Yenziwe ngantoni iHPMC?

IHydroxypropyl methylcellulose (HPMC) yipolymer eguquguqukayo evela kwi-cellulose, i-polysaccharide yendalo efumaneka kwiindonga zeseli zezityalo. Isetyenziswa ngokuqhelekileyo kumashishini ahlukeneyo afana namayeza, ukutya, izimonyo, ukwakhiwa, kunye nokunye ngenxa yeempawu zayo ezizodwa.

I-HPMC idityaniswe ngokuguqula imichiza yeselulosi ngokusabela kwe-etherification. Ngokukodwa, iveliswa ngokunyanga i-cellulose ngendibaniselwano yepropylene oxide kunye ne-methyl chloride ukwazisa amaqela e-hydroxypropyl kunye ne-methyl kumqolo we-cellulose. Le nkqubo iphumela kwipolymer enyibilikayo emanzini eneempawu eziphuculweyo xa kuthelekiswa neselulosi yendalo.

Inkqubo yeMveliso:

Ukuveliswa kweHPMC kubandakanya amanyathelo amaninzi:

I-Cellulose Sourcing: I-Cellulose, efumaneka kwi-pulp yomthi okanye umqhaphu, isebenza njengesiqalo.

I-Etherification: I-Cellulose idlula i-etherification, apho ithatha i-propylene oxide kunye ne-methyl chloride phantsi kweemeko ezilawulwayo ukuzisa i-hydroxypropyl kunye namaqela e-methyl.

Ukucoca: Imveliso ephumayo ithatha amanyathelo okucoca ukususa ukungcola kunye neemveliso ezingafunekiyo.

Ukomisa kunye nokugaya: I-HPMC ecocekileyo yomiswa kwaye igaywe ibe ngumgubo ocolekileyo okanye iigranules, kuxhomekeke kwisicelo esifunwayo.

I-HPMC ibonisa uluhlu olubanzi lweepropati, iyenza ilungele izicelo ezahlukeneyo:

Ukunyibilika kwamanzi: I-HPMC inyibilika emanzini abandayo, yenza izisombululo ezicacileyo, ezibonakala. I-solubility inokulungelelaniswa ngokuguqula i-degree of substitution (DS) ye-hydroxypropyl kunye namaqela e-methyl.

Ukwenziwa kweFilimu: Inokwenza iifilimu eziguquguqukayo kunye nezidibeneyo xa zomisiwe, ziyenze zilungele ukufakwa kwezicelo kumayeza kunye namashishini okutya.

Ukujiya: I-HPMC yi-arhente esebenzayo yokuqina, ibonelela ngolawulo lwe-viscosity kwimixube eyahlukeneyo efana nokuthambisa, iikhrimu, kunye neepeyinti.

Ukuzinza: Ibonisa ukuzinza kweekhemikhali okugqwesileyo kunye nokuchasana nokuthotywa kwe-microbial.

Ukuhambelana: I-HPMC iyahambelana noluhlu olubanzi lwezinye izithako, kuquka i-surfactants, iityuwa, kunye nezithinteli.

I-HPMC ifumana izicelo ezininzi kumashishini ahlukeneyo:

I-Pharmaceuticals: Isetyenziswa ngokuqhelekileyo njenge-binder, i-agent-coating agent, i-viscosity modifier, kunye ne-matrix eqhubekayo yokukhululwa kwi-tablet formulations.

Ishishini lokutya: I-HPMC isebenza njengento etyebisayo, isizinzisi, kunye ne-emulsifier kwiimveliso zokutya ezifana neesosi, izinxibo, kunye nezimuncumuncu.

Ulwakhiwo: Kushishino lokwakha, i-HPMC isetyenziswa njengento etyebisayo kwiimveliso ezisekwe kwisamente, ukuphucula ukusebenza kunye nokuncamathela.

Iimveliso zoNonophelo loBuqu: Ifumaneka kwizinto zokuthambisa, iishampu, kunye nentlama yamazinyo njenge-agent ejiyayo, i-emulsifier, kunye nefilimu yangaphambili.

Ipeyinti kunye neeNgqungquthela: I-HPMC iphucula iimpawu ze-rheological zepeyinti kunye neengubo, ziphucula ukusetyenziswa kwazo kunye nokusebenza.

I-HPMC, ephuma kwiselulosi ngokusabela kwe-etherification, yipolymer eguquguqukayo eneenkqubo ezahlukeneyo kumashishini ohlukeneyo. Iimpawu zayo ezikhethekileyo, ezinjengokunyibilika kwamanzi, amandla okwenza ifilimu, kunye neempawu ezityebileyo, ziyenza ibaluleke kakhulu kumayeza, ukutya, ulwakhiwo kunye neemveliso zokhathalelo lomntu.