye nokuhlaziywa. I-biodegradable, iyenza ibe lukhetho oluhambelana nokusingqongileyo kwimiqulu yokuncamathelisa. Ukusetyenziswa kwayo kuhambelana nemfuno ekhulayo yeemveliso ezizinzileyo kunye ne-eco-friendly.
Uzinzo:
I-HEC inika uzinzo olugqwesileyo kwiifom ze-adhesive, ukuthintela ukuhlukana kwesigaba kunye nokuhlaliswa kwezinto eziqinileyo. Olu uzinzo luqinisekisa ukuba i-adhesive ihlala isebenza kuyo yonke ishelufu yayo kunye nexesha lokusetyenziswa.
Iinkcazelo Ngeempawu Zokwenza Umboniso bhanyabhanya:
I-HEC yenza iifilimu eziguquguqukayo kunye nezicacileyo xa zomiswe, eziluncedo kwizicelo zokubambelela ezifuna umgca webhondi ocacileyo kunye oguquguqukayo. Le propati iluncedo kakhulu kwizicelo ezifana neeleyibhile kunye neeteyiphu.
I-Hydroxyethyl cellulose idlala indima ebalulekileyo ekwandiseni i-viscosity yezinto ezincamathelayo ngokusebenzisa iindlela ezinje ngehydration kunye nokudumba, ukubanjiswa kwemolekyuli, ukubopha i-hydrogen, kunye nokuziphatha okuchetywayo. Iipropathi zayo, kubandakanya ukunyibilika, ubume be-non-ionic, i-biodegradability, kunye nobuchule bokwenza ifilimu, buyenza ibe lolona khetho lufanelekileyo kwiinkqubo ezahlukeneyo zokuncamathelisa. Ukuqonda izinto ezichaphazela ukuphuculwa kwe-viscosity ye-HEC, njengokugxininiswa, ubunzima bemolekyuli, ubushushu, kunye ne-pH, ivumela abaqulunqi ukuba benze iimveliso zokunamathela ukuze zihlangabezane neemfuno ezithile zokusebenza. Njengoko amashishini aqhubeka efuna izinto ezizinzileyo kunye nokusebenza okuphezulu, i-HEC ihlala iyinxalenye ebalulekileyo ekuqulunqweni kweemveliso zokubambelela eziphambili.
Ixesha lokuposa: May-29-2024