Hydroxypropyl methylcelculose (hpmc)Ngaba i-ionic ye-ionsulose isetyenziswe ngokubanzi kwizakhiwo, amayeza, ukutya, izixhobo ze-cosmetics kunye namanye amashishini. Ezona zikhombisi ziphambili ze-HPMC zibandakanya iipropathi zomzimba kunye neekhemikhali, ukuluka, ukugcinwa, isidanga sokufaka endaweni, njl.
1. Imbonakalo kunye neempawu ezisisiseko
I-HPMC idla ngokuba ngumgubo omhlophe okanye ongekho mhlophe, ongenakuthelekiswa nanto, ongenaxabiso, engenabungozi, enozinzo oluhle kunye nozinzo. Inokusasazeka ngokukhawuleza kwaye inyibilike emanzini ebandayo ukwenza isisombululo esibonakalayo okanye kancinci isisombululo se-colbid, kwaye inamandla okuzala okumbi kwiinyibilikisi.
2. I-Viscosity
UVICISITY yenye yezona zinto zibalulekileyo ze-HPMC, ezigqiba ukusebenza kwe-gancescl®hpmc kwizicelo ezahlukeneyo. I-viscosity ye-HPMC iphawulwa njengesisombululo se-2% kwi-20 ° C, kwaye uluhlu oluqhelekileyo lokuloba luvela kwi-5 MPAF ku-MPAF ukuya kuma-2000 000. Ukuphelisa i-viscofity, ukomelela kwesiphumo esihle kakhulu sesisombululo kunye nokungcono. Xa isetyenziswa kumashishini anjengokwakha kunye namayeza, ibanga elifanelekileyo le-viscocity kufuneka ikhethwe ngokweemfuno ezithile.
I-3. I-Accopy kunye ne-hydroxypropoxy yomxholo
Iipropathi zeekhemikhali ze-HPMC zimiselwa ikakhulu yi-APEXYY (-och₃) kunye ne-Hydroxypropoxy (-och₂hhchch₃) izixhobo zokufakwa ngaphakathi. I-HPMC enezidima ezahlukeneyo ezibonisa ukulimaza okwahlukileyo, umsebenzi womphezulu kunye neqondo lobushushu.
Umxholo we-APEXGY: Ngokwesiqhelo phakathi kwe-19.0% ne-30.0%.
Umxholo weHydroxypropoxy: Ngokwesiqhelo phakathi kwe-4.0% ne-120%.
4. Umxholo wokufuma
Umxholo wokufuma kwe-HPMC ulawulwa ngokubanzi kwi-≤5.0%. Umxholo ophezulu wokufuma kuya kuchaphazela uzinzo kunye nokusetyenziswa kwemveliso yemveliso.
5. Umxholo we-Ash
I-Ash yintsalela emva kokuba i-HPMC itshisiwe, ubukhulu becala isuka kwi-inots ye-inorganic esetyenziswe kwinkqubo yemveliso. Umxholo we-Ash uhlala ulawulwa kwi-¶1.0%. Umxholo ophezulu kakhulu unokuchaphazela ukucaca kunye nokucoceka kwe-HPMC.
I-6. Ukungasebenzi kunye nokungafihli
I-HPMC inomhlaba olungileyo kwaye unokukhawuleza uchithe amanzi abandayo ukwenza isisombululo se-colloidal efanayo. Ukucaca kwesisombululo kuxhomekeke kubunyulu be-HPMC kunye nenkqubo yayo yokuchitha. Isisombululo esikumgangatho ophezulu we-HPMC sihlala singenabala okanye kancinci i-milyy.
I-7. Ubushushu be-gel
Isisombululo se-HPMC ACTEAUCTIONAL siya kwenza ijeli kubushushu obuthile. Iqondo lokushisa layo lihlala liphakathi kwama-50 nama-90 ° C, kuxhomekeke kumxholo we-AFCHY NOHCHDOXPOXY. I-HPMC ene-EPEXITY UMGAQO-NKQUBO Unobushushu obuphezulu we-gel, ngelixa i-HPMC ineqondo eliphezulu le-hydroxypropoxy inamaqondo obushushu asezantsi.
8. Ixabiso le-pH
Ixabiso le-pH ye-Incelcel®HPMC AMANQAKU EXABISO phakathi kwe-5.0 ne-8.0, engathathi hlangothi okanye ebuthathaka i-alkaline kwaye ilungele iintlobo ezahlukeneyo zezicelo.
I-9. Ubungakanani be-paunticle
Ukulunga kwe-HPMC kubonakaliswa ngokubanzi njengepesenti edlula kwi-80-mesh okanye i-100-mesh screen. Ihlala ifunwa ukuba ≥98% idlulise kwi-8-mesh screen se-mesh ukuqinisekisa ukuba ineentsali ezifanelekileyo kwaye isetyenziswe xa isetyenziswa.
I-10. Umxholo wesinyithi onzima
Umxholo wesinyithi onzima (njengokukhokela kunye ne-arsenic) ye-HPMC kufuneka ihambelane nemigangatho efanelekileyo yeshishini. Ngokwesiqhelo, umxholo okhokelayo yi-≤10 i-PPM kunye nomxholo we-Arsenic yi-≤3 PPM. Ingakumbi ekutyeni kunye neBanga le-HEMMC ye-HPMC, iimfuno zomxholo wesinyithi onzima ziyinto engqongqo.
11. Izalathisi ezincinci
Kwinqanaba le-PARMACEOCAL NOKOKUFAYI IBAKALA LENKULUMBUSO YOKUGQIBELA, INDLELA YOKUZIPHATHA KAKHULU KUFUNEKA UQEQESHWE, kubandakanya nokubalwa kombane, ukubumba, i-Goli, e-E.
I-Colony Colony Colony Colony i-CF1000 CFU / G
Iyonke i-fold kunye ne-Yeast Count ≤100 CFU / G
E. Coli, Salmonella, njl. Njl. Akufumaneki
12. Iindawo ezisetyenzisiweyo
I-HPMC isetyenziswe ngokubanzi kumashishini amaninzi ngenxa yokugcinwa kwayo, ukugcinwa kwamanzi, ukwenziwa kwefilimu, i-ilutissation, i-inlissations kunye nezinye iipropathi:
Umzi mveliso wokwakha: Njengomntu obambeleyo kunye nokugcinwa kwamanzi e-Creating Cementi, i-Potimer Plewder, I-Todty Polder, I-Tile Adheetive Ceative ukhathalelo lokwakha.
Umzi-mveliso wamachiza: Isetyenziswe njengempahla yokuhlambela, yokukhupha, kunye ne-capsule ye-capsule gowthi yetafile yeziyobisi.
Ishishini lokutya: Isetyenziswe njengo-Emoulsifier, i-stabilizer, i-tickener, esetyenziswa eJelly, i-golly, iimpahla ezibhakiweyo, njl.
Umzi mveliso weekhemikhali zemihla ngemihla: Isetyenziswe njenge-thickener kunye ne-emulsifitizer kwiimveliso zonyango, iingcingo, kunye nee-shampoos.
Iimpawu zobugcisa zeI-HPMCQuka i-viscofity, isidanga sokufakwa endaweni (umxholo weqela le-hydrolyzed), umbandela we-hydrolyzded, i-ash, umxholo we-pl, umxholo we-hleyo, umxholo we-hleyo, umxholo wesinyithi, njl. njl. Xa ukhetha i-HPMC, abasebenzisi mabachonge iinkcazo ezifanelekileyo ngokweemfuno ezithile zesicelo ukuqinisekisa ezona ziphumo zisetyenziswayo.
IXESHA LOKUQALA: FEB-11 ukuya ku-1125