Iimfihlo zoShishino ze-Hydroxypropyl Methylcelcelgalose: Ungayikhetha njani ngokuchanekileyo?

Hydroxypropyl methylcelculose (hpmc), njengezinto ezibalulekileyo zekhemikhali, zisetyenziswa ngokubanzi kumasimi amaninzi anjengezokwakha, amayeza, ukutya kunye ne-cosmetics. Ukugcinwa kwayo okugqibeleleyo, ukugcinwa kwamanzi, ukwenza ifilimu kunye nokuzinzisa iipropathi kwenza ukuba ibe yinto ebalulekileyo yokuncedisa kumashishini amaninzi. Nangona kunjalo, ujongene noludwe lweemveliso ze-Inincel®HPMC kwimarike, indlela yokukhetha ngokuchanekileyo iimveliso ezilungele iimfuno zabo ziba ngumcimbi ophambili kwinkxalabo ezininzi kunye nabasebenzisi.

1. Qonda iimfuno ezizodwa zebala lesicelo

Iindawo ezahlukileyo zesicelo zineemfuno ezahlukeneyo zomsebenzi we-HPMC, kwaye imveliso efanelekileyo kufuneka yenziwe ngokwezifiso ngokweemfuno ezithile xa ukhetha. Oku kulandelayo ziimfuno zesicelo eziqhelekileyo:

Ishishini lokwakha: I-HPMC isetyenziswa ikakhulu kwi-podty powder, udaka oluxubileyo kunye nethayile, igxininisa ekugcinweni kwamanzi, iipropathi zokwakha nezakhiwa. Umzekelo, i-HPMC enendawo ephezulu yokugcina amanzi ingaphucula amandla okomisa okanye ukufakelwa ngelixa kunciphisa umngcipheko wokuqhekeka nokuwa.

Ishishini lamachiza amayeza: I-HRMACEOCATION-IBAKALA I-HPMC isetyenziselwa iirobhothi okanye iityhushu zecwecwe, ezineemfuno eziphezulu kakhulu zokucoceka kunye nokhuseleko, kwaye kufuneka zihambelane ne-USP kunye ne-EP.

Ishishini lokutya kunye ne-cosmetics njenge-tickener okanye i-stabilizer kufuneka ihlangane ukuqinisekiswa kwebakala lokutya (njengemigangatho ye-FDA) kunye neemfuno zetyhefu eziphantsi, kwaye kufanele ukuba kungazenzi ivumba.

2. Qonisa iparamitha yentsebenzo

Xa ukhetha i-HPMC, kufuneka ugxile kwezi paramitha zentsebenzo zilandelayo:

I-Viskosity: Viscosity yenye yezona zinto zibalulekileyo kwi-HPMC. I-VICMMC ephezulu ye-HPMC ifanelekile kwiimfuno eziphezulu zokutsala, ngelixa iimveliso ze-Viscofity eziphantsi zilungele izicelo ezineemfuno eziphakamileyo zobuqhophololo.

Isidanga sokufakwa endaweni (DS) kunye ne-molar I-HPMC enenqanaba eliphezulu lokufakelwa linomhlaba ongcono kunye nokunganyangeki kobushushu obuphezulu, kodwa iindleko zayo nazo ziphezulu.

Iimpawu zokuNikeza: I-HPMC yokwahlula-hlula i-HPMC isebenza ngakumbi ekwakhiweni nasekwuqhubekeni, kodwa kwezinye iimeko ezisilibaziseka, kodwa kwiimeko ezibambekayo, iimveliso eziguqulweyo eziguqulweyo kufuneka zikhethwe

3. Qonda ifuthe lezinto ezingafunekiyo kunye neenkqubo

Ukusebenza kwe-HPMC kunxulumene ngokusondeleyo nomthombo wezinto zayo ezibukhali kunye nenkqubo yemveliso:

I-selsulose iZinto eziPhakamileyo: I-Selupelose ephezulu yendalo sisiseko sokuvelisa ukusebenza okuphezulu kwe-HPMC ephezulu. I-seluplose engaphantsi inokubangela ukungazinzi kwemveliso okanye umxholo ongaphezulu kakhulu.

Inkqubo yemveliso: Inkqubo yemveliso ephambili inokuqinisekisa ukufana nokuzinza kwemveliso. Umzekelo, indlela yeSolvent yokulungiselela i-HPMC ingahlala ilawula ngcono ubunyulu kunye nokusasazwa kwemolekyuli yemveliso.

I-4. Nika ingqalelo kwisiqinisekiso esisemgangathweni kunye nokukhethwa komthengisi

Xa ukhetha umthengisi we-disnecpm®HPMC, ezi zinto zilandelayo kufuneka ziqwalaselwe:

Isiqinisekiso sokuqinisekiswa: Ukuqinisekisa ukuba imveliso idlulise isiqinisekiso senkqubo ye-ISO9001 yoLawulo lweSo900100 yoLawulo lwe-ISO90015 kunye neMigangatho yeShishini efanelekileyo (njenge-FDA, i-EU CE, njl. Njl.).

Inkxaso yezobugcisa: Abathengisi abakumgangatho ophezulu bahlala beneqela lezobuchwephesha kwaye banokubonelela ngezisombululo ezenziwe ngokwezifiso ngokweemfuno zabathengi.

Uzinzo lubonelela: Ukukhetha umvelisi omkhulu kwaye odumileyo anokuqinisekisa ukuhanjiswa kwezinto eziluhlaza kwaye uphephe ukuphazamiseka kwemveliso ezibangelwa kukunqongophala kwezinto eziluhlaza.

I-5. Ukuqonda okunzulu kwemizi-mveliso yeShishini kunye neendlela

Umzi-mveliso we-HPMC okwangoku unikezela ngale ndlela ilandelayo:

Ukukhusela okusingqongileyo kunye nokuluhlaza: Ukunyuka kokuqonda kokusingqongileyo, i-VOC ephantsi (i-Voc esezantsi) kunye neemveliso ze-HPMOC ezinokufumene ngakumbi.

Ukulungiswa kokuSebenza: Ngetekhnoloji yokuhlengahlengiswa kwekhemikhali, i-HPMC enemisebenzi ekhethekileyo njengokugcinwa kwamanzi, kunye nokugcinwa kwamanzi amanzi, kunye nokugcinwa kwamanzi asentloko kuphuhlisiwe ukubonelela ngokukhetha amashishini ahlukeneyo.

6. Kuphephe imigibe yoShishino

Kukho iimveliso eziphantsi kwe-HPMC kwimarike. Abasebenzisi kufuneka belumkele imigibe elandelayo xa kuthengwa:

Iiparamitha zelebheli: Abanye abavelisi banokuzigculela eziphambili ezinjenge-viscofity, kwaye eyona ntsebenzo ayinakufikelela kwixabiso elifanelekileyo.

Izithintelo zokuqulunqwa: Iindleko eziphantsi iAintlcel®HPMC zinokukrexezwa kwezinye iichemicals. Nangona ixabiso liphantsi, ifuthe lokusetyenziswa lincitshisiwe kakhulu, kwaye linokuchaphazela ukhuseleko lwemveliso.

Imfazwe yamaxabiso: Iimveliso ezinamaxabiso aphantsi kakhulu zihlala zithetha ukuba umgangatho kunzima ukuqinisekisa. Ukusebenza ngendleko kufuneka kuvavanywe ngokupheleleyo ngokudibeneyo kunye neemfuno zokwenyani.

Ukukhetha ilungelohydroxypropyl methylcelceluploseayisiyonto ilula. Ifuna ukuqwalaselwa ngokutsha kwezinto ezininzi ezinje ngeendawo zokwenza isicelo, iiparamitha zentsebenzo, umgangatho wezinto ezibonakalayo, kunye neziqinisekiso zabaxhasi. Kuphela kukuqonda okunzulu ishishini kwaye ukuphepha imigibe enokubakho unokufumana inzuzo kukhuphiswano lwentengiso oluvuthayo. Njengomsebenzisi, kuya kufuneka ugxile kwintsebenziswano yexesha elide kunye nenkxaso yezobugcisa, kwaye unike iziqinisekiso eziqinileyo zokusebenza kwemveliso kunye nophuhliso lwenkampani ngokukhetha ngokuchanekileyo i-HPMC.