Ukuthatha amanyathelo okhuseleko xa inyibilika i-hydroxypropyl methylcelcelce

I-HydroxyPOpyl Methylcelceluplose Methylceltulose Methylceluplose Methylceluplose Methylceltulose Methylceluplose Methylceluplose Methylcelose, ekwandiwa njenge-HPMC, yi-Polymer, i-polymer ye-peliturmer enoluhlu olubanzi lwezicelo kumashishini kubandakanya nolwakhiwo, amayeza kunye nokutya. I-HPMC sisisele i-seluplose, oko kuthetha ukuba isuselwa kwi-sellulose, i-polymer yendalo efumaneka kwizityalo. Yeyona nto ixhaphakileyo i-ether sether ye-ether ngenxa yepropathi yayo eyahlukileyo kunye neendleko eziphantsi.

Ukuphelisa i-HPMC kunokuba yinkqubo yeqhinga, ngakumbi xa uzama ukufumana isisombululo se-homogeneous nesingaguqukiyo. Kweli nqaku, siza kuthetha ngezinto ezithile ezibalulekileyo ekufuneka ziqwalaselwe xa inyibilikisa i-HPMC ekuqinisekiseni ukupheliswa okuphumelelayo kunye neziphumo ezinqwenelekayo.

I-1.Intenter ye-HPMC

Ubunyulu be-HPMC bunokuchaphazela kakhulu ukulingana kwawo emanzini kunye nezinye izinyibilikisi. Ke ngoko, kubalulekile ukuqinisekisa ukuba i-HPMC esetyenzisiweyo iphakathi kunye nobunyulu. I-HPMC ingcoliswe kunye nezinye izinto zinokunganyibiliki kakuhle, zikhokelela kwiingxowa okanye iziqhushumbisi kwisisombululo. Oku kunokuchaphazela ukusebenza kweemveliso ezine-HPMC kwaye kunokubangela iingxaki ngexesha lenkqubo yokwenziwa.

I-2. Inombolo ye-HPMC ye-HPMC

I-HPMC iyafumaneka kumabakala ahlukeneyo kunye namanqanaba obuxoki, kwibakala ngalinye leyilelwe isicelo esithile. Ibakala le-HPMC elisetyenzisiweyo liya kumisela inani le-HPMC efunekayo kunye neqondo lokuhlaselwa. Kuxhomekeka kwibakala le-HPMC, iqondo lokuhlaselwa kunye nexesha liya kwahluka. Ke ngoko, kubalulekile ukuba ufundele ngononophelo kwaye ulandele imiyalelo yomenzi malunga nenani le-HPMC ukuze isebenzise kunye neqondo lobushushu elifunekayo lokuchithwa okusebenzayo.

I-3. I-Solvent kunye neqondo lobushushu

Ukukhetha i-SOLLPvey esetyenzisiweyo kunye neqondo lokuhlaselwa kwe-HPMC ye-HPMC yeyona nto iphambili kwimiba echaphazela inkqubo yokuphelisa. Amanzi yeyona isoyile isetyenziswa kakhulu kwi-HPMC, kwaye kubalulekile ukuqinisekisa ukuba amanzi asetyenzisiweyo aphezulu kwaye akanamdla. Amanzi acocekileyo anokubantselela enokuchaphazela ukubenzela i-HPMC ye-HPMC kunye nomgangatho wemveliso iyonke.

Iqondo lokushisa apho i-HPMC inyibilikisa khona nendima ebalulekileyo. I-HPMC iyanyibilika kakhulu emanzini afudumeleyo, ngokukhethekileyo phakathi kwe-80-90 ye-degrees celsius. Nangona kunjalo, kufuneka kuqatshelwe ukuba iqondo lobushushu alifanele liphakame kakhulu, kungenjalo i-HPMC iya kudityaniswa kwaye ihlazekile, ibekwe kukuncipha kwe-viscofity kunye nokusebenza kakubi. Ke ngoko, kubalulekile ukuba ulawule ngenyameko iqondo lobushushu lesinyibilikisi ukuqinisekisa ukusebenza okungaguqukiyo kunye nokuziphatha kakuhle.

4. Xuba kwaye uvuse

Ukuxuba kunye nokuphazamiseka kubalulekile ukuqinisekisa ukutshitshiswa okufanelekileyo kwe-HPMC. Ukudityaniswa ngokucokisekileyo kunye nokuphazamiseka kuya kunceda ukwehlisa amasuntswana e-HPMC kwaye wenze isisombululo se-homogeneneous nesingaguqukiyo. Ke ngoko, kubalulekile ukusebenzisa iindlela ezifanelekileyo zokudibanisa, ezifana nabaxube eziphakamileyo, ezincedayo ukunyusa amandla okuxuba amandla kunye nesiphithiphithi kwisisombululo.

I-5. Ukugxininiswa kwesisombululo se-HPMC

Uxinzelelo lwe-HPMC kwisisombululo yinto ebalulekileyo ekufuneka uyiqwalasele xa inyibilika i-HPMC. Ukuba uxinzelelo lwe-HPMC luphakame kakhulu, lunokubangela ukuqhwanyaza okanye i-agegramera ukuba yenze isisombululo, esenza kube nzima ukufumana isisombululo esifanayo. Kwelinye icala, ukuba uxinzelelo lusezantsi kakhulu, lunokubangela isisombululo esinxilisayo kwaye sisebenza kakubi.

ukuququmbela

I-HPMC yi-polymer eguquguqukayo kwaye iguquguqukayo ngoluhlu olubanzi lwezicelo kumashishini anjengokwakha, amayeza kunye nokutya. Ukupheliswa kwe-HPMC kunokuba yinkqubo yeqhinga, kwaye kubalulekile ukuba uqwalasele izinto ezinjengococeko, iBanga, i-Solvent, ukuxuba, kunye nokuSebenza kwesisombululo se-HPMC. Ukupheliswa okuphumelelayo kunye neziphumo ezinqwenelekayo kunokufezekiswa ngokulandela imiyalelo yomenzi kunye nokulawula ngononophelo ezi zinto.