Ukungasebenzi kwe-HPMC

I-HydroxyPOpyl Methylcelceltulose (HPMC) inyibilikisiwe emanzini, yenye yezona ndawo zibalulekileyo kwaye inegalelo ekusebenziseni izicelo ezahlukeneyo. Xa uyongezwa kumanzi, i-HPMC isasaza kunye ne-hldrate, yenza izisombululo ezicacileyo nezicacileyo. Ukunyibilisela i-HPMC kuxhomekeke kwizinto ezininzi, kubandakanya inqanaba lokufakwa endaweni (DS), ubunzima bemoyara, kunye neqondo lobushushu lesisombululo.

Ngokubanzi, i-HPMC enexabiso eliphantsi le-DS lithanda ukuba linyibilike kakhulu emanzini xa kuthelekiswa ne-HPMC ngexabiso eliphezulu le-DS. Ngokufanayo, i-HPMC enenqanaba lemolekyuli elisezantsi inokuba namaxabiso ashiyekileyo afakelweyo xa kuthelekiswa namabanga aphezulu eemolekyuli.

Iqondo lobushushu lesisombululo likwaphembelela ukunyibilika kwe-HPMC. Amaqondo obushushu aphezulu aqala ukuphucula ulwahlulo lwe-HPMC, avumele ukutshitshiswa ngokukhawuleza kunye nokuchithwa kwe-hydration. Nangona kunjalo, izisombululo ze-HPMC zinokwenza ubungqingqwa okanye ukwahlukana kwinqanaba kumaqondo obushushu aphakamileyo, ngakumbi kugxininiso oluphezulu.

Kubalulekile ukuba uqaphele ukuba ngelixa i-HPMC inyibilikiswa emanzini, ireyithi kunye nobungakanani bokuphazamiseka ingahluka ngokuxhomekeka kwinqanaba elithile le-HPMC, kunye naziphi na ezinye izinto ezongezelelwayo kwinkqubo. Ukongeza, i-HPMC inokubonisa iimpawu ezahlukeneyo ze-solbabing kwiinyikima zezinto eziphilayo okanye ezinye iinkqubo ezingeyonto.

Ukunyibilisela i-HPMC emanzini kwenza ukuba ibe yi-polymer ebalulekileyo kwizicelo ezahlukeneyo apho uhlengahlengiso lwe-viscosity, ukuqulunqwa kwefilimu, okanye ezinye izinto ezinokusebenza zifunwa.