Hydroxypropyl methylcelculose (hpmc)Ngaba i-polymer eguquguqukayo idla ngokusetyenziswa kuluhlu olubanzi lwezicelo, kubandakanya amayeza, iimveliso zokutya, izixhobo zokuthathwa, kunye nokusebenzisa imizi-mveliso. Umgangatho we-HPMC unokwahluka ngokuxhomekeka kwizinto ezifana nobunzima bemolekyuli, i-viscosity, isidanga sokufakwa endaweni, esinefuthe ngqo kwintsebenzo yayo kwizicelo ezithile.
Izinto eziphambili ezichaphazela umgangatho we-hydroxypropyl methylcelcelceluplose
Ubunzima bemolekyuli
Ubunzima bemolekyuli (i-MW) ibhekisa kubungakanani be-cantcel®hpmm ye-molecule kwaye idlala indima ebalulekileyo ekuqinisekiseni i-viscofity yayo kunye nokuluka. Ubunzima obuphezulu be-rolecular i-HPMC buhlala bube ne-viscofity ephezulu, esebenziseka kwizicelo ezinje ngokukhululwa kweziyobisi okanye njengearhente yokuthambisa kwiifom ezahlukeneyo.
Ubunzima obuphantsi kwemolekyuli (LMW): Ukutshintshwa okukhawulezileyo, uVenkile osezantsi, ngakumbi ngakumbi kwizicelo ezinjengeengubo kunye nokwenza ifilimu.
Ubunzima bemolekyuli ephezulu (hmw): Ukuchitheka kancinci, i-viscofity ephezulu, ilungele ukuqina, ukugcwala, kunye neenkqubo zokuthumela iziyobisi.
Inqanaba lokufakwa endaweni (DS)
Inqanaba lokufaka endaweni lubhekisa kwinqanaba lokuba amaqela e-hydroxyl kwi-selsulose overbne afakwa endaweni ye-methyl kunye namaqela e-hydroxypropyl. Le nto ichaphazela ukwahlukana kunye neepropathi zengqolowa yePolymer.
I-DS ephantsi: Ukunciphisa ukulinganisa amanzi, amandla aphezulu egesi.
I-DS ephezulu: Ukunyusa ukuzola kwamanzi, amandla ejeli encitshisiweyo, kunye nepropathi elawula ngcono kwi-PHMAHEMACECS.
I-viscofity
UVICWASITY yinto ebaluleke kakhulu ekuqinisekiseni ukuba i-HPMC inokwenza njani ukuthambisa, ukuzinzisa, kunye nezicelo zokugcwalisa. I-HPMPIty ye-HPMC isetyenziswa kwizicelo ezinjenge-emulsoon, ukunqunyanyiswa, kunye nee-hydrogels, ngelixa amabakala e-Viscosity elungele ukutya kunye neefomu zamayeza.
I-viscofity ephantsi: Ngokwesiqhelo isetyenziselwa ukutya, ukhathalelo lobuqu, kunye neefomu zamayeza zokwenza ifilimu kunye nokubopha.
I-viscofity ephezulu: Isetyenziswe kwifom yokukhutshwa kwamachiza, amandla amakhulu, kunye neebhuleki kwiimveliso zemizi-mveliso.
Ubunyulu
Inqanaba lokungcola, ezinjengezinto ezihlaselayo, iityuwa eziguqulweyo, kunye nezinye izinto ezingcolisayo, zinokuchaphazela kakhulu ukusebenza kwe-ganceplel®hpmc. Amabakala aphezulu ococeko aphezulu ahlala efunwa kwizicelo zamayeza kunye nokutya.
Ibakala lamayeza: Ukucoceka okuphezulu, kudla ngokuhamba kunye nolawulo lokuqina kwiintsalela kunye nokungcola.
Ibanga lezorhwebo: Ukucoceka okuphantsi, kwamkelekile kwizicelo ezingasetyenziswanga okanye ezingasetyenziswanga.
Ukunyibilikisa
Ukunyibilisela i-HPMC emanzini kuxhomekeke kubunzima bayo kunye nenqanaba lokufaka endaweni. Ngokwesiqhelo, i-HPMC inyibilikisa emanzini abandayo, isenza ukuba ibe lukhetho oluhle kakhulu lwezicelo ezifuna ukusetyenziswa kwamanzi.
Ukulinganisa okusezantsi: Ngaphantsi kwenziwe inyibiliki, isetyenziselwa iinkqubo zokukhutshwa kwemvume.
I-SORING EPRING: Inyibiliki ngakumbi, ilungele izicelo ezifuna ukutshitshiswa okukhulu.
Uzinzo lwe-thermal
Ukuzinza kwe-HPMC yinto ephambili, ngakumbi kumashishini ebandakanya ukuqhubekeka kubushushu obuphezulu. Uzinzo oluphezulu lwe-thermal lunokuba lubalulekile kwizicelo ezinjengeengubo zetafile nakwishishini lokutya.
Amandla eGel
Amandla ejel kubhekisele kubuchule be-HPMC ukwenza ijeli xa idityaniswa namanzi. Amandla aphezulu egel anqweneleka kwizicelo ezinje ngeenkqubo zokuhambisa iziyobisi, kunye namandla ejeli ephantsi zihlala zikhethwa kwizicelo ezinje ngeenkqubo zokunqunyulwa kunye nokuziswa.
Itheyibhile yokuthelekisa: Imicimbi esemgangathweni ye-hydroxypropyl methylcelcelcelceluplose
| Into | Umgangatho ophantsi we-HPMC | Umgangatho ophezulu we-HPMC | Impembelelo ekusebenzeni |
| Ubunzima bemolekyuli | Ubunzima obuphantsi kwemolekyuli (LMW) | Ubunzima obuphezulu bemolekyuli (hmw) | I-LMW inyibilikisi ngokukhawuleza, i-HMW ibonelela nge-viscofity ephezulu kunye ne-geser eqinileyo. |
| Inqanaba lokufakwa endaweni (DS) | I-DS ephantsi (incinci) | I-DS ephezulu (engaphezulu) | I-DS esezantsi inika amandla angcono ejele, i-DS ephezulu iphucula isomeleza. |
| I-viscofity | I-viscofity ephantsi, ukunyibilikisa ngokukhawuleza | I-viscofity ephezulu, ukuthambisa, ukwenza igesi | I-viscofity ephantsi ilungele ukusasazeka ngokulula, i-viscofity ephezulu yokuzinza kunye nokukhululwa okuzinzileyo. |
| Ubunyulu | Amanqanaba aphezulu okungcola (iityuwa ze-inorganic, izinyibilikisi) | Ukucoceka okuphezulu, ukungcola okungapheliyo | Ucoceko oluphezulu luqinisekisa ukhuseleko kunye nokusebenza kakuhle, ngakumbi kwiindawo zamayeza kunye nokutya. |
| Ukunyibilikisa | Ukugula kakubi kumanzi abandayo | I-solity elungileyo emanzini abandayo | I-solubility ephezulu iluncedo kwiingubo kunye nezicelo zokukhutshwa ngokukhawuleza. |
| Uzinzo lwe-thermal | Uhlala uzinzo lwe-thermal | Uzinzo oluphezulu lwe-thermal | Uzinzo oluphakamileyo lwe-thermal olukhethwa kwiindawo zobushushu obuphakamileyo. |
| Amandla eGel | Amandla e-gene ephantsi | Amandla amakhulu | Amandla aphezulu egel ayimfuneko ekukhutshweni okulawulwayo kunye neenkqubo zokugcwala. |
| Imbonakalo | I-tyheli okanye i-off-white-white, i-cully | Mhlophe ukuya kwi-Off-White-Sheet | I-HPMC ekumgangatho ophezulu ye-HPMC iya kuba nenkangeleko efanayo, ebonisa ukungqinelana kwimveliso. |
Ukuqwalaselwa okusekwe kusekwe kwisicelo
Ishishini lamachiza: Kumsebenzi wamayeza, ubunyulu, i-viscosity, ubunzima beemolekyuli, amandla egesi ziimpawu ezibalulekileyo ze-HPMC. Ukukhutshwa okulawulwayo kwamathafa asebenzayo
Ishishini lokutya: Kwiimveliso zokutya, ngakumbi kwizicelo ezinjengeereyithi zokutya, iiarhente zokuchonga, kunye ne-eulsifiers, i-HPMCSE ye-viscofity esezantsi kunye ne-Soling ngokulinganiselweyo zihlala zikhethwa. I-HPMP ekumgangatho ophezulu yokutya okuphezulu iqinisekisa ukhuseleko lwabathengi kwaye ihlangabezana nemigangatho yokusetyenziswa.
I-Cosmetic kunye nokhathalelo lomntu: Kwi-cosmetics, i-chancel®hl®hpmc isetyenziselwa ukwahlulwa, ukuqina, kunye nokwenza ifilimu. Apha, i-viscosity kunye nomoya ubalulekile ekudalani iindlela ezizinzileyo njengechibi, iikhrim, kunye neemveliso zeenwele.
Ukusetyenziswa kweMizi-mvelisoIzicelo zemizi-mveliso, ezinjengeepeyinti, amachaphaza, amanqaku e-HPMCIty ye-HPMC eziphezulu ze-HPMC zihlala zisetyenziselwa ukuqina kunye nokwenziwa kwefilimu. Ugxininiso kuzinzo lobushushu, ubunyulu, kunye nokuVala kubaluleke kakhulu ekuqinisekiseni intsebenzo yemveliso efanelekileyo kwiimeko ezinzima.
Umgangatho weHydroxypropyl methylcelceluploseinokuphembelela kakhulu intsebenzo yayo kuwo onke amashishini eyahlukeneyo. Ngokuqonda izinto ezifaka isandla kumgangatho wayo-njengokugula kwe-molecular, isidanga sokufakwa endaweni, ukugcinwa, ukucoceka, ukungazithembi, ukukhetha inqanaba elifanelekileyo. Nokuba ngaba usebenzise imveliso yokutya, ukuveliswa kokutya, okanye imveliso yokutya, ukuqinisekisa ukuba inqanaba elisezantsi le-HPMC likhethwe kuya kuphucula ukusebenza kunye nokusebenza kwemveliso yokugqibela.
IXESHA LOKUQALA: UJAN-27-2025