IHydroxypropyl Methylcellulose (HPMC) iphuma kwi cellulose esetyenziswa kakhulu ekutyeni, kumayeza, kulwakhiwo nakwizithambiso. Imodeli yayo ethile ye-E15 iye yatsala ingqalelo enkulu ngenxa yeempawu zayo ezizodwa kunye nokusetyenziswa okubanzi.
1. Iimpawu zomzimba kunye neekhemikhali
Ukuqulunqwa kweekhemikhali
I-HPMC E15 iyingxenye ye-methylated kunye ne-hydroxypropylated cellulose ether, isakhiwo sayo se-molecular iqukethe amaqela e-hydroxyl kwi-cellulose molekyuli endaweni ye-methoxy kunye ne-hydroxypropyl. I-"E" kwimodeli ye-E15 imele ukusetyenziswa kwayo okuphambili njenge-thickener kunye ne-stabilizer, ngelixa i-"15" ibonisa ukucaciswa kwayo kwe-viscosity.
Imbonakalo
I-HPMC E15 idla ngokuba ngumgubo omhlophe okanye omhlophe ongenavumba, ongenancasa kunye neepropati ezingenayo ityhefu. Amasuntswana alo alungile kwaye anyibilika ngokulula emanzini abandayo kunye nashushu ukwenza isisombululo esicacileyo okanye esincinci.
Ukunyibilika
I-HPMC E15 inokunyibilika kakuhle kwamanzi kwaye inokunyibilika ngokukhawuleza emanzini abandayo ukwenza isisombululo kunye ne-viscosity ethile. Esi sisombululo sihlala sizinzile kumaqondo okushisa ahlukeneyo kunye nokugxininiswa kwaye asichatshazelwa lula kwimeko yangaphandle.
Viscosity
I-E15 inoluhlu olubanzi lwe-viscosity. Ngokuxhomekeke kusetyenziso lwayo oluthile, i-viscosity efunwayo inokufumaneka ngokulungelelanisa ugxininiso kunye nobushushu besisombululo. Ngokuqhelekileyo, i-E15 ine-viscosity malunga ne-15,000cps kwisisombululo se-2%, esenza ukuba isebenze kakuhle kwizicelo ezifuna i-viscosity ephezulu.
2. Iipropati ezisebenzayo
Isiphumo sokutyeba
I-HPMC E15 sisityebi esisebenza kakuhle kwaye sisetyenziswa ngokubanzi kwiinkqubo ezahlukeneyo zamanzi. Inokunyusa kakhulu i-viscosity ye-liquid, inikeze i-thixotropy egqwesileyo kunye nokumiswa, kwaye ngaloo ndlela iphucule ukuthungwa kunye nokuzinza kwemveliso.
Isiphumo sokuzinzisa
I-E15 inozinzo oluhle, olunokuthintela ukuchithwa kunye ne-agglomeration yamasuntswana kwinkqubo ehlakaziweyo kunye nokugcina ukufana kwenkqubo. Kwinkqubo ye-emulsified, inokuzinzisa i-oil-water interface kunye nokuthintela ukuhlukana kwesigaba.
Ipropati yokwenza ifilimu
I-HPMC E15 ineempawu ezigqwesileyo zokwenza ifilim kwaye inokwenza iifilimu eziqinileyo, ezicacileyo kumphezulu we substrates ezahlukeneyo. Le filimu inokuguquguquka okuhle kunye nokubambelela kwaye isetyenziswa ngokubanzi kwiingubo zamayeza, ukutya okunokutya, kunye neengubo zokwakha.
Ipropati yokufuma
I-E15 inamandla okuthambisa kwaye ingasetyenziswa njengento yokuthambisa kwizithambiso kunye neemveliso zokunakekelwa kwesikhumba ukugcina ulusu lufumile kwaye lugudile. Kushishino lokutya, isenokusetyenziswa njengesigcini-manzi sokwandisa ixesha leshelufu lokutya.
3. Iinkalo zesicelo
Ishishini lokutya
Kushishino lokutya, i-HPMC E15 ihlala isetyenziswa njenge-thickener, stabilizer kunye ne-emulsifier. Ingasetyenziselwa ukuvelisa i-ayisikrimu, ijeli, iisosi kunye neemveliso zepasta, njl., ukuphucula incasa kunye nokuthungwa kokutya kunye nokwandisa ubomi bayo beshelufu.
Ishishini lamachiza
I-HPMC E15 isetyenziswa ngokubanzi kumalungiselelo amayeza kwishishini lamachiza, ngakumbi njengeyona nto iphambili yokukhutshwa okulawulwayo kunye neepilisi eziqhubekayo zokukhululwa. Inokulawula izinga lokukhululwa kweziyobisi kunye nokuphucula ukuzinza kunye nokuqina kokusebenza kweziyobisi. Ukongezelela, i-E15 isetyenziselwa ukulungiswa kwe-ophthalmic, i-ointments ye-topical kunye ne-emulsions, njl., kunye ne-biocompatibility efanelekileyo kunye nokhuseleko.
4. Ukhuseleko kunye nokukhuselwa kwendalo
I-HPMC E15 yi-derivative ye-cellulose engeyiyo ityhefu kwaye ayicaphukisi kunye nokuhambelana kakuhle kwe-biocompatibility kunye nokhuseleko. Isetyenziswa ngokubanzi kwiinkalo zokutya kunye namayeza kwaye ihlangabezana nemigangatho efanelekileyo yokhuseleko kunye neemfuno zokulawula. Ukongeza, i-E15 ine-biodegradability elungileyo kwaye ayiyi kungcolisa imo engqongileyo, ehlangabezana neemfuno zoluntu lwanamhlanje kwizinto eziluhlaza kunye nokusingqongileyo.
I-Hydroxypropyl methylcellulose E15 iye yaba yinto ebalulekileyo yokongeza kumashishini ahlukeneyo ngenxa yeempawu zayo ezizodwa kunye neekhemikhali kunye noluhlu olubanzi lwezicelo zokusebenza. Inokuqina okugqwesileyo, ukuzinzisa, ukwenza ifilimu kunye neempawu zokuthambisa kwaye isetyenziswa kakhulu kukutya, amayeza, ukwakhiwa kunye nezithambiso. Kwangaxeshanye, i-E15 inokhuseleko olulungileyo kunye nokukhuselwa kokusingqongileyo, kwaye iyinto eluhlaza eyimfuneko kwishishini lanamhlanje.
Ixesha lokuposa: Jul-27-2024