1. Ushwankathelo lwe-HPMC
I-HPMC (Hydroxypropyl methylcelcelcelsulose) sisifo se-selsulose efunyenwe ngokutshintsha kwamachiza. Ifunyanwa kwiseti yendalo ngokwemichiza yokuphendula kweekhemikhali ezinje nge-methysity kunye ne-hydroxyduproupy. I-HPMC inomoya ofanelekileyo wamanzi, uhlengahlengiso lwe-viscosity, iiprofayili zokwenza ifilimu kunye nozinzo, ngoko ke zisetyenziswe kumacandelo okutya, i-cosmetics, i-stictotic, i-gilsifier kunye nearhente yeGeul.
Kwishishini lokutya, i-HPMC ihlala isetyenziswa njenge-thianer, iarhente yegicko, i-Hulsiment, i-Emulsifier kunye nokuzinzisa. Uluhlu lwayo lwesicelo lukhona Isizathu esibalulekileyo sesicelo sayo kukuba i-Nunt.hpMMC inozinzo oluhle, akukho lula ukusabela kwezinye izithako, kwaye icociwe ngokulula phantsi kweemeko ezifanelekileyo.
2. Uvavanyo loKhuseleko lwe-HPMC
I-HPMC ivunyiwe kwaye yamkelwe ziiarhente ezininzi zoKhuseleko kuZwelonke kunye noKhuseleko lweHlabathi njengendawo yokutya. Ukhuseleko lwabo luvavanywa ikakhulu ngale miba ilandelayo:
Isifundo seToolotyOlogy
Njengokukhutshwa kwe-sellyulose, i-HPMC isekwe kwi-seluplose yesityalo kwaye iphantsi kakhulu. Ngokwezifundo ezininzi zeToolotyOlogy, ukusetyenziswa kwe-HPMC ekutyeni akubonisi ityhefu ecacileyo okanye engapheliyo. Uninzi lwezifundo lubonise ukuba i-HPMC ineziphumo ezilungileyo kwaye aziyi kubangela impembelelo ebonakalayo emzimbeni womntu. Umzekelo, iziphumo zovavanyo lwetyhefu yetyhefu ye-HPMC kwi-MPMC iboniswe ukuba akukho kuphendula ityhefu kwi-Dous Doels (kudlula ukusetyenziswa kwemihla ngemihla).
Ukuthambisa kunye ne-adis (i-intshi eyamkelekileyo)
Ngokutsho kovavanyo lweengcali zokhuseleko lokutya, ukuthathwa kwemihla emnandi (i-ADI) ye-HPMC ayiyi kwenzakalisa impilo yabantu ngaphakathi kokusetyenziswa kwengqondo. IKomiti yeNgqondo yeHlabathi kwiizongezo zokutya (i-jecfa) kunye nolawulo lweziyobisi (i-FDA) kunye namanye amaziko aziqonda ukhuseleko lwe-HPMC njengemida yokutya kwaye ibeka imida efanelekileyo yokutya kwaye ihlawule imida efanelekileyo yokutya. Kwingxelo yayo yovavanyo, uJecfa achaze ukuba i-HPMC ayikhange ibonakalise nayiphi na impembelelo ebonakalayo, kwaye ukusetyenziswa kwayo kukutya ngokubanzi kulingezantsi kwexabiso le-ADI, ngenxa yoko abathengi akufuneki bakhathazeke ngemingcipheko yempilo.
Impembelelo ye-allergic kunye nokuphendula okuchaseneyo
Njengezinto zendalo, i-HPMC inesimo esisezantsi se-allergic. Uninzi lwabantu alunamsebenzi wokuphambuka kwe-HPMC. Nangona kunjalo, abanye abantu abanobuthathaka banokufumana iimpawu ezinobulali ezinobulali njengokungxama kunye nokuphefumla xa besitya ukutya okune-HPMC. Ukuphendula okunjalo kuhlala kunqabile. Ukuba ukungonwabi kwenzeka, kuyacetyiswa ukuyeka ukutya okune-HPMC kwaye ufune ingcebiso yogqirha oqeqeshiweyo.
Ukusetyenziswa kwexesha elide kunye nempilo yamathumbu
Njenge-sumplaund yemoraur ephezulu, i-Nqulcel®HPMC kunzima ukuba ingene emzimbeni womntu, kodwa inokudlala indima ethile njengefibre yefibutha kwithumburi kunye nokukhuthaza i-peristals ye-intestine. Ke ngoko, ukuthathwa kwe-HPMC kunokuba nefuthe elithile elifanelekileyo kwimpilo yamathumbu. Umzekelo, ezinye izifundo zibonise ukuba i-HPMC inokwenzeka ekuphuculeni i-peristals yamathumbu kunye nokukhulula ukuqiniswa. Nangona kunjalo, ukuthathwa okugqithisileyo kwe-HPMC kunokubangela ukungakhethi cala, ukuhlazeka kwesisu, isifo sohudo kunye nezinye iimpawu, ke ngoko umgaqo wokumodareyitha kufuneka ulandelwe.
3. Imeko yokuvunywa kwe-HPMC kumazwe ahlukeneyo
China
E China, i-HPMC idweliswe njengeyona nto ivunyelweyo yokutya, ikakhulu isetyenziswa kwiipipi, iimveliso, iimveliso zePasta, njl. " Ukutya okuthile kwaye kusebenzise umda wokusetyenziswa.
udibano lwaseyurophu
Kwi-European Union, i-HPMC ikwamkelwe njengento ekhuselekileyo yokutya, i-E464. NgokweNgxelo yoVavanyo lweGunya loKhuseleko loKutya eYurophu (i-EFSA), i-HPMC ikhuselekile phantsi kweemeko ezichaziweyo zokusetyenziswa kwaye ayibonisi iziphumo ezibi kwimpilo yabantu.
Amazwe Amanyene
Uluhlu lwe-US FDA njenge "ishwankathelwa njengezinto ezikhuselekileyo" (GRAs) kwaye ivumela ukusetyenziswa kwayo ekutyeni. I-FDA ayizibeki imida ye-dosings engqongqo yokusetyenziswa kwe-HPMC, kwaye ikakhulu ivavanya ukhuseleko lwayo ngokusekwe kwidatha yesayensi ekuqondeni.
Njengesongezo lokutya,I-HPMC ivunyiwe kumazwe amaninzi nakwimimandla ehlabathini kwihlabathi liphela kwaye ithathwa njengekhuselekile ngaphakathi kuluhlu oluchaziweyo. Ukhuseleko lwayo luqinisekisiwe ngezifundo zetyhefu ezininzi zetyhefu kunye neendlela zeklinikhi, kwaye ayibangeli ingozi enkulu kwimpilo yabantu. Nangona kunjalo, njengazo zonke iizongezo zokutya, ukuthathwa kwe-HPMC kufuneka kulandele umgaqo wokuzisebenzisa ngokufanelekileyo kwaye uphephe ukuthathwa okugqithisileyo. Abantu abaneempawu ze-allergies kufuneka balumke xa besitya ukutya okuqulatha i-HPMC ukunciphisa ukungabikho kokuphendula okuchaseneyo.
I-HPMC yintshatsheli esetyenziswa ngokubanzi nekhuselekileyo kumzi-mveliso wokutya, ibeka emngciphekweni omncinci kwimpilo yoluntu. Ngokuqhubela phambili kwesayensi kunye netekhnoloji, uphando kunye nokubekwa esweni kwe-IninCel®hpmc kunokuba yinto engakumbi kwixa elizayo ukuqinisekisa ukhuseleko lwayo.
Ixesha leposi: NgoDE-31 ukuya ku-2424