Ukulethwa okusheshayo Ukugcinwa Kwamanzi Okuphezulu Kwekhwalithi Ephezulu kanye ne-HPMC Ye-Viscosity Ephakeme Yokwakha
thobela inkontileka”, ihambisana nemfuneko yemakethe, ijoyina ngenkathi isemqhudelwaneni wemakethe ngekhwalithi yayo ephezulu kanye nokuhlinzeka ngosizo olubanzi kakhulu nolukhethekile kubathengi ukuze babavumele bathuthuke babe abawinile ababalulekile. Ukuphishekela enkampanini, kuzoba ukwaneliseka kwamakhasimende ukulethwa Okushesha Ukugcinwa Kwamanzi Ekhwalithi Ephezulu kanye ne-High Viscosity I-HPMC-Isixazululo esihle samanani Okwakha, Sizonikeza izixazululo ezinhle kakhulu zokuqalisa kanye nekhwalithi ephezulu. ukuzuza ezinhlelweni zethu eziphelele ngokusithinta namuhla.
thobela inkontileka”, ihambisana nemfuneko yemakethe, ijoyina ngenkathi ikumncintiswano wemakethe ngekhwalithi yayo ephezulu kanye nokuhlinzeka ngosizo olubanzi kakhulu nolukhethekile kubathengi ukuze babavumele bathuthuke babe abawinile ababalulekile. Ukuphishekela enkampanini, kuzoba ukwaneliseka kwamakhasimendeI-China Coating Auxiliary Agents kanye Nezinto Zokwakha, Ithini intengo enhle? Sinikeza amakhasimende ngentengo yefekthri. Esimweni sekhwalithi enhle, ukusebenza kahle kudinga ukunakwa futhi kugcinwe inzuzo efanele ephansi nenempilo. Kuyini ukulethwa okusheshayo? Senza ukulethwa ngokwezidingo zamakhasimende. Nakuba isikhathi sokulethwa sincike enanini le-oda nobunkimbinkimbi balo, sisazama ukuhlinzeka ngezinto ngesikhathi. Ngethemba ukuthi singaba nobudlelwano bebhizinisi besikhathi eside.
Incazelo Yomkhiqizo
IHydroxypropyl Methyl Cellulose(HPMC)
I-Molecular Formula
I-Hypromellose (Hydroxypropylmethylcellulose: HPMC) uhlobo lokufaka esikhundleni 2910, 2906, 2208 (USP)
Izakhiwo Zomzimba
- Impushana emhlophe noma ephuzi emhlophe
- Incibilika ku-solvent exubile yemvelo noma enamanzi
- Ukwenza ifilimu esobala lapho kususwa i-solvent
- Akukho ukusabela kwamakhemikhali nesidakamizwa ngenxa yempahla yayo engeyona i-ionic
- Isisindo samangqamuzana: 10,000 ~ 1,000,000
Iphuzu leGel: 40 ~ 90 ℃
- Indawo yokuthungela ngokuzenzakalelayo: 360 ℃
IHydroxypropyl Methylcellulose (HPMC) Ibanga Lemithi i-Hypromellose excipient kanye nesengezo, esingasetshenziswa njenge-thickener, dispersant, emulsifier kanye ne-ejenti yokwakha ifilimu.
I-QualiCell Cellulose ether iqukethe i-methyl cellulose (USP, EP,BP,CP) kanye nezinhlobo ezintathu zokufakwa esikhundleni se-hydroxypropyl methyl cellulose (hypromellose USP, EP,BP,CP) ngayinye etholakala ngamabanga amaningana ahlukene nge-viscosity. Izitifiketi ze-Halal.
Enqubweni yokukhiqiza, ukotini wemvelo ohlanjululwe kakhulu ufakwa etherified nge-methyl chloride noma ngenhlanganisela ye-methyl chloride ne-propylene oxide ukuze kwakheke i-ether encibilika emanzini, engeyona ionic cellulose. Azikho izinsiza zezilwane ezisetshenziswa ekukhiqizweni kwe-HPMC.HPMC engasetshenziswa njengesihlanganisi kumafomu omthamo oqinile njengamaphilisi nama-granules. Iphinde isebenze imisebenzi ehlukahlukene, njengezibonelo, ekuthuthukiseni ukugcinwa kwamanzi, ukuqina, ukusebenza njenge-colloid evikelayo ngenxa yomsebenzi wayo ongaphezulu, ukukhululwa okuqhubekayo, nokwakheka kwefilimu.
I-QualiCell HPMC inikeza imisebenzi ehlukahlukene njengokugcinwa kwamanzi, i-colloid evikelayo, umsebenzi ongaphezulu, ukukhululwa okuqhubekayo. Kuyinhlanganisela engeyona i-ionic imelana nokukhipha usawoti ngaphandle futhi izinzile phezu kwebanga elibanzi le-pH. Izinhlelo ezijwayelekile ze-HPMC ziyi-binder kumafomu omthamo oqinile njengamaphilisi nama-granules noma ukuqina kwezinhlelo eziwuketshezi.
I-Pharma HPMC iza ngobubanzi obuhlukahlukene be-viscosity kusuka ku-3 kuye ku-200,000 cps, futhi ingasetshenziswa kabanzi ukuhlanganisa ithebhulethi, imbudumbudu, ibhinder, i-thickener, stabilizer nokwenza i-capsule yemifino ye-HPMC.
Ukucaciswa Kwekhemikhali
| I-Hypromelose Ukucaciswa | 60E( 2910) | 65F( 2906) | 75K( 2208) |
| Izinga lokushisa lejeli (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| I-Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| I-Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Ibanga Lomkhiqizo
| I-Hypromelose Ukucaciswa | 60E( 2910) | 65F( 2906) | 75K( 2208) |
| Izinga lokushisa lejeli (℃) | 58-64 | 62-68 | 70-90 |
| I-Methoxy (WT%) | 28.0-30.0 | 27.0-30.0 | 19.0-24.0 |
| I-Hydroxypropoxy (WT%) | 7.0-12.0 | 4.0-7.5 | 4.0-12.0 |
| I-Viscosity(cps, 2% Solution) | 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000 | ||
Isicelo
I-Pharma Grade HPMC inika amandla ukukhiqizwa kokwakhiwa kokukhishwa okulawulwayo ngokunethezeka kwendlela esetshenziswa kakhulu kunazo zonke yokubopha amathebulethi. I-Pharma Grade inikeza ukugeleza kwempushana okuhle, ukufana kokuqukethwe, nokucindezelwa, okuwenza afanelekele ukucindezelwa okuqondile.
| Isicelo se-Pharma Excipients | Pharma Grade HPMC | Umthamo |
| I-Bulk Laxative | 75K4000,75K100000 | 3-30% |
| Amakhilimu, amaGel | 60E4000,75K4000 | 1-5% |
| Ukulungiselela Ophthalmic | 60E4000 | 01.-0.5% |
| Eye Drop Amalungiselelo | 60E4000 | 0.1-0.5% |
| Umenzeli Omisiwe | 60E4000, 75K4000 | 1-2% |
| Ama-Antacids | 60E4000, 75K4000 | 1-2% |
| I-Tablet Binder | 60E5, 60E15 | 0.5-5% |
| Umhlangano Wet Granulation | 60E5, 60E15 | 2-6% |
| I-Tablet Coatings | 60E5, 60E15 | 0.5-5% |
| I-Matrix yokukhishwa elawulwayo | 75K100000,75K15000 | 20-55% |
Izici Nezinzuzo
- Ithuthukisa izici zokugeleza komkhiqizo
- Yehlisa izikhathi zokucubungula
- Amaphrofayili wokuqedwa afanayo, azinzile
- Ithuthukisa ukufana kokuqukethwe
- Yehlisa izindleko zokukhiqiza
- Igcina amandla okuqina ngemuva kwenqubo yokuhlangana kabili (i-roller compaction).
Ukupakisha
Ukupakisha okujwayelekile kungu-25kg/drum
I-20'FCL: amathani ayi-9 ane-palletized; 10 ton unpalleted.
I-40'FCL: amathani ayi-18 ane-palletized; 20 ton unpalletized.abide by the contract”, uvumelana nemfuneko yemakethe, ujoyina ngenkathi usemqhudelwaneni wemakethe ngekhwalithi yayo ephezulu kanye nokuhlinzeka ngosizo olubanzi kakhulu nolukhethekile kubathengi ukuze babavumele bathuthuke babe abawinile ababalulekile. Ukuphishekela enkampanini, kuzoba ukwaneliseka kwamakhasimende ukulethwa okusheshayo Ukugcinwa Kwamanzi Okuphezulu Ikhwalithi Ephakeme kanye Nokugcinwa Kwamanzi Okuphezulu kanye ne-High Viscos Isixazululo sizohlinzeka ngekhwalithi ephezulu ye-Viscos ye-HP. amabanga amanani ancintisanayo Qala ukuzuza ezinsizeni zethu eziphelele ngokusithinta namuhla.
Ukulethwa okusheshayoI-China Coating Auxiliary Agents kanye Nezinto Zokwakha, Ithini intengo enhle? Sinikeza amakhasimende ngentengo yefekthri. Esimweni sekhwalithi enhle, ukusebenza kahle kudinga ukunakwa futhi kugcinwe inzuzo efanele ephansi nenempilo. Kuyini ukulethwa okusheshayo? Senza ukulethwa ngokwezidingo zamakhasimende. Nakuba isikhathi sokulethwa sincike enanini le-oda nobunkimbinkimbi balo, sisazama ukuhlinzeka ngezinto ngesikhathi. Ngethemba ukuthi singaba nobudlelwano bebhizinisi besikhathi eside.
