I-Hydroxypropylm methylcellulose (HPMC) iyingxenye esetshenziswayo esetshenziswa kabanzi kwizimboni ezahlukahlukene ngenxa yokwakheka kwayo kwamakhemikhali okuyingqayizivele kanye nezakhiwo.
1. Ukwakheka kwamakhemikhali:
a. I-Cellulose Backbone:
I-HPMC i-cellulose derivative, okusho ukuthi isuselwa ku-cellulose, i-polysaccharide etholakala ezindongeni zezitshalo. I-Cellulose iqukethe amayunithi aphindaphindwayo we-β-d-glucose axhumeke nge-β (1 → 4) Bonds ama-glycosidic.
b. Indawo:
Ku-HPMC, i-Hydroxyl (-OH) Ukungabizi kwe-cellulose backbone kufakwa esikhundleni samaqembu we-methylypropylyl. Lokhu kufakazelwa kwenzeka ngokusabela kokuthezeka. Izinga lokufaka esikhundleni (DS) lisho inani elijwayelekile lamaqembu we-hydroxyl afakwe esikhundleni soyunithi ye-glucose ngayinye ku-cellulose chain. Amaqembu we-DS we-methyl kanye ne-hydroxypropyl ahlukile, okuthinta ukusebenza kwe-HPMC.
2. Synthesis:
a. Ukuqothuka:
I-HPMC ihlelwe ngokusabela kokuthenjwa kwe-cellulose nge-propelene oxide ne-methyl chloride. Le nqubo ifaka ukuphendula i-cellulose nge-propelene oxide ukwethula amaqembu we-hydroxypropys bese kuthi nge-methyl chloride ukwethula amaqembu we-methyl.
b. Degree of ehlukile yokulawula:
I-DS ye-HPMC ingalawulwa ngokulungisa imibandela yokuphendula efana nokushisa, isikhathi sokuphendula, kanye nokuhlushwa okusebenzayo.
3. Ukusebenza:
a. I-Solubity:
I-HPMC iyanyibilika emanzini kanye nezinye izixazululo ze-organic, njenge-methanol ne-ethanol. Kodwa-ke, i-solubility yayo incipha ngesisindo esikhulayo se-molecular kanye nezinga lokufaka esikhundleni.
b. Ukwakheka kwamafilimu:
I-HPMC yakha ifilimu esobala, evumelana nezimo lapho ichithwa emanzini. Lawa mafilimu anamandla amahle okwenziwa ngemishini kanye nezakhiwo ezinesithiyo.
C. I-Viscosity:
Izixazululo ze-HPMC zibonisa ukuziphatha kwe-Pseudoplastic, okusho ukuthi ukubonakala kwawo kuncipha ngezinga elikhulayo le-shear. I-viscosity yezixazululo ze-HPMC incike ezintweni ezifana nokuhlushwa, isisindo samangqamuzana, kanye nesilinganiso sokufakwa esikhundleni.
d. Ukugcinwa kwamanzi:
Enye yezinto ezibalulekile ze-HPMC yikhono layo lokugcina amanzi. Le mpahla ibalulekile kuzicelo ezahlukahlukene ezinjengezinto zokwakha, lapho i-HPMC isetshenziswa njenge-ejenti enkulu kanye ne-ejenti yokugcina amanzi.
e. Adhesion:
I-HPMC ivame ukusetshenziswa njenge-adhesive emikhakheni ehlukahlukene ngenxa yekhono layo lokwakha izibopho eziqinile ezingxenyeni ezihlukile.
4. Isicelo:
a. Imboni Yezemithi:
Emikhakheni, i-HPMC isetshenziswa njenge-binder, i-ejenti ye-film coating, i-ejenti yokukhishwa okulawulwayo, kanye ne-viscoosity modifier ekusungulweni kwethebhulethi.
b. Imboni Yokwakha:
I-HPMC yengezwa ku-masters esekwe ku-monce, ama-plasters asuselwa ku-gypsum kanye nokunamathela kwe-tile ukwenza ngcono ukusebenziseka, ukugcinwa kwamanzi nokunamathelisa.
C. Imboni yokudla:
Embonini yokudla, i-HPMC isetshenziswa njengesikhulu, i-stabilizer kanye ne-emulsifier emikhiqizweni efana nososo, ukugqoka kanye no-ayisikhilimu.
d. Imikhiqizo Yokunakekelwa Kwakho:
I-HPMC isetshenziswa njenge-swerener, emulsifier kanye ne-ejenti eyakha amafilimu emikhiqizweni yokunakekelwa komuntu siqu njenge-shampoos, ama-lotion kanye nokhilimu.
e. Amapende nezimbobo:
Ku-Paints kanye ne-Coatings, i-HPMC isetshenziselwa ukwenza ngcono ukuhlakazwa kwezithombe, ukulawulwa kwe-viscosity nokugcinwa kwamanzi.
I-Hydroxypropylmethylcelcelcellellellulose (HPMC) iyindawo ehlukahlukene enobubanzi bezinhlelo zokusebenza kuyo yonke imboni ehlukahlukene. Ukwakheka kwayo okuhlukile kwamakhemikhali, ukuhlanganiswa kanye nezakhiwo kukwenza kube isithako esibalulekile emikhakheni, izinto zokwakha, ukudla, imikhiqizo yokunakekelwa komuntu siqu kanye nopende / izigqoko. Ukuqonda izakhiwo ze-HPMC kuvumela izinhlelo zokusebenza ezenziwe ngezifiso emikhakheni ehlukene, kufaka isandla ekusetshenzisweni kwayo okusakazekile nokubaluleka kwezinqubo zanamuhla zokukhiqiza.
Isikhathi sePosi: Feb-22-2024