Amagqabantshintshi nge-hydroxypropyl methylcelcelculose (hpmc)

Hydroxypropyl methylcelculose (hpmc)yi-supelose yeselluese ikhupha kunye ne-semi-symetic pollymer computer. Isetyenziswe ngokubanzi kumashishini amaninzi anjengokwakha, amayeza, ukutya, i-cosmetics kunye neengubo. Njenge-ionic selsulose ether, i-HPMC inomhlaba olungileyo, ifilimu eyenza ifilimu, i-adherion kunye nesenzo, kwaye ke sinexabiso elifanelekileyo lamasimi amaninzi.

1. Isakhiwo semichiza kunye neepropathi ze-HPMC

Isakhiwo se-molecular se-HPMC sithathwe kwi-sellyulose yendalo. Emva kokulungiswa kweekhemikhali, i-methyl (-och₃) kunye ne-hydroxypropyl (-och₂ch₂₂₂₂₂) amaqela aziswa kwikhonkco leselselose. Isakhiwo sayo esisiseko semichiza imi ngolu hlobo lulandelayo:

Imolekyuli yeselfowuni equlunqwe iyunithi ye-glucose exhunyiwe yi-β-1,4-Glycosidic Bonds;

I-methyl kunye ne-hydroxypropy yamaqela aziswa kwikhonkco leselselose ngokuphendula endaweni.

Esi sakhiwo sekhemikhali sinika i-HPMC le ndawo ilandelayo:

I-Solubaty yaManzi: Ngokulawula inqanaba lokufakwa endaweni ye-methyl kunye namaqela e-hydroxypropy, i-HPMC inokuhlengahlengisa isolula samanzi. Ngokubanzi, i-HPMC inokwenza isisombululo se-viscous kumanzi abandayo kwaye inesifo esihle samanzi.

Uhlengahlengiso lwe-VisCosity: UVenkile ye-HPMC unokuthi ulawulwa ngokuchanekileyo ngokuhlengahlengisa ubunzima bemolekyuli kunye nesidanga sokutshintsha iimfuno ezahlukeneyo zesicelo.

Ukuxhathisa ubushushu: kuba i-HPMC yimpahla ye-thermoplastic, ukumelana nobushushu bekulungile kwaye kunokugcina ukusebenza ngokuzinzileyo ngaphakathi koluhlu oluthile lobushushu.

I-biomicotible: I-HPMC yinto engenatyhefu kwaye engakhathaliyo, ngoko ke iqhutywa ikakhulu kwicandelo lezonyango.

2. Indlela yokulungiselela i-HPMC

Indlela yokulungiselela i-HPMC igqityiwe ikakhulu yindlela encaselweyo ye-selulose. Amanyathelo athile alandelayo:

Ukupheliswa kwe-seluplose: qala, xuba i-sellyulose yendalo ngesinyibilikisi (njenge-chloroform, isonjululo lotywala, njlnjl.) Ukusinyibilikisa isisombululo seselselose.

Utshintsho lweekhemikhali: I-Methyl kunye ne-HydroxyPLL yekhemikhali (efana ne-chloromethyl complets kunye ne-allyl yongezwe) yongezwa kwisisombululo sokusabela.

Ukungathathi cala kunye nokomisa: Ixabiso le-pH lihlengahlengiswa ngokwenza i-acid okanye i-alkali, kunye nokwahlula, ukucocwa kunye nokumisa kwenziwa emva kokuphendula kwe-hydylcelose.

3. Ukusetyenziswa kwe-HPMC

Ipropathi eyahlukileyo ye-HPMC yenza ukuba isetyenziswe ngokubanzi kwiindawo ezininzi. Oku kulandelayo zezinye zeendawo eziphambili:

. Ingaphucula ulwelo, ukunamathela kunye nokugcinwa kwamanzi komxube. Ingakumbi kudaka owomileyo, i-HPMC inokuphucula ukusebenza koludaka, yandisa ukunamathela kodaka, kwaye kuphephe ukugcuma kwisamente nge-cerry ngexesha lenkqubo yokuqhutywa.

(2) Intsimi yamayeza: Kwintsimi yamayeza, i-HPMC ihlala isetyenziselwa ukulungisa amacwecwe, i-capsules kunye neziyobisi ezingamanzi. Njengearhente yefilimu esenza ifilimu, i-thickener kunye ne-stabilizer, inokuphucula ukunyibilikisa kunye nokungafumaneki kweziyobisi. Kwiitafile, i-HPMC ayinakulawula kuphela inqanaba lokukhutshwa kweziyobisi, kodwa liphucula ukwanda kwamachiza.

. Umzekelo, ukutya okunamafutha aphantsi kunye namafutha, i-HPMC inokubonelela ngokuncamathela okungcono kunye nokuthungwa kunye nokwandisa uzinzo lwemveliso. Ikwasetyenziswa ngokubanzi ngokutya okubandayo ukuthintela ukwahlulwa kwamanzi okanye ukuqulunqwa kwekhristali.

. Ingaphucula ukuqulunqwa kwe-cosmetics, ibenze lula ukuba ifake isicelo kwaye ithathe. Ngakumbi kwizikhrimu zesikhumba, ii-shampoos, imaski yobuso kunye nezinye iimveliso, ukusetyenziswa kwe-HPMC kunokuphucula iimvakalelo kunye nokuzinza kwemveliso.

. Inokuphucula ukumelana kwamanzi kunye nokuchasana nokunxaxhila kokuthuka, kwaye kwandise ubulukhuni kunye nokunamathela.

I-4. Ithemba lentengiso kunye neendlela zoPhuculo lwe-HPMC

Njengoko abantu behlawula ngakumbi ukhuseleko lwendalo esingqongileyo, i-HPMC, njengezinto eziluhlaza nezingenabungozi, zinamathemba abanzi. Ingakumbi kumayeza, ukutya kunye nemizi-mveliso ye-cosmetics, ukusetyenziswa kwe-HPMC kuya kwandiswa ngakumbi. Kwixa elizayo, inkqubo yemveliso ye-HPMC inokwenzeka ukuba ilungiswe ngakumbi, kwaye ukwanda kokuphuma kunye nokuncitshiswa kweendleko kuya kukhuthaza ukusetyenziswa kwayo kumashishini amaninzi.

Ngokuphuhliswa kwezinto ezingenamsebenzi kunye netekhnoloji yokukhutshwa kwe-Smastration, ukusetyenziswa kwe-HPMC kwiinkqubo zokuhanjiswa kweziyobisi ze-smart ziya kuba yi-hotspot yophando. Umzekelo, i-HPMC inokusetyenziselwa ukulungiselela abathwali ngamachiza ngomsebenzi wokukhululwa olawulwayo ukuze basebenzise ixesha leziphumo zeziyobisi kwaye baphucule ukusebenza kakuhle.

Hydroxypropyl methylcelceluploseyinto ye-polymer ngentsebenzo ebalaseleyo kunye nesicelo ngokubanzi. Ngomoya obalaseleyo wamanzi, amandla okulungisa uVeksisity kunye ne-bimomatisi elungileyo, i-HPMC ibalulekile kwimimandla emininzi efana nokwakha i-HPMC inokuqhubeka nokwandisa, kwaye amathuba ophuhliso lwexesha elizayo anokuqhubeka nokwandisa kakhulu.