IBanga loShishino lwe-HPMC

IBanga loShishino lwe-HPMC

ibakala Pharmaceutical HPMCIHydroxypropyl methylcellulose imhlophe okanye ibisi emhlophe, ayinavumba, ayinancasa, ifayibha okanye igranule, ukwehla kobunzima xa isomiswa akudluli kwi-10%, inyibilika kumanzi abandayo kodwa hayi amanzi ashushu, kancinci emanzini ashushu Ukudumba, ukudumba, kunye nokwenza isisombululo se-viscous colloidal. , eba sisisombululo xa ipholile, kwaye ibe yijeli xa ishushu. I-HPMC ayinyibiliki kwi-ethanol, i-chloroform kunye ne-ether. Inyibilika kwi-solvent edibeneyo ye-methanol kunye ne-methyl chloride. Ikwanyibilika kwisinyibilikisi esixubeneyo se-acetone, i-methyl chloride kunye ne-isopropanol kunye nezinye izinyibilikisi eziphilayo. Isisombululo saso samanzi sinokunyamezela ityuwa (isisombululo sayo se-colloidal asitshabalaliswa yityuwa), kwaye i-pH ye-1% yesisombululo samanzi ngu-6-8. I-molecular formula ye-HPMC yi-C8H15O8-( C10H18O6) -C815O, kwaye ubunzima be-molecular mass malunga ne-86,000.

 

Ukucaciswa kwemichiza

Pi-HPMC enobungozi

Inkcazo

HPMC60E( 2910) HPMC65F( 2906) HPMC75K( 2208)
Ubushushu beGel (℃) 58-64 62-68 70-90
I-Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
IHydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity(cps, 2% Solution) 3, 5, 6, 15, 50,100, 400,4000, 10000, 40000, 60000,100000,150000,200000

 

Ibanga leMveliso:

Pi-HPMC enobungozi

Inkcazo

HPMC60E( 2910) HPMC65F( 2906) HPMC75K( 2208)
Ubushushu beGel (℃) 58-64 62-68 70-90
I-Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
IHydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity(cps, 2% Solution) 3, 5, 6, 15, 50,100, 400,4000, 10000, 40000, 60000,100000,150000,200000

 

 

Isicelo

PharmaAbancedisiIsicelo Pingoziceutical Gjonga i-HPMC Umthamo
Unyibiliko lweLaxative 75K4000,75K100000 3-30%
Iikhremu, iiGel 60E4000,75K4000 1-5%
Ukulungiswa kwamehlo 60E4000 01.-0.5%
Amalungiselelo amathontsi eliso 60E4000 0.1-0.5%
I-arhente yokunqumamisa 60E4000, 75K4000 1-2%
Ii-antacids 60E4000, 75K4000 1-2%
Iitafile zeBinder 60E5, 60E15 0.5-5%
Indibano eManzi iGranulation 60E5, 60E15 2-6%
Iingubo zeCwecwe 60E5, 60E15 0.5-5%
Ukukhutshwa okuLawulwayo kweMatrix 75K100000,75K15000 20-55%

 

 

Iimpawu kunye neeNzuzo:

I-HPMC inonyibiliko olubalaseleyo lwamanzi kumanzi abandayo. Iyakwazi ukuchithwa kwisisombululo esicacileyo kunye nokuvuselela okuncinci emanzini abandayo. Ngokuchasene noko, ayinyibiliki kumanzi ashushu angaphezu kwama-60kwaye inokudumba kuphela. Yi-ether ye-cellulose engeyiyo ionic. Isisombululo saso asinayo i-ionic intlawulo, ayifuni ukusebenzisana neetyuwa zetsimbi okanye i-ionic organic compounds, kwaye ayihambisani nezinye izinto eziluhlaza ngexesha lenkqubo yokulungiselela; inoburhalarhume obunamandla, kwaye njengoko iqondo lokutshintshwa kwisakhiwo se-molecular sanda, lichasene kakhulu ne-allergies kwaye lizinzile; ikwayi-inert ye-metabolically. Njengomxhasi wamachiza, ayenzi i-metabolized okanye ifunnwe. Ngoko ke, ayinikezeli ukushisa kumayeza kunye nokutya. Inekhalori esezantsi, ayinatyiwa, kwaye ayinatyiwa kubantu abanesifo seswekile. Iziyobisi ze-Allergenic kunye nokutya zinokusetyenziswa okukodwa; lizinzile kwi-acids kunye ne-alkali, kodwa ukuba ixabiso le-PH lidlula i-2 ~ 11 kwaye lichaphazelekayo ngamaqondo okushisa aphezulu okanye linexesha elide lokugcina, i-viscosity yayo iya kuncipha; isisombululo sayo samanzi sinokubonelela ngomsebenzi we-Surface, ebonisa ukunyanzeliswa komphezulu ophakathi kunye namaxabiso oxinzelelo lwangaphakathi; ine-emulsification esebenzayo kwiinkqubo zesigaba sesibini, ingasetyenziselwa njenge-stabilizer esebenzayo kunye ne-colloid ekhuselayo; isisombululo sayo samanzi sineempawu ezibalaseleyo zokwenza ifilimu, kwaye ithebhulethi kunye nepilisi Isixhobo esihle sokugquma. Ukufakwa kwefilimu eyenziwe yiyo kunenzuzo yokungabi mbala kunye nokuqina. Ukongeza i-glycerin kunokuphucula iplastiki yayo.

 

Ukupakishwa

Tukupakisha kwakhe umgangatho yi-25kg /Ifayibhaigubu 

20'I-FCL: iitoni ezili-9 ezinepalletized; Iitoni ezili-10 ezingafakwanga iipaleti.

40'FCL:18itoni ene-palletized;20itoni engafakwanga kwiipaleti.

 

Ugcino:

Yigcine kwindawo epholileyo, eyomileyo engaphantsi kwe-30 ° C kwaye ikhuselwe kumswakama kunye nokucinezela, ekubeni impahla i-thermoplastic, ixesha lokugcina akufanele lidlule kwiinyanga ezingama-36.

Amanqaku okhuseleko:

Le datha ingentla ihambelana nolwazi lwethu, kodwa musa ukukhulula abathengi ngokuyijonga ngononophelo yonke ngokukhawuleza xa uyifumene. Ukunqanda ukwakheka okwahlukileyo kunye nemathiriyeli ekrwada eyahlukeneyo, nceda wenze uvavanyo olungakumbi phambi kokuba uyisebenzise.

 


Ixesha lokuposa: Jan-01-2024