I-Hydroxypropyl methyl cellulose kunye ne-carboxymethyl cellulose sodium inokuxutywa

Ngaba HPMC kunye CMC mix

I-Methyl celluloseimhlophe okanye imhlophe njenge-fibrous okanye i-granular powder; Ayinavumba, ayinancasa. Le mveliso ekudumbeni kwamanzi kwisisombululo esicacileyo okanye esincinci se-colloidal; Ayinyibiliki kwi-ethanol epheleleyo, i-chloroform okanye i-diethyl ether. Isasazwa ngokukhawuleza kwaye idumbe emanzini ashushu kwi-80-90 ℃, kwaye inyibilika ngokukhawuleza emva kokupholisa. Isisombululo se-aqueous sizinzile kwiqondo lokushisa, kwaye siyakwazi i-gel kwiqondo lokushisa eliphezulu, kwaye i-gel inokutshintsha kunye nesisombululo kunye nobushushu.

Inobumanzi obugqwesileyo, ukusabalalisa, ukunamathela, ukuqina, i-emulsification, ukugcinwa kwamanzi kunye nokwakheka kwefilimu, kunye nokungangeni kweoli. Ifilimu inokuqina okubalaseleyo, ukuguquguquka kunye nokungafihli. Ngenxa yokuba i-non-ionic, inokuhambelana nezinye i-emulsifiers, kodwa kulula ukuyicoca ityuwa, kwaye isisombululo sizinzile kuluhlu lwe-PH2 - 12. I-sodium carboxymethyl cellulose Le mveliso ityuwa yesodium ye-cellulose carboxymethyl ether, yeye-anionic cellulose ether, imhlophe okanye i-milky white fibrous powder okanye isuntswana, ubuninzi be-0.5-0.7 g/cubic isentimitha, phantse ivumba, incasa, ihygroscopic. Kulula ukusasaza emanzini kwisisombululo segelatinous esicacileyo, esinganyibiliki kwi-ethanol kunye nezinye izinyibilikisi eziphilayo.

Xa i-pH yesisombululo se-aqueous i-6.5 - 8.5, i-viscosity ye-slurry iyancipha kakhulu xa i-pH i> 10 okanye <5, kwaye ukusebenza kuyona nto ibhetele xa i-pH i-7. Ukuzinza kwe-thermal, i-viscosity iphakama ngokukhawuleza ngaphantsi. I-20 ℃, itshintsha kancinci kwi-45 ℃, kwaye i-colloid denaturation kunye ne-viscosity kunye neempawu zehla kakhulu xa ushushu ixesha elide. ngaphezulu kwe80℃. Inyibilika ngokulula emanzini, isisombululo esicacileyo; Izinzile kakhulu kwisisombululo se-alkaline, kwaye kulula ukwenza i-hydrolyze kwimeko ye-asidi. Xa ixabiso le-pH liyi-2-3, imvula iya kwenzeka, kwaye imvula iya kwenzeka nakwimeko yeetyuwa zetsimbi ezininzi. IHydroxypropyl methyl cellulose, ekwabizwa ngokuba yi-hydroxypropyl methyl cellulose, i-cellulose hydroxypropyl methyl ether, kukukhethwa kweselulosi yomqhaphu esulungekileyo kakhulu njengesixhobo ekrwada, phantsi kweemeko ze-alkaline ngokufakwa okukhethekileyo kunye nokulungiswa.

I-Soluble emanzini kunye ne-polar C eninzi kunye nomlinganiselo ofanelekileyo we-ethanol / amanzi, ipropanol / amanzi, i-dichloroethane, njl., enganyibilikiyo kwi-diethyl ether, i-acetone, i-ethanol epheleleyo, ukudumba emanzini abandayo kwisisombululo se-colloidal esicacileyo okanye esincinci. Isisombululo samanzi sinomsebenzi ongaphezulu, ukukhanya okuphezulu kunye nokusebenza okuzinzileyo.HPMCinepropati yejeli eshushu. Emva kokufudumeza, isisombululo se-aqueous yemveliso senza i-gel precipitation, kwaye sinyibilike emva kokupholisa. Ubushushu bejeli beenkcukacha ezahlukeneyo buhlukile.