Ukhuseleko lwe-HPMC kwizongezo zokutya

1. Isishwankathelo se-HPMC

I-HPMC (Hydroxypropyl Methylcellulose) yi-cellulose derivative efunyenwe ngokuguqulwa kweekhemikhali. Ifumaneka kwi-cellulose yezityalo zendalo ngokusebenzisa iikhemikhali ezifana ne-methylation kunye ne-hydroxypropylation. I-HPMC ine-solubility efanelekileyo yamanzi, ukulungiswa kwe-viscosity, iipropati zokwenza ifilimu kunye nokuzinza, ngoko isetyenziswe ngokubanzi kumashishini amaninzi, ngakumbi kwiindawo zokutya, amayeza kunye nezithambiso, njenge-thickener, stabilizer, emulsifier kunye ne-gelling agent.

Kushishino lokutya, i-HPMC isoloko isetyenziswa njenge-thickener, i-agent ye-gelling, i-humectant, i-emulsifier kunye ne-stabilizer. Uluhlu lwesicelo sayo ekutyeni lubandakanya: isonka, iikeyiki, iibhiskithi, iilekese, i-ayisikrimu, iziqholo, iziselo kunye nokutya okunempilo. Isizathu esibalulekileyo sokusetyenziswa kwayo ngokubanzi kukuba i-AnxinCel®HPMC inozinzo oluhle lweekhemikhali, akulula ukusabela kunye nezinye izithako, kwaye iyancipha ngokulula phantsi kweemeko ezifanelekileyo.

2. Uvavanyo lokhuseleko lwe-HPMC

I-HPMC yamkelwe kwaye yamkelwa zii-arhente ezininzi zesizwe nezamazwe ngamazwe ezilawula ukhuseleko lokutya njengesongezo sokutya. Ukhuseleko lwayo luvavanywa ikakhulu ngale miba ilandelayo:

Uphononongo lweToxicology

Njengenye yezinto eziphuma kwi-cellulose, i-HPMC isekwe kwi-cellulose yezityalo kwaye inetyhefu esezantsi noko. Ngokwezifundo ze-toxicology ezininzi, ukusetyenziswa kwe-HPMC ekutyeni akubonisi ubutyhefu obucacileyo okanye obungapheliyo. Uninzi lwezifundo lubonise ukuba i-HPMC ine-biocompatibility elungileyo kwaye ayiyi kubangela iziphumo ezicacileyo eziyityhefu emzimbeni womntu. Umzekelo, iziphumo zovavanyo olubukhali lwetyhefu yomlomo lwe-HPMC kwiimpuku lubonise ukuba akukho mpendulo icacileyo yetyhefu eyenzekayo kwiidosi eziphezulu (ngaphezu kokusetyenziswa kwemihla ngemihla kwezongezo zokutya).

I-Intake kunye nee-ADIs (Ukuthathwa kwemihla ngemihla okwamkelekileyo)

Ngokovavanyo lweengcali zokhuseleko lokutya, ukuthathwa kwemihla ngemihla okwamkelekileyo (ADI) kwe-HPMC akusayi kulimaza impilo yabantu kuluhlu olufanelekileyo lokusetyenziswa. I-International Expert Committee on Food Additives (JECFA) kunye ne-US Food and Drug Administration (FDA) kunye namanye amaziko aye aqaphela ukhuseleko lwe-HPMC njengesongezo sokutya kunye nokubeka imida yokusetyenziswa efanelekileyo kuyo. Kwingxelo yayo yokuvavanya, i-JECFA ibonise ukuba i-HPMC ayizange ibonise nayiphi na imiphumo eyityhefu ecacileyo, kwaye ukusetyenziswa kwayo ekutyeni ngokubanzi kungaphantsi kwexabiso le-ADI elibekiweyo, ngoko ke abathengi akudingeki bakhathazeke malunga neengozi zayo zempilo.

Ukwaliwa kunye neempembelelo ezimbi

Njengento yendalo, i-HPMC inezehlo ezisezantsi ngokwentelekiso zokwaliwa. Uninzi lwabantu alunaziphumo zokwalana ne-HPMC. Nangona kunjalo, abanye abantu abanovelwano banokufumana iimpawu ezinobuthathaka ezinjengokuqhawuka kunye nokuphefumla kancinci xa besitya ukutya okune-HPMC. Ngokuqhelekileyo ukusabela okunjalo kunqabile. Ukuba kukho ukungakhululeki, kuyacetyiswa ukuba uyeke ukutya ukutya okuqulethe i-HPMC kwaye ufune iingcebiso zogqirha oqeqeshiweyo.

Ukusetyenziswa kwexesha elide kunye nempilo yamathumbu

Njenge-high-molecular compound, i-AnxinCel®HPMC inzima ukuba ifakwe ngumzimba womntu, kodwa inokudlala indima ethile njengefayibha yokutya emathunjini kwaye ikhuthaze i-intestinal peristalsis. Ke ngoko, ukuthatha okuphakathi kwe-HPMC kunokuba nefuthe elithile elihle kwimpilo yamathumbu. Ngokomzekelo, ezinye izifundo zibonise ukuba i-HPMC inamandla athile ekuphuculeni i-peristalsis yamathumbu kunye nokunciphisa ukuqhina. Nangona kunjalo, ukuthathwa ngokugqithisileyo kwe-HPMC kunokubangela ukungahambi kakuhle kwamathumbu, ukuphazamiseka kwesisu, isifo sohudo kunye nezinye iimpawu, ngoko ke umgaqo wokumodareyitha kufuneka ulandelwe.

3. Ubume bokuvunywa kwe-HPMC kumazwe ahlukeneyo

eTshayina

E-China, i-HPMC idweliswe njengezongezo zokutya ezivumelekileyo, ezisetyenziswa kakhulu kwiilekese, i-condiments, iziselo, iimveliso zepasta, njl. Ngokutsho kwe-"Standard for the Use of Food Additives" (GB 2760-2014), i-HPMC ivunyiwe ukuba isetyenziswe. ekutyeni okuthe ngqo kwaye inemida yokusetyenziswa engqongqo.

udibano lwaseyurophu

Kwi-European Union, i-HPMC ikwabonwa njengesongezo sokutya esikhuselekileyo, esinenombolo ye-E464. Ngokwengxelo yovavanyo ye-European Food Safety Authority (EFSA), i-HPMC ikhuselekile phantsi kweemeko ezichaziweyo zokusetyenziswa kwaye ayibonisi iziphumo ezibi kwimpilo yabantu.

Amazwe Amanyene

I-FDA yase-US idwelisa i-HPMC njengeyona nto “Eyaziwa Ngokubanzi njengeKhuselekileyo” (GRAS) kwaye ivumela ukusetyenziswa kwayo ekutyeni. I-FDA ayibeki imida yedosi engqongqo yokusetyenziswa kwe-HPMC, kwaye ikakhulu ivavanya ukhuseleko lwayo ngokusekelwe kwidatha yesayensi ekusetyenzisweni kokwenyani.

Njengesongezo sokutya,HPMC yamkelwe kumazwe amaninzi nakwimimandla kwihlabathi jikelele kwaye ithathwa njengekhuselekile phakathi koluhlu losetyenziso oluchaziweyo. Ukhuseleko lwayo luye lwaqinisekiswa zizifundo ezininzi ze-toxicological kunye nezenzo zeklinikhi, kwaye ayibangeli umonakalo omkhulu kwimpilo yabantu. Nangona kunjalo, njengazo zonke izongezo zokutya, ukuthathwa kwe-HPMC kufuneka kulandele umgaqo wokusetyenziswa okufanelekileyo kwaye uthintele ukutya kakhulu. Abantu abane-allergies kufuneka balumke xa besitya ukutya okuqulethe i-HPMC ukunciphisa ukwenzeka kokusabela okubi.

I-HPMC sisongezo esisetyenziswa ngokubanzi nesikhuselekileyo kushishino lokutya, ibeka umngcipheko omncinci kwimpilo yoluntu. Ngokuqhubela phambili kwesayensi kunye nobuchwepheshe, uphando kunye nolawulo lwe-AnxinCel®HPMC lunokuba nzima kwixesha elizayo ukuqinisekisa ukhuseleko lwayo.