Yeyiphi i-adming inokuphucula ukuqina kwekhonkrithi? (I-HPMC)

I-HydroxypropyTylMethylcelcelcelcelcelcelcelcelcelcelcelcelcelcelcelcelcel Ngelixa isenokungaphuculi ngokuthe ngqo ukuqina kwekhonkrithi, idlala indima ebalulekileyo ekuphuculeni iipropathi ezahlukeneyo zomxube wekhonkrithi.

1. Intshayelelo

I-HydroxyPOpyl Methylcelcelculose Ngenxa yepropathi yayo eyahlukileyo, isetyenziswa ngokubanzi njengesongezo kwizinto zokwakha. Kwikhonkrithi, i-HPMC isetyenziswa njengearhente yokugcina amanzi, i-thi cokener, kunye ne-binder. Isakhiwo sayo semichiza siyinceda ukuba senze ifilimu yokukhusela ejikeleze amasuntswana e-ceace, echaphazela iipropathi ze-RToology kunye noomatshini bomxube wekhonkrithi.

2. Indima ye-HPMC kwiQonga lePrimete:

Ukugcinwa kwamanzi kunye nokusebenza:

I-HPMC isebenza njengearhente yokugcina amanzi, ukuthintela ukulahleka kwamanzi ngokungaphaya kwamanqanaba okuqala okuphilisa ikhonkrithi.
Olu gcino lwamanzi luphuculo lwamanzi lunceda ukugcina ukuphumelela ngokufanelekileyo, kukhokelela ekubekweni okuthe kratya kunye nokuqulunqwa kwekhonkrithi.

Yongeza ububi:

Iprophathi yefilimu yefilimu ye-HPMC inceda ukuphucula ububi phakathi kwesamente, okukhokelela kwi-matrix yekhonkrithi enesidima.

Ukunciphisa ukwahlulwa kunye nokopha:

I-HPMC inceda ukunciphisa umngcipheko wokwahlula kunye nokopha kwikhonkrithi, kukhokelela kwimveliso eninzi, yesakhiwo.

Ixesha elifanelekileyo lokuseta:

Ukusetyenziswa kwe-HPMC kunokuba nefuthe kwixesha lekhonkrithi, ngaloo ndlela kubonelela ngolungelelwaniso phakathi kokuphuculwa kwamandla okukhawulezileyo.

Iziphumo kwiipropathi zoomatshini:

Ngelixa i-HPMC ngokwayo ayinakuphucula ngokuthe ngqo ukuqina kwekhonkrithi, isiphumo sayo sokusebenza kunye nokunamathela ngokungathanga ngqo kuchaphazela ngokuthe ngqo iipropathi zekhonkrithi, ukunceda ukwahlula izakhiwo ezomeleleyo nezomeleleyo.

3. Amanqaku kunye neendlela ezilungileyo:

Ulawulo lweDosage:

I-dosage echanekileyo ye-HPMC ibalulekile. Ukuzithoba kunokubangela iziphumo ezibi, ngelixa i-Deresing isenokunganikezeli kuphuculo olufunekayo.

Ukuhambelana:

Ukuhambelana nolunye uhlobo lwekhonkrithi kunye nezixhobo kufuneka kuthathelwe ingqalelo ukuphepha nakuphi na ukuphendula okuchaseneyo okunokuphazamisa iipropathi zomxube wekhonkrithi.

Indlela yokunyanga:

Nangona i-HPMC inceda ukugcina amanzi, iindlela ezifanelekileyo zokunyanga kufuneka zisetyenziselwe ukuqinisekisa ukuqina kwexesha elide kwikhonkrithi.

Nangona i-HPMC ayisiyo iarhente ethe ngqo ephucula ukuqina kwekhonkrithi, ukusetyenziswa kwayo kumxube wekhonkrithi kunokuphucula ukusebenza, i-adhesion kunye nezinye iipropathi, ngaloo ndlela kuthathe ngokungathanga ngqo kokuqina kwezakhi zekhonkrithi. I-HPMC kufuneka ithathwe njengenxalenye yendlela edityanisiweyo yokudibanisa ikhonkrithi kunye neendlela zokwakha zokufezekisa izakhiwo ezomeleleyo nezilomeleleyo.