1. Isiseko esisisiseko se-HPMC
I-HPMC (Hydroxypropyl methylcelcelcelsulose)sisixhobo se-polymer ye-polymer ethathwe kwi-seluplose yendalo. Iveliswa ikakhulu ngokutshintsha kwekhemikhali yeselfowuni kwaye isetyenziswa ngokubanzi kumayeza, ukutya, i-cosmetics nolwakhiwo. Kuba i-HPMC inyibilikiswa yamanzi, engenatyhefu, engenabungozi kwaye ingakhathali, ibe sisithako esiphambili kwiimveliso ezininzi.
Kumzi-mveliso wamayeza, i-HPMC ihlala isetyenziselwa ukulungiselela ukukhululwa kwamachiza amachiza, amaqokobhe e-capsule, kunye nokuzinzisa iziyobisi. Kukwasetyenziswa ngokubanzi kukutya njenge-thicker, i-enulsifier, i-Hulsifier kunye neStabilizer, kwaye isetyenziswa njengesithanga esisecalori esiphantsi kwizidlo ezithile ezikhethekileyo. Ukongeza, i-HPMC ikwasetyenziswa njenge-thi choner kunye ne-therinting isithako kwi-cosmetics.
2. Umthombo kunye nokuqulunqwa kwe-HPMC
I-HPMC sisisele i-etelulose ether efunyenwe ngokutshintsha kweekhemikhali kweselutase yendalo. I-Seleculose uqobo ingumtyholo obekiweyo kwizityalo, ezibandakanya icandelo elibalulekileyo leendonga zeseli zezityalo. Xa iqokelele i-HPMC, eyahlukeneyo eyahlukeneyo (enjenge-hydroxypropy ye-hydroxyl kunye ne-methyl) ziyaziswa ukuphucula ukwaphucula amandla ayo kunye neepropathi ezinkulu. Ke ngoko, umthombo we-HPMC yizinto zendalo zezityalo eziluhlaza, kunye nenkqubo yazo yokuguqulwa yenza ukuba inyibilike kwaye iguqulwe.
3. Ukusetyenziswa kwe-HPMC kunye nokunxibelelana nomzimba womntu
Intsimi yezonyango:
Kumzi-mveliso wamayeza, ukusetyenziswa kwe-HPMC kuboniswa ikakhulu kumalungiselelo okukhululwa ngamachiza. Kuba i-HPMC inokwenza ungqimba lwegel kwaye ilawule ngokufanelekileyo inqanaba lokukhutshwa kwechiza, lisetyenziswa ngokubanzi kuphuhliso lokukhululwa okuzinzileyo kunye namachiza alawulwayo. Ukongeza, i-HPMC ikwasetyenziswa njengeqokobhe le-capsule yamachiza, ngakumbi kwiicapsules zesityalo (iicapsules), apho inokutshintsha khona i-gelatini yesilwanyana kwaye ibonelele ngohlobo olunobuhlobo lwegesi.
Ukusuka kwimbonosela yokhuseleko, i-HPMC ithathwa njengekhuselekileyo njengesithako seziyobisi kwaye ngokubanzi ine-biomatisi elungileyo. Kuba ayinabungozi kwaye ayinabuntu emzimbeni womzimba, i-FDA (i-US yokutya kunye nolawulo lweziyobisi) ivumile i-HPMC njengendawo yokutya kunye neziyobisi ezibangelwa kukusetyenziswa kwexesha elide kufumaneka.
Ishishini lokutya:
I-HPMC isetyenziswa ngokubanzi kwishishini lokutya, ikakhulu njenge-gickener, i-sticker, i-emulsifier, njl. Isetyenziswe ngokubanzi ekutyeni, i-golts, iimveliso zobisi, ukutya kobisi kunye nezinye iimveliso. I-HPMC ikwasetyenziswa kwakhona kwimveliso ye-calorie ephantsi okanye iimveliso eziphantsi zefutha ngenxa yepropathi yayo enyibilikayo, ephucula incasa kunye nokuma.
I-HPMC ekutyeni ifunyanwa ngokutshintsha kweekhemikhali kweselfowuni yesityalo, kwaye uxinzelelo lwayo kunye nokusetyenziswa kwazo kulawulwa ngokungqongqo phantsi kwemigangatho yokusetyenziswa kwezibalo zokutya. Ngokwenzululwazi yangoku yesayensi kunye nemigangatho yokhuseleko lokutya yamazwe awahlukeneyo, i-HPMC ithathwa njengekhuselekile emzimbeni womntu kwaye ayinayo impendulo engaphambili okanye umngcipheko wezempilo.
Ishishini le-cosmetics:
Kwi-cosmetics, i-HPMC ihlala isetyenziswa njenge-thickener, i-mulsifier kunye nesithako esinyibilikisayo. Isetyenziswe ngokubanzi kwiimveliso ezinjengeekhrim, iingcibi zobuso, iikhrim zemehlo, imilebe, njl. Njl. Kuba i-HPMC inobulali kwaye ayicaphukisi ulusu, ithathwa njengesithako esifanelekileyo kuzo zonke iintlobo zolusu, ngakumbi ulusu olunobuthathaka.
I-HPMC ikwasetyenziswa kwi-ostints kunye nemveliso yolusu ukunceda ukuphucula uzinzo kunye nokungena kwezithako zamachiza.
I-4. Ukukhuseleka kwe-HPMC emzimbeni womntu
Uvavanyo lwetyhefu:
Ngokutsho kophando lwangoku, i-HPMC ithathwa njengekhuselekile emzimbeni womntu. Umbutho wezeMpilo weHlabathi (i-WHO), uMbutho wokutya nezoLimo Uluhlu lwe-FDA njenge-HPMC njenge "ishwankathelwa njengezinto ezikhuselekileyo" (GRAs) kwaye ivumela ukuba isetyenziswe njengendawo yokutya kunye neziyobisi.
UPhando lweKlinikhi kunye noHlahlelo lweMeko:
Izifundo ezininzi zeklinikhi zibonisile okoI-HPMCayibangeli naziphi na izinto ezigwenxa okanye iziphumo ebezingalindelekanga ngaphakathi koluhlu oluqhelekileyo. Umzekelo, xa i-HPMC isetyenziswa kumalungiselelo amachiza, abaguli bahlala bengabonisi ukuphendula okungahambelaniyo okanye olunye ungonwabi. Ukongeza, akukho zingxaki zempilo ezibangelwa kukusetyenziswa kakhulu kwe-HPMC ekutyeni. I-HPMC ikwathathelwa ingqalelo kukhuselekile kwezinye izinto ezikhethekileyo ngaphandle kokuba kukho into engekhoyo kwizithako zayo.
Impembelelo ye-allergic kunye nokuphendula okuchaseneyo:
Nangona i-HPMC ayihlali ibangela ukungasebenzi kakuhle, inani elincinci labantu abanovelwano kakhulu banokuba nakuphi na ukubandakanyeka kuyo. Iimpawu zokuphendula ngokungalingani zinokubandakanya ukubomvu kolusu, ukubetha, kunye nobunzima bokuphefumla, kodwa iimeko ezinjalo zinqabile kakhulu. Ukuba ukusetyenziswa kweemveliso ze-HPMC kubangela nayiphi na into engalunganga, yeka ukuyisebenzisa ngokukhawuleza kwaye unxibelelane nodokotela.
Iziphumo zokusetyenziswa kwexesha elide:
Ukusetyenziswa kwexesha elide kwe-HPMC akuyi kubangela nayiphi na imiphumo emibi emzimbeni womntu. Ngokutsho kophando lwangoku, akukho bungqina bokuba i-HPMC iya kubangela ukonakala kumalungu anjengesibindi kunye nezintso, kwaye ayiyi kuchaphazela amajoni omzimba. Ke ngoko, ukusetyenziswa kwexesha elide kwe-HPMC khuselekile phantsi kokutya okhoyo kunye nemigangatho yamayeza.
5. Ukuqukumbela
Njengesixhobo esivela kwi-sellulose yendalo, i-HPMC isetyenziswa ngokubanzi kumasimi amaninzi anje ngamayeza, ukutya kunye ne-cosmetics. Inani elikhulu lezifundo zesayensi kunye neemvavanyo zetyhefu zibonise ukuba i-HPMC ikhuselekile kuluhlu olusengqiqweni kwaye alunatywina olunobungozi okanye i-pathogenic emzimbeni womntu. Nokuba ngamalungiselelo e-chikeceutical, iisayizi zokutya okanye i-cosmetics, i-HPMC ithathwa njengesithako esikhuselekileyo nesisebenzayo. Ewe kunjalo, ukuze kusetyenziswe nayiphi na imveliso, imigaqo efanelekileyo yokusetyenziswa kufuneka ilandelwe, ukusetyenziswa kakhulu kufuneka kuthintelwe, kwaye kuthathelwa ingqalelo kufuneka kuhlawulwe kwimeko yokusetyenziswa kwe-allergic ngexesha lokusetyenziswa. Ukuba unengxaki zempilo ezizodwa okanye iinkxalabo, kuyacetyiswa ukuba unikezele ngogqirha okanye ubungcali.
Ixesha leposi: NgoDE-11 ukuya ku-1124