Hydroxypropyl methylcelculose (hpmc)

I-HydroxyPOpyl Methylcelceltulose (HPMC), ekwabizwa ngokuba yi-hypromellose, yi-polymer eguquguqukayo evela kwi-sellulose. Isetyenziswa ngokubanzi kumashishini ahlukeneyo kwipropathi yayo eyahlukileyo, kubandakanya amayeza, ukwakhiwa, ukutya, ukutya, i-cosmetics kunye nokhathalelo lomntu. Esi sikhokelo sibanzi, siza kuphonononga ubume bemichiza, iipropathi, inkqubo yokwenziwa, izicelo, kunye nezibonelelo ze-HPMC ngokweenkcukacha.

1. Intshayelelo kwi-HPMC:

I-HydroxyPOpyl Methylcelcelsulose (HPMC) yi-Ionic se-ionsulose ether ethathwe kwi-selupese yendalo ngokuguqulwa kweekhemikhali. Ihambelana nokuphatha i-seluplose nge-proplone oxide kunye ne-methyl chloride ukwazisa i-hydroxyl kunye namaqela e-methyl kwi-sellybone. I-polymer ebangela ibonisa uluhlu lweepropathi ezenza ukuba ibaluleke kakhulu kwizicelo ezahlukeneyo zeshishini.

I-2. Isakhiwo semichiza kunye neepropathi:

I-HPMC iphawulwa yindlela yayo yekhemikhali, equlethe i-selllose yeselfowuni kunye ne-hydroxypropy ye-hydroxyl kunye ne-methyl thata eqhotyoshelwe kumaqela e-hydroxyl. Inqanaba lokufakwa endaweni (DS) le-hydroxypropy kunye namaqela e-methyl inokwahluka, ikhokelela kumabakala ahlukeneyo e-HPMC enezinto ezahlukileyo ezinjengeempawu ezifana ne-viobing.

Iipropathi ze-HPMC ziphenjelelwa zizinto ezinje ngobunzima bemolekyuli, isidanga sokufaka endaweni, kunye ne-hydroxypropy / i-hethyl yomlinganiso. Ngokubanzi, i-HPMC ibonisa ezi ndawo ziphambili zilandelayo:

• I-Sol-Soliday
• Isakhono sokwenza ifilimu
• Ukutyibilika kunye nePropathi
• Umsebenzi womphezulu
• Uzinzo ngaphezulu kwe-pH ye-pH
• Ukuhambelana nezinye izinto

I-3. Inkqubo yokuvelisa:

Ukuveliswa kwe-HPMC kubandakanya amanyathelo aliqela, kubandakanya:

1. Ukulungiswa kwe-sellyulose: I-seluplose yendalo, ityalwe kwi-Pulp yeWood okanye umqhaphu, ihlanjululwe kwaye icociwe kwaye ihlaziywe ukususa ukungcola kunye ne-legsin.
2. I-Etheristition Reaction: I-Seleulose inyangwa nge-propylene oxide kunye ne-methyl chloride phambi kwe-alkali catalysts ukuyazisa i-hydroxylsts kunye namaqela e-methyl kwi-sellybone.
3. Ukungathathi cala kunye nokuhlamba: Imveliso yesiphumo ayithathi cala ukususa i-Alkali eyongezelelweyo kwaye emva koko ihlanjwe ukuze isuswe ziimveliso kunye nokungcola.
4. Ukomisa kunye nokugaya: I-HPMC ecocekileyo yomiswe kwaye iphantsi komgubo ococekileyo ofanelekileyo kwizicelo ezahlukeneyo.

4. Ibanga kunye neenkcukacha:

I-HPMC iyafumaneka kuluhlu lwamabakala kunye neenkcazo zokufezekisa iimfuno ezithile zamashishini ahlukeneyo kunye nokusetyenziswa. Oku kubandakanya ukwalelwa kwi-viscosity, ubungakanani bentsalela, inqanaba lokufaka endaweni, kunye nobushushu be-gesing. Amabakala aqhelekileyo e-HPMC abandakanya:

• Amabakala oLwimi oMiselweyo (umzekelo, i-4000 CPS, i-6000 CPS)
• Ibanga eliphezulu lemifanekiso (umz, i-15000 cps, 20000 cps)
• Amabakala e-Viscovity (umzekelo, i-CPS ye-1000, 2000 cps)
• Amabakala akhethekileyo kwizicelo ezithile (umzekelo, ukukhutshwa okuzinzileyo, ukukhutshwa okulawulwa)

5. Ukusetyenziswa kwe-HPMC:

I-HPMC ifumana ukusetyenziswa ngokubanzi kumashishini ahlukeneyo ngenxa yeepropathi zayo eziguquguqukayo kunye nokuhambelana kwezixhobo ezahlukeneyo. Ezinye zezinto eziphambili ze-HPMC zibandakanya:

a. Ishishini lamachiza:

• Ithebhulethi kunye ne-capsule coatings
• Ifomu elawulwa
• Iibhedi kunye neenkampani ezihlangeneyo kwiitafile
• Izisombululo ze-Ophthalmimic kunye nokunqunyanyiswa
• Iifomu eziPhambili ezinjengeekhrim kunye neoyile

b. Ishishini lokwakha:

• Iimveliso ezisekwe kwi-Gypsim kunye neGypsim (umzekelo, fert, iiplasters)
• Amachaphaza amdaka kunye ne-grict
• I-Exintsumpa yangaphandle kunye nokuGqibela iinkqubo (i-EIFS)
• Ukuzibandakanya
• Iipeyinti ezisekwe emanzini kunye neengubo

c. Ishishini lokutya:

• Ukutyibilika kunye nokuzinzisa iarhente kwiimveliso zokutya
• I-Emoulsifier kunye nokumisa iarhente kwiisosi kunye nokunxiba
• Izongezo zeFiber fiber
• Ukubhaka kwe-gluten-free kunye ne-confectionery

d. Inkathalo yobuqu kunye ne-cosmetics:

• I-thickener kunye nokumisa iarhente kwi-lotions kunye neekhrim
• I-Binder kunye nefilimu-ngaphambili kwiimveliso zokhathalelo lweenwele
• Ukukhululwa okulawulwayo kwifomu ye-skerCare
• Iliso lamehlo kunye nokunxibelelana lels Solutions

I-6. Izibonelelo zokusebenzisa i-HPMC:

Ukusetyenziswa kwe-HPMC kubonelela ngezibonelelo ezininzi kumashishini ahlukeneyo:

• Ukuphuculwa kweMveliso yeMveliso kunye nomgangatho
• Ukuqulunqwa kokuqhelisela ukuguqulwa kunye nokuzinza
• Ubomi oLwandisiweyo weshellofi kwaye buncitshisiwe
• Inkqubo ephuculweyo yokusebenza kunye nokusebenza ngendleko
• Ukuthobela iimfuno zomthetho kunye nemigangatho yokhuseleko
• Okuyisingqongileyo kunye ne-biompatid

7. Iindlela zexesha elizayo kunye nembono:

Imfuno ye-HPMC kulindeleke ukuba iqhubeke ukukhula, iqhutywa ngezinto ezinjengokukhula kwedolophu, uphuhliso lweziseko zophuhliso, kunye neemveliso zononophelo. Uphando oluqhubekayo kunye neenzame zophuhliso zijolise ekupheliseni iifomu ze-HPMC, ukwandisa izicelo zayo, kunye nokuphucula iinkqubo zokwenza imveliso ukuhlangabezana neemfuno zentengiso.

8. Ukuqukumbela:

I-HydroxyPOpyl Methylcelceltulose ye-Polymer eguquguqukayo ngezicelo ezahlukileyo kumashishini amaninzi amaninzi. Iipropathi zayo ezahlukileyo, ezinjengokungathobeli kwamanzi, ubuchule bokwenza ifilimu, kunye neepropathi ezinkulu, zenze luxabiseke kakhulu kwiindawo zamayeza, ukwakhiwa, ukwakhiwa, ukhathalelo lobuqu, kunye ne-cosmetics. Njengokuqhubela phambili kwetekhnoloji kunye neemfuno zentengiso, i-HPMC kulindeleke ukuba idlale indima ebaluleke ngakumbi ekwakheni ikamva lamashishini ahlukeneyo.