I-HPMC okanye i-hydroxypropyl methylcelcelgalose yinto eguquguqukayo esetyenziswa kwimizi-mveliso eyahlukeneyo kubandakanya iintlobo zamayeza, cosmetics kunye nokutya. Isetyenziswe ngokubanzi njenge-thi cokener kunye ne-emulsifier, kunye neenguqu zayo zokubonisa kuxhomekeka kubushushu obutyhiliweyo. Kweli nqaku, siza kugxila kubudlelwane phakathi kwe-viscofity kunye neqondo lokushisa kwi-HPMC.
I-Viscosity ichazwa njengomlinganiso wentengo yokungasebenzi. I-HPMC yindawo eqinileyo eqinileyo yomlinganiselo omelanayo ixhomekeke kwizinto ezahlukeneyo, kubandakanya neqondo lobushushu. Ukuqonda ubudlelwane phakathi koVeksinity kunye neqondo lokushisa kwi-HPMC, kufuneka kuqala sazi ukuba injani na into kwaye yenziwe yintoni.
I-HPMC isuselwa kwi-sellulose, i-polymer yemvelo eyenzeka ngokwemvelo kwizityalo. Ukuvelisa i-HPMC, isellulose kufuneka iguqulwe ngekhemi kunye ne-propylene oxide kunye ne-methyl chloride. Ezi ziphumo zohlengahlengiso ekuqulunweni kwe-hydroxylpropy ye-hydroxyl kunye ne-methyl ekrokrisayo kwikhonkco leselfowuni. Isiphumo yinto eqinileyo eqinileyo enokuthi ichithwe kumanzi kunye nezinyibilikiweyo ze-organic kwaye isetyenziswa kwizicelo ezahlukeneyo, kuquka njengokuphazamiseka kweetafile kunye ne-arhente yokutya, phakathi kwezinye izinto.
I-vickosity ye-HPMC ixhomekeke ekugxinisweni kwento kunye nobushushu apho kuvezwa khona. Ngokubanzi, i-viscosity ye-HPMC ihla ngokukhulisa uxinzelelo. Oku kuthetha ukuba ukugxininisa okuphezulu kwe-HPMC kuphumela kwi-viscofis esezantsi kunye ne-vice verda.
Nangona kunjalo, ulwalamano olungenantlonelo phakathi kokufakwa kwi-viscosity kunye neqondo lobushushu luyinkimbinkimbi. Njengoko bekutshiwo ngaphambili, i-viscosity ye-HPMC inyuswa ngokunciphisa ubushushu. Oku kuthetha ukuba xa i-HPMC iphantsi kwamaqondo obushushu asezantsi, amandla ayo okuhambahamba ayancipha kwaye kuya kuba yi-vicous. Ngokukwanjalo, xa i-HPMC iphantsi kwamaqondo obushushu aphezulu, amandla ayo okuhamba kunyuke kwaye ukubonwa kwayo kuyancipha.
Kukho izinto ezahlukeneyo ezichaphazela ubudlelwane phakathi kobushushu kunye nokubonakala kwe-HPMC. Umzekelo, ezinye izisombululo ezikhoyo kulwelo zinokuchaphazela i-viscofity, njengoko inokwenzeka i-PH yolwelo. Ngokubanzi, nangona kunjalo, kukho ubudlelwane obungenambonakalo phakathi kwe-viscosity kunye neqondo lokushisa kwi-HPMC ngenxa yesiphumo seqondo lokushisa kwi-hydrogen bend kunye nokudibana kweemolekyuli zeeselfowuni kwi-HPMC.
Xa i-HPMC iphantsi kwamaqondo obushushu asezantsi, imixokelelwane yeselselose iba yingqongqo, ekhokelela ekunyukeni i-hydrogen. Ezi ntlobo ze-hydrogen zibangela ukunganyangeki kwento yokuqukuqela, ngaloo ndlela kunyusa ukubonwa. Kwelinye icala, xa ii-HPMCs zabekwa phantsi kwamaqondo obushushu aphezulu, imixokelelwane yeeselfowuni yaguquka ngakumbi, nto leyo eyakhokelela ekubeni bambalwa kakhulu amaqhina e-hydrogen. Oku kunciphisa ukunganyangeki kwento kuyahamba, kukhokelela kwi-viscofity esezantsi.
Kufanelekile ukuba uqaphele ukuba ngelixa kukho ubudlelwane obungenambonakalo phakathi kwe-viscofity kunye neqondo lokushisa le-HPMC, oku akusoloko kuyinto yazo zonke iintlobo ze-HPMC. Ubudlelwane obuthile phakathi kokufakwa kwi-viscofity kunye neqondo lokushisa lungahluka ngokuxhomekeka kwinkqubo yemveliso kunye nenqanaba elithile le-HPMC esetyenzisiweyo.
I-HPMC isetyenziswe ngokubanzi kumashishini ahlukeneyo kwizakhiwo zayo ezikhululekileyo kunye nokuzihlaziya iipropathi. I-viscosity ye-HPMC ixhomekeke kwizinto ezininzi, kubandakanya ukugxininiswa kwento kunye nobushushu apho kuvezwa khona. Ngokubanzi, i-viscosity ye-HPMC ihambelana ngokulinganayo kubushushu obufanelekileyo, okuthetha ukuba njengokuba iqondo lobushushu liyancipha, uVekyusi uyanda. Oku kungenxa yesiphumo seqondo lobushushu kwi-hydrogen ye-hydrogen kunye nokudibana kweemolekyuli zeeselula kwi-HPMC.
IXESHA LOKUQALA: UPE-08-2023