Yintoni i-hypromellose esetyenziswa kwiitafile?

I-Hypromellose, ekwabizwa ngokuba yi-hydroxypropyl methylcelculose (i-HPMC), isetyenziswa ngokukodwa kwifom yetafile ngeenjongo ezininzi:

1. I-Binder: i-HPMC ihlala isetyenziswa njenge-binder kwifom yetafile ukubamba izithako ezisebenzayo (APIS) kunye nabanye abanolo. Njengomthi we-binder, i-HPMC inceda ekwenzeni amacwecwe ahlanganayo ngamandla aneleyo, aqinisekisa ukuba ithebhulethi igcina ingqibelelo ngexesha lokuphatha, ukupakisha kunye nokugcina.
2. Intsholongwane: Ukongeza kwiipropathi zayo ezibophelelayo, i-HPMC inokusebenza njenge-suinterper kwiitafile. I-diationgrans inceda ekukhuthazeni ukwahlukana ngokukhawuleza okanye ukwahlula-hlulwa kwethebhulethi kwi-Intembeko, ukuqhuba ukukhululwa kwamachiza kunye nokuthathwa kwe-gestrointenal phecanal. I-HPMC ishukuma ngokukhawuleza xa uqhagamshelane namanzi, ekhokelela ekuqhawukeni kwetafile kumasuntswana amancinci kunye nokunceda ukupheliswa kweziyobisi.
3. Ifilimu yangaphambili / iarhente yokuhamba-nye: i-HPMC inokusetyenziswa njengearhente yefilimu okanye i-filting yempahla yeetafile. Xa isetyenziswa njengefilimu emnyama kumphezulu wecwecwe, i-HPMC inceda ekuphuculeni imbonakalo, ukunqunyulwa, kunye nokuzinza kwecwecwe. Ingasebenza njengesithintelo ukukhusela ithebhulethi ukusuka ekrwada, ukukhanya, kunye negesi yase-Atmospheric, ngaloo ndlela kuphuculwe isherifu-ubomi bechiza.
4. IMatrix yangaphambili: Ukulawulwa-ukukhululwa okanye ukukhululwa kwethebhulethi yethebhulethi, i-HPMC ihlala isetyenziswa njengematrix yangaphambili. Njenge-matrix yangaphambili, i-HPMC ilawula ukukhululwa kwechiza ngokwenza i-matrix efana ne-matrix ejikeleze i-API, elawula inqanaba lokukhupha ixesha elide. Oku kuvumela ukuhanjiswa kweziyobisi kunye nokuphuculwa koguli ngokuphuculwa kwesigulo se-doad.
5. Unomdla: I-HPMC inokusetyenziswa njengokhetho lweefom zethebhulethi ukuguqula iipropathi zecwecwe, ezifana nobunzima, ubunzulu, kunye nexabiso lokuchitha. Iipropathi zayo eziguquguqukayo zenza ukuba zilungele ukusetyenziswa kwiinkqubo ezahlukeneyo, kubandakanya ukukhutshwa kwangoko, ukukhutshwa okulibazisayo, kunye neetafile zokukhutshwa kwawo.

Ngokubanzi, i-HPMC yindlela esetyenziswa ngamayeza ngokubanzi kwiifomu zecwecwe ngenxa ye-biomitiatib ye-biomatise, yokuqalisa, kunye nokuphumelela ekufezekiseni iipropathi zetafile ezinqwenelekayo. Imeko yayo yabantu abaninzi ivumela iifomuli zokwenza ifomu lebhulukhwe yetafile yokufezekisa iimfuno ezithile zokuhambisa iziyobisi kunye neemfuno zesigulana.