Kumasimi ezixhobo zenzululwazi kunye nolwakhiwo, i-conodities idlala indima ephambili ekwandiseni iimpawu ezahlukeneyo zezixhobo. I-HydroxyPOpyl Methylcelcelsulose (HPMC) yenye eyongeziweyo efumene ingqwalaselo ebonakalayo yokuphucula iipropathi ezinamathela kwizicelo ezahlukeneyo.
Izongezo yinxalenye ebalulekileyo yecandelo lezayensi zezixhobo kwaye zihlala zisetyenziswa ukuphucula iipropathi zezinto ezahlukeneyo. Phakathi kwezi zongezo, i-Hydroxypropyl Methylcelceltulose (HPMC) iye yaba ngumdlali obalulekileyo, ngakumbi ekuphuculeni iipropathi ezinamathela. Iipropathi ezinamathela zibalulekile kumashishini amaninzi, kubandakanya nolwakhiwo, amayeza kunye nokutya, apho amandla kunye nokutya, ukuqina kweqhina kuchaphazela kakhulu intsebenzo kunye nokuhlala kwemveliso.
1. Qonda i-hydroxypropyl methylcelcelculose (hpmc)
I-Hydroxypropyl Methylcelcelsele (i-HPMC) kukukhupha i-sellyulose kwaye kusetyenziswa ngokubanzi kumashishini ahlukeneyo ngenxa yepropathi yabantu abaninzi. Ihambelana nokutshintsha kweekhemikhali kweselutase, apho i-hydroxypropy ye-hydropyl kunye ne-methyl yamaqela aziswa kwi-selsebone. Olu tshintsho lunika iipropathi ezikhethekileyo, kubandakanya ukuzomala kwamanzi, amandla okwenza ifilimu, kwaye okona kubaluleke kakhulu, amandla okuphucula iipropathi zokunamathela.
2.Umatshini apho i-HPMC iphucula khona iipropathi ezinamathela
Ukukwazi kuka-HPMC ukuphucula iipropathi ezinamathela kwiziqu ezivela kwisakhiwo sayo semolekyuli kunye nokunxibelelana nezinye izinto. Xa inyibilikisiwe emanzini, iimolekyuli ze-HPMC Hydrate, zenza isisombululo se-viscous. Isisombululo sisebenza njenge-binder, sikhuthaza ukumila kobungqina obuqinileyo phakathi kwamasuntswana okanye umphezulu. Ukongeza, iimolekyuli ze-HPMC zinamaqela asebenzayo anokusebenzisana nomgangatho wamanzi, ukukhuthaza ukubambelela kunye nobumbano. Olu nxibelelwano lunceda ukuphucula ukumanzisa, ukusasazeka kunye nokunamathela phakathi kweendlela, ezizinto eziphambili ekufezekiseni iibhondi ezomeleleyo nezingapheliyo.
3. Ukusetyenziswa kwe-HPMC kwimizi-mveliso eyahlukeneyo
Ukusetyenziswa kwe-HPMC kwenza ukuba ixabiseke kakhulu kuluhlu olubanzi lwamashishini. Kwicandelo lezokwakha, i-HPMC isetyenziswa njengento eyongeziweyo kwizinto ezisekwe kwisamente ezinje ngodaka kunye nekhonkrithi. Ngokuphucula ulwalamano phakathi kwamasuntswana yesamente kunye ne-Aggregate, i-HPMC inyusa amandla, ukusebenza kunye nokuqina kwezi zinto. Ngokukwanjalo, kumzi-mveliso wamayeza, i-HPMC isetyenziswa kwifom yetafile ukuphucula ubudlelwane be-powder kwaye kuqinisekiswe ukukhutshwa ngamachiza. Ukongeza, kumzi-mveliso wokutya, i-HPMC isetyenziswa njengesiqhelo kunye ne-tickener, ukunceda ukuphucula ukuthungwa kunye nokubonisa ukufakwa ngelixa udlulisa ubomi beshelhesi yabo.
4. Isifundo setyala: Ukusetyenziswa kwe-HPMC
Ukuqhubela phambili ukusebenza ngempumelelo kwe-HPMC ekuphuculeni iipropathi zoku-bhan, izifundo ezininzi zinokuvavanywa. Kumzi-mveliso wokwakha, isifundo ngokusetyenziswa kwe-HPMC kwizinto zokuzimisela izikukhuni zibonisa ukonyuka okukhulu kumandla amakhulu kunye nokunganyanyeki. Ngokufanayo, kwifom yamayeza, izifundo zibonakalise ukuba iitafile eziqukethe i-HPMC Experries Accerties eziPhezulu kunye neeProfayili zokuZohlwaya xa kuthelekiswa neetafile ngaphandle kwe-HPMC. Ezi zifundo zibonisa ukuba ziluncedo kwi-HPMC kwizicelo zehlabathi, zigxininisa ukusebenza kwayo ekwandiseni iipropathi ezibambisayo kumashishini ahlukeneyo kwimizi mveliso eyahlukeneyo amashishini.
I-5. Ithemba lexesha elizayo kunye nemiceli mngeni
Ukuqhubela phambili, ukusetyenziswa kweezongezo ezinjenge-HPMC ukuphucula iipropathi zokwenzakala ezithenjiswe izithembiso eziqhubekayo kunye nezinto ezintsha. Inkqubela phambili kwiSayensi yeZandla kunye nezoBunjineli yeMichiza zinokukhokelela kuphuhliso lweezongezo ezintsha ngokusebenza okukhulu kunye nokungathathi ntweni. Nangona kunjalo, imiceli mngeni enjengeendleko zokusebenza, ukuzinza kwendalo kunye nokuthotyelwa kwendalo kufuneka kulungiswe ukuqinisekisa ukwamkelwa ngokubanzi kwabazali abasongelayo. Ukongeza, kuyafuneka ngakumbi uphando ukuze uqonde ngokupheleleyo iindlela zentshukumo kunye nokwandisa ukuqulunqwa nokusetyenziswa kweemveliso ezisekwe i-HPMC.
Izongezo ezinjenge-hydroxypropyl methylcelculose (i-HPMC) idlala indima ebalulekileyo ekuphuculeni umlinganiso. Ipropathi ye-Ding ichitha zonke iindlela zobomi. Ngesakhiwo sayo esahlukileyo semolekyuli kunye nonxibelelwano, i-HPMC ixhasa umbumbi, ukuhlangana kunye nokuxhotyiswa okuhlanganisiweyo, oko kwaqinisa ulwalamano phakathi kwamasuntswana okanye umphezulu. Ukusetyenziswa kwayo ngokuqatha kunye nokusebenza kwayo kwenza ukuba kungabinakho izicelo ezinjengokwakha, amayeza kunye nokutya. Njengoko uphando luqhubeke ukuqhubela phambili, ikamva libonelela ngamathuba amakhulu okwenza kwakhona kwaye isebenzise i-HPMC kunye nezongezo ezifanayo zokuphucula intsebenzo yokusebenza kunye nokuzibhuka kwezinto zobunjineli.
IXESHA LOKUQALA: FEB-28 ukuya ku-2424