Yintoni umahluko phakathi kwamabakala ahlukeneyo e-HPMC?

I-HPMC (Hydroxypropyl Methylcelcelcelose) yi-InOinic selsulose i-Etherly isetyenziswe kwi-surmaceutical, ukutya, ukwakhiwa kunye ne-cosmetics. Amabakala ahlukeneyo e-HPMC ahlelwa ngokwendlela yabo yekhemikhali, iipropathi zomzimba, i-viscosity, isidanga sokufaka kunye nokusetyenziswa okwahlukileyo.

1. Isakhiwo samachiza kunye nesidanga sokufaka
Isakhiwo se-phuclor se-HPMC siquka amaqela e-hydroxyl kwikhonkco leselselose etshintshwa yi-Accordy kunye ne-hydroxypropoxy. Iipropathi zomzimba kunye neekhemikhali ze-HPMC zihluka ngokuxhomekeke kwinqanaba lokufakwa endaweni ye-FHISSY NE-hydroxypropoxy. Inqanaba lokufakelwa ngokuthe ngqo kuchaphazela ngqo ukuluka, uzinzo lobushushu kunye nomsebenzi we-HPMC. Ngokukodwa:

I-HPMC ene-mandosxy ye-up the the ukubonisa ubushushu obuphezulu be-thermal ye-thermal, eyenza ilungele ngakumbi kwizicelo ezibuthathaka zobushushu ezifana nokulawulwa kweziyobisi ezilawulayo.
I-HPMC ene-hydroxypropoxy yomxholo ongcono inomxholo ongcono wamanzi, kwaye inkqubo yayo yokuchithwa ayichaphazeli kubushushu, iyenza ilungele ukusetyenziswa kwiindawo ezibandayo.

I-2. Ibakala le-viscosity
UVICISITY yenye yezalathi ezibalulekileyo zeBanga le-HPMC. I-HPMC inoluhlu olubanzi lokuphila, ukusuka kwi-thensipepoise embalwa ukuya kumashumi amawaka e-punipoise. Ibanga lokubonisa ichaphazela ukusetyenziswa kwayo kwizicelo ezahlukeneyo:

I-VICMOTITY ye-HPMMC ephantsi (njenge-10-100 Mentipoise): Eli nqanaba le-HPMC lisetyenziswa ikakhulu kwizicelo ezifuna ukugcinwa okuncinci kunye nolwelo oluphezulu, iitafile, njl. Njl. ulwelo lwamalungiselelo.

I-vicminity ye-HPMMC (ezinje nge-100 ye-100 yeesenti): isetyenziswa ngokutya, amayeza e-cosmetics kunye namalungiselelo athile amayeza, anokusebenza njenge-gickener kwaye aphucule imveliso kunye nozinzo kwimveliso.

High viscosity HPMC (such as above 1000 centipoise): This grade of HPMC is mostly used in applications that require high viscosity, such as glues, adhesives and building materials. Banika amandla asemgangathweni obalaseleyo kunye nokumiswa.

I-3. Iipropathi zomzimba
Iipropathi zomzimba ze-HPMC, ezinjengokungabizi, ubushushu be-gesing, kunye nokuxhotyiswa kwamanzi, ukwahluka ngokwamanqanaba ayo:

Ukuluka: Uninzi lwe-HPMCs lube selutious elungileyo emanzini abandayo, kodwa i-solubity inciphisa njengoko umxholo weqhinganiso uyanda. Amanye amabakala akhethekileyo e-HPMC anokuchithwa kwiinyibilikisi eziphilayo kwizicelo ezithile zemizi-mveliso.

Iqondo lokuhlaselwa: Ubushushu be-HPMC kwisisombululo esinamandla siyahluka ngohlobo kunye nomxholo wezinto ezithengiweyo. Ngokubanzi, i-HPMC ene-mandoxy ye-upomesy ibeka i-geses kumaqondo obushushu aphezulu, ngelixa i-HPMC ene-hydroxypropoxy yomxholo ophakamileyo ibonisa ubushushu obuphantsi.

I-hygroscopity: i-HPMC ine-hygroscoficity, ngakumbi amabanga aphezulu angenayo. Oku kuyenza bagqwese kwiindawo ezifuna ukumelana nokufuma.

4. Iindawo zesicelo
Ngenxa yokuba amabakala ahlukeneyo e-HPMC anezinto ezahlukeneyo zomzimba kunye neekhemikhali, izicelo zabo kwimimandla eyahlukeneyo ziyafani:

Ishishini lamachiza: I-HPMC idla ngokusetyenziswa kwi-tayili yetafile, amalungiselelo okukhutshwa, amakhwenkwe, kunye namathyokhwe. I-HPMCECATION yeBanga le-HPMC kufuneka ifezekise imigangatho ethile ye-farmacopoeia, njenge-United States Pharmacopoeia (i-USP), e-European Pharmacopoeia (EP), njl. Njl.), Njl.
Umzi-mveliso wokutya: i-HPMC isetyenziswa njenge-thickener, i-enulsifier, i-stabilimizer kunye nefilimu yangaphambili. I-HPMC yeBanga le-HPMC ihlala ifunwa ukuba ingenzi buhlungu, engenaxabiso, i-odols, kwaye ifuna ukuthobela imigaqo yolonga yokutya, njengezo ze-US
Ishishini lokwakha: I-HPMC ye-HPMC yokwakha isetyenziswa ikakhulu kwizixhobo ezisekwe ikakhulu kwizixhobo ezisekwe kwizamente, iimveliso ze-gypsim kunye neemveliso ze-gypsum kunye neengubo zibetha, zigcine amanzi, zithahlise kwaye ziphucule. I-HPMC yamabanga ahlukeneyo e-viscosity inokuchaphazela ukusebenza kwezinto zokwakha kunye nokusebenza kwemveliso yokugqibela.

5. Imigangatho esemgangathweni kunye neMigaqo
Amabakala ahlukeneyo e-HPMC akwaxhomekeke kwimigangatho yenqanaba eliqhelekileyo kunye nemigaqo:

I-HPMCICATION yeBanga le-HPMC: kufuneka idibane neemfuno ze-phammacopoeia, njenge-USP, ep, njl njl.
I-HPMC yeBanga le-HPMC: Kuya kufuneka ihambelane nemigaqo efanelekileyo kwizicelo zokutya ukuqinisekisa ukhuseleko lwayo kukutya. Amazwe ahlukeneyo kunye nemimandla inokuba neenkcukacha ezahlukeneyo ze-HPMC yeBanga le-HPMC.
I-HPMP ye-HPMPRE -CMC: I-HPMC esetyenzisiweyo ekwakhiweni, i-HPMC isetyenziswa ekwakhiweni, i-HPMC kunye neminye imimandla ibingadingi ukuthobela ukutya okanye imigangatho yeziyobisi, kodwa kusafuneka ikwazi ukuhlangabezana nemigangatho ehambelana nemizi mveliso, njengemigangatho yemveliso ye-ISO.

I-6. Ukhuseleko lwendalo
I-HPMC yamabakala ahlukeneyo ikwahluke ngokupheleleyo kukhuseleko kunye nokhuseleko lwendalo. I-HPMOCE-CAGMC idla ngokuvavanywa ngokukhuselekileyo kukuqinisekisa ukuba ayinabungozi emzimbeni womntu. I-HPMP ye-HPMP eSebenzayo, kwelinye icala, ihlawula ingqalelo engakumbi ekukhuseleni kwendalo esingqongileyo kunye nokuhlanjwa ngexesha lokusebenza ukunciphisa ifuthe kwindalo esingqongileyo.

Umahluko phakathi kwamabakala ohlukeneyo e-HPMC iboniswa ikakhulu kubume bemichiza, i-viscosity, iipropathi zemfundo, iindawo zesicelo, imigangatho esemgangathweni kunye nokhuseleko. Ngokweemfuno ezithile zesicelo, ukukhetha inqanaba elifanelekileyo le-HPMC kunokuphucula kakhulu ukusebenza kunye nomgangatho wemveliso. Xa kuthengwa i-HPMC, ezi zinto kufuneka kuthathelwe ingqalelo ngokupheleleyo ukuqinisekisa ukusebenza kunye nokusebenza kwemveliso.