Hydroxypropyl methyl seluplose njengokuthanda amayeza

Hydroxypropyl methyl seluplose (hpmc)Ngaba i-phamacelee phamacelical inomdla kakhulu kwiifom ezahlukeneyo zedosi ngenxa yepropathi eyahlukileyo. Esi sixhobo se-seluplose sivela kwi-seluplose, ipolly yemvelo eyenzeka ngokwemvelo ifumaneka kwizityalo, kwaye iguqulwe ngokuphendula kweekhemikhali ukufumana iimpawu ezinqwenelekayo. Kumachiza amayeza, i-HPMC isebenzela imisebenzi emininzi, kubandakanya i-binder, ifilimu yangaphambili, i-thickener, i-stibkener, kunye ne-Arhente egciniweyo. Isicelo sayo esibanzi kunye nokubaluleka kwishishini lamayeza Ukuqonda okubanzi kweepropathi, izicelo kunye nezibonelelo.

I-HPMMC's Solity kunye neepropathi ze-viscosity zenza ukuba lukhetho oluhle lokulawula ukukhutshwa kweziyobisi kwiifom zethamo eziqinileyo zomlomo. Iyenza i-gel matrix kwi-hydration, ekwazi ukugcina ukukhutshwa ngamachiza ngokukhutshwa kwe-gel gel gel. I-viscosity yejeli ixhomekeke kwizinto ezinje ngobunzima bemolekyuli, isidanga sokufakwa endaweni, kunye nokugxininiswa kwe-HPMC ekuqulunqweni. Ngokutshintsha kwezi paramitha, izazinzulu zamayeza zinokulinganisa iiprofayili zokukhululeka iziyobisi ukufezekisa iziphumo ezinqwenelekayo, njengokukhululwa kwangoko, ukukhutshwa okuzinzileyo.

I-HPMC idla ngokusetyenziswa njenge-binder kwifomu yecwecwe ukudlulisela ukubambelela kunye nokuphucula amandla eetafile. Njengomthi we-binder, ikhuthaza amachaphaza amachaphaza ngexesha lenkqubo yokucinezelwa kwetafile, ikhokelela kwiitafile ezinomxholo weziyobisi ofanayo kunye neeprofayili ezingapheliyo. Ukongeza, iipropathi zokwenza ifilimu ze-HPMC zenza ukuba ilungele iitafile zokuhlalisa, ezisebenza ngeenjongo ezahlukeneyo ezinjengokuthintela imaski, ukukhuselwa komswakama, kunye nokukhutshwa kweziyobisi.

Ukongeza kwiifom zomlomo oqinileyo, i-HPMC ifumana isicelo kwezinye iindlela zamayeza, kubandakanya izisombululo ze-Ophthalmic, ii-pils eziphezulu, ii-pilsdical pires, kunye nokukhupha okulawulwa kwezinto. Kwizisombululo ze-Ophthalmic, i-HPMC isebenza njenge-Aryesity-yokuphucula ixesha lokuhlala, ukuphucula ixesha lokuhlala lokuqulunqwa komgangatho we-Ocular kunye nokuphucula ukufunwa kweziyobisi. Kwii-genes eziphezulu, ibonelela ngolawulo lwe-rublogical, ivumela ukusetyenziswa ngokulula kunye nokuphucula ukungena kwesikhumba kwezithako ezisebenzayo.

I-HPMCIipakethi zenguqu esekenziniweyo zibonelela ngenkqubo efanelekileyo yokuhambisa iziyobisi nengahlaseliyo yenkqubo yeziyobisi okanye i-suby yonyango lwasekhaya. I-polymer matrix ilawula ukukhutshwa iziyobisi ngolusu ngaphezulu kwexesha elongeziweyo, ukugcina amanqanaba onyango kwigazi kwigazi legazi ngelixa kuguqulwa ukuguquguquka. Oku kuyingenelo ikakhulu kubayobisi ngeewindows ezinqabileyo okanye abo bafuna ulawulo oluqhubekayo.

I-HPMMC's Biomitibukayo kunye ne-Intertury zenza kufanelekile ukuba zisetyenziswe kwifomu elingaqhelekanga njenge-arhente yokumisa okanye i-viscosity modifier. Kwi-Init-Khupha i-Initables, i-HPMC Imicrossores okanye i-nanopalicles ingenisa iimolekyuli zeziyobisi, ukubonelela ngokukhululwa okuzinzileyo ngexesha elongezelelweyo, ngaloo ndlela kuncitshiswa ukuthotyelwa kwe-dosing kunye nokuphucula ukuthotyelwa kwesigulo.

I-HPMC ibonisa iipropathi ze-MucoAxakee, iyenza iluncedo kwizinto ezenziweyo ezenzelwe ukuhanjiswa kweziyobisi, ezinjengeefilimu zefilimu kunye neefilimu zempumlo. Ngokunamathela kwimiba ye-mucosal, i-HPMC ye-HPMC yoSongs ixesha lokuhlala, ivumela ukwaphuculwa kweziyobisi kunye nokuzifumana kufundiswayo.

I-HPMC iqatshelwe ngokubanzi njengezisemagunyeni ezilawulayo ezinjengeendlela zokutya kunye nolawulo lweziyobisi (i-FDA), zenza ukuba zilungele ukusetyenziswa kwabantu. Imeko yayo yayo yengqondo kunye netyhefu yetyhefu iqhuba igalelo kwisibheno sayo njengokuthanda amayeza.

Hydroxypropyl methyl seluplose (hpmc)Ngaba iyeza lezinto ezenziwa ngokuguquguqukayo kunye nezicelo ezahlukeneyo kwiifom ezahlukeneyo zedosi. Iipropathi zayo ezizodwa, kubandakanya ukungcungcutheka, i-viscosity, ubuchule bokwenza ifilimu, kunye nokuzibandakanya, zenza ukuba ibe yinto engenakuphikwa kwe-biomity, yenza ukuba ibe yinto engenakuphikwa kwe-biomatives kwiNkqubo ethile yoThengiso. Njengoko uphando lwamayeza luyaqhubeka nokuvela, i-HPMC inokwenzeka ukuba ihlale ilitye lezimbo ukuba ithande ukuqulunqwa kweenkqubo zokuhambisa amachiza kunye nefom.