Hydroxypropyl methylcelcelcelse modeliment memodeli

Hydroxypropyl methylcelculose (hpmc)yindawo eguquguqukayo esetyenziswa kumashishini ahlukeneyo, kubandakanya amayeza, ukutya, amayeza kunye nolwakhiwo. Iipropathi zayo kunye nezicelo ziyahluka ngokuxhomekeka kwisakhiwo sayo semolekyuli, esinokuguqulwa ukuba sihambelane neemfuno ezithile.

Isakhiwo sekhemikhali:

I-HPMC yindawo yokukhutshwa kwe-seluplose, i-polymer yendalo efumaneka kwizityalo.
I-hydroxypropy ye-hydropyl kunye ne-methyl mpahla iqhotyoshelwe kumaqela e-hydroxyl yendawo yasellecelose.
Umyinge wale nto ubeka iipropathi ze-HPMC, ezinjengokungabizi, ukungqubana, kunye nobuchule bokwenza ifilimu.

Isidanga sokufaka (DS):

I-DS ibhekisa kwinani eliqhelekileyo lamaqela athabathelayo kwiyunithi ye-glucose nganye kwi-selsulose backbone.
Iimpawu eziphakamileyo ze-DS zikhokelela ekunyukeni kwe-hydrophicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicicility, ukuzolula, kunye namandla okuba.
I-DS ye-DS HPMC iZiziseko kakhulu kwaye inesibindi sokunganyangwa ngakumbi, sisenza ilungele izicelo kwizixhobo zokwakha.

Ubunzima beMolekyuli (MW):

Ubunzima bemolekyuli buchaphazela i-viscofity, amandla okwenza ifilimu, kunye neepropathi zoomatshini.
I-HPMURE ephezulu yemolekyuli iqhelekileyo ine-viscofity ephezulu kunye neepropathi ezingcono zefilimu, ezenza ukuba ilungele ukusetyenziswa kwifomu lezityalo ezinzileyo.
I-molecular yemolekyuli yemolekyuli ikhethiwe kwizicelo apho i-viscosity esezantsi kwaye icinyiwe ngokukhawuleza, njengeengubo zangaphantsi kunye nemibhede.

Ubungakanani bentsundu:

Ubungakanani bentsumpa ifuthe kwiPropathi yePowder, inqanaba lokuSolisa, kunye nokufana kwifomu.
Ubungakanani obuhle be-HPMC busasazeka ngokulula kwizisombululo ze-aquecte, ezikhokelela ekuqulunqweni kwe-hydrations ngokukhawuleza kunye nokwakha igel.
Amasuntswana e-Coarder anokubonelela ngeepropathi zokuhamba ezingcono kwimixube eyomileyo kodwa inokufuna amaxesha amade ombane.

Ubushushu be-Genco

Ubushushu be-gesig kubhekisa kwiqondo lobushushu apho izisombululo ze-HPMC zisenziwa khona iZiko leSigaba seSisombululo se-Gel.
Amanqanaba aphezulu okufaka endaweni kunye neemolekyuli zemolekyuli akhokelela kumaqondo obushushu asezantsi.
Ukuqonda ubushushu be-gesing kubalulekile ekuqulunqweni kweenkqubo zokuhambisa iziyobisi kunye nokuveliswa kweegels zezicelo eziphambili.

Iipropathi ze-Thermal:

Uzinzo lwe-thermal lubalulekile kwizicelo apho i-HPMC iphantsi kwe-HPMC ngexesha lokugcina okanye ukugcinwa.
I-DS HSMC inokwenza bonise uzinzo lwe-therm of thermal ngenxa yobukho beendlela ezigcina izinto ezinqabileyo.
Iindlela zohlalutyo lohlalutyo ezinjenge-calolorry eyahlukileyo (i-DSC) kunye nohlalutyo lwe-thermographimpric (i-TGA) isetyenziselwa ukuvavanya iipropathi ze-thermal.

Ukungasebenzi kunye nokudumba

Ukungasebenzi kunye nokudumba ngokuhamba kuxhomekeke kwi-DS, ubunzima bemolekyuli, kunye nobushushu.
I-DS ephezulu ye-DS kunye nemolekyuli yemolekyuli ebonakalayo ibonakalisa ukuntywila okukhulu nokudumba emanzini.
Ukuqonda ukonakala kunye nokudumba kuya kubaluleke kakhulu ekuyileni iinkqubo zokuhambisa iziyobisi kunye nokuqulunqa i-hydrogels kwizicelo zebhayimu.

IiPropathi zeRiology:

Iipropathi ze-Rheoology ezinje ngoVeksinity, i-Shear yokuziphatha, kwaye i-viscoelity ibalulekile kwizicelo ezahlukeneyo.
I-HPMCIzisombululo ezibonisa indlela yokuziphatha ye-pseudostic, apho i-viscosity inciphisa khona ngokukhulisa inqanaba le-Shear.
Iipropathi ze-RTMOC ze-HPMC iphembelele ukunyuka kwayo kumashishini anjengokutya, amayeza kunye namayeza.

Umahluko phakathi kweemodeli ezahlukeneyo ze-HPMC ukusuka kwisahluko kwimo yeekhemikhali, isidanga sokufaka, ubungakanani bemoya, i-gesing, iipropathi ze-thermal, i-sobing, impahla yokudumba, kunye neepropathi zengqolowa. Ukuqonda lo mahluko kubalulekile ekukhetheni ukwahluka okufanelekileyo kwe-HPMC ye-HPMC yezicelo ezithile, ukusukela ekuqulunqweni kwamayeza kwizixhobo zokwakha.