I-HPMC isetyenziswa njengokucofa amayeza

Hydroxypropyl methylcelculose (hpmc)isetyenziswa njengenye yezona zinto zinkulu zamayeza ekhaya kunye nasephesheya. I-HPMC inokusetyenziswa njengearhente yefilimu, iarhente yokukhupha, i-orhente yokukhutshwa, iarhente yokumiselwa, i-Enulsifier, iarhente ye-ensultiver

I-EMARMUCEIL Inxalenye ebalulekileyo yamalungiselelo ngamayeza, kunye nendima yabo kukuqinisekisa ukuba iziyobisi zithuthelwa ngokuzithandela kwizicube ngendlela ethile kunye nexesha. Ke ngoko, ukukhetha kwabo banomdla kwenye yezona zinto zibalulekileyo zefuthe lonyango lwamalungiselelo amachiza amayeza.

I-1 yeepropathi ze-HPMC

I-HPMC ineempawu ezininzi ezinye iziqu ezinganayo. Inamandla amakhulu okulala kwamanzi kumanzi abandayo. Ngalo lonke ixesha longezwa kumanzi abandayo kwaye ivuse kancinci, inokunyibilikisa isisombululo esibonakalayo. Ngokuchasene noko, ngokusisiseko i-infliness kumanzi ashushu ngaphezulu kwe-60E kwaye inokunyibilikisa kuphela. Ngaba i-ionic ye-ionsulose i-ether, isisombululo sayo asinayo i-ionic ye-ionic, kunye neetyuwa zentsimbi okanye i-ionic ye-organic okanye i-ionic yendalo, ukuze iqinisekise ukuba i-HPMC ayisabelanga kwezinye izinto zokulungiselela. Ngemvakalelo enamandla e-anti-imvakalelo, kunye nokunyuka kwemozulu ye-molecular yenqanaba lokufakwa, i-anti-defaitic kuyahambelana neziyobisi, i-starch, i-Dextrin, i-Dextrade, ixesha elisebenzayo lizinzile. IneTetabolic ineera. Njengezinto ezincedisayo zamayeza, ayinakukwazi ukubekwa i-metabollid okanye ingene, ngenxa yoko ayiboneleli ngekhalori kunyango kunye nokutya. Inokwenziwa okwahlukileyo kwexabiso le-caloritic elisezantsi, amayeza anetyiwa kunye nokungasebenzi kakuhle kunye nokutya okufuneka abantu abaneswekile. I-HPMC izinzile kakhulu kwi-acid kunye ne-alkali, kodwa ukuba iyadlula i-Ph2 ~ 11 kwaye iphantsi kobushushu obuphezulu okanye ixesha lokugcina lide, i-vickosity iya kuncitshiswa. Isisombululo esinamandla sinika umsebenzi owomgangatho kwaye siveze imbambano yomphezulu ophakathi kunye namaxabiso ahlanganisiweyo. Inesigwebo esisebenzayo kwinkqubo yesigaba sesibini kwaye inokusetyenziswa njengesiqhelo kunye ne-colloid ekhuselweyo. Isisombululo se-ACTEACE Inemilimi ebalaseleyo yefilimu yeli filimu kwaye sisixhobo esihle sokuhamba kweetafile kunye neepilisi. Ifilimu eyenziwe yiyo ayinantsingiselo kwaye inzima. Iplasitika yayo ingekanyuswa ngokongeza i-glycerol.

2.Ukusebenza kwe-HPMC kwimveliso yetafile

2.1 Ukuphucula ukuchithwa

Usebenzisa isisombululo se-HPMC Ethanol okanye isisombululo se-AIRTE NERUND YOKUGQIBELA YOKUGQIBELA, Ukuphucula ukuchithwa kweetafile, impembelelo iyaphawuleka, kwaye icinezelwe ukuba ilunge kakhulu, inkangeleko egudileyo. I-Solubing yeTayitile yeRenimodipine: Ukunyibilisela kwe-17.84% ye-ethanol, i-5% ye-Ethanol ye-Ethanol ye-Ethanol ye-Ethanol ye-Ethanol ye-Ethanol, i-3% ye-HPMC, i-5% ye-HPMC, i-5% ye-HPMC, i-5% ye-HPMC, i-5% ye-HPMC, i-5% ye-HPMC, i-5% ye-HPMC, i-5% ye-HPMC, i-5% Isisombululo se-HPMC, ngokwahlukeneyo. 30.84%, 75.46%, i-84.5%, 88%. Ireyithi yokuchithwa kweepilisi ze-pihodi: Xa ukunamathela kwi-12% ye-ethanol, i-HPMC (40% ye-HPMC, i-HPMC (40% ye-HPMC (i-HPMC), 99.88%, ngokulandelelana. Izinga lokuchithwa kweepilisi ze-cimetidine: Xa i-adhestive ibili-10% starch slickry kunye ne-3% ye-HPMC (40%), ireyithi ye-ETHMC, ireyithi ye-ETHME yayingama-78.54%, ngokulandelelana.

Ukusuka kule datha ingentla, inokubonwa ukuba isisombululo se-Ethanol kunye nesicombululo se-HPMC sinefuthe lokuphucula ukuchitheka kweziyobisi, enokunciphisa uxinzelelo oluphakathi phakathi kwesisombululo kunye nokuchitheka kweziyobisi.

2.2 Ukuphucula umgangatho wokudibana

I-HPMC njengendawo yokwakha ifilimu, xa kuthelekiswa nezinye izinto ezenziweyo zefilimu (i-Acryclic Redeen, Polythylene Pylolidone), eyona nto ibalulekileyo kukuzithoba kwamanzi, ayidingi zizinto eziphilayo, ezisebenzayo. KwayeI-HPMCIneentlobo ngeentlobo zeendlela zokubonisa ukufakwa, ukhetho olufanelekileyo, olunemigangatho yefilimu, imbonakalo ingcono kunezinye izinto. I-CIPROFLOGACINCY HYDROCHide itafile ezimhlophe zetafile ezinamacala amabini. Ezi pilisi zefilimu ezinqabileyo zinzima, ngokulinganayo, khetha i-viscosity yepilisi yefilimu, i-oyile, i-oyile, i-oyile, i-oyile, i-oranges, i-ored, iqaqambile. Xa kuthelekiswa nolwelongo lwendabuko, lo mthetho ulula kwaye unengqiqo, kwaye iindleko zincitshisiwe kakhulu.