I-Hydroxypropyl methylcellulose (HPMC)iyi-ether ye-cellulose ebalulekile enezinhlobonhlobo zezicelo, ikakhulukazi emikhakheni yokwakha, imithi, ukudla, njll Ngokwezindlela ezahlukene zokucubungula, i-HPMC ingahlukaniswa ngezinhlobo ezilashwe phezulu nezingalashwa.
1. Umehluko ezinqubweni zokukhiqiza
I-HPMC Engelashiwe
I-HPMC engalashiwe ayitholi ukwelashwa okukhethekile kokumbozwa kwendawo ngesikhathi senqubo yokukhiqiza, ngakho-ke i-hydrophilicity yayo kanye nokuncibilika kugcinwa ngokuqondile. Lolu hlobo lwe-HPMC luvuvukala ngokushesha futhi luqala ukuncibilika ngemva kokuxhumana namanzi, okubonisa ukwanda okusheshayo kwe-viscosity.
I-HPMC ephethwe phezulu
I-HPMC ephethwe ngokuphezulu izoba nenqubo eyengeziwe yokuhlanganisa ngemva kokukhiqiza. Izinto ezivamile zokwelashwa kwendawo yi-acetic acid noma ezinye izinhlanganisela ezikhethekile. Ngalokhu kwelashwa, kuzokwakhiwa ifilimu ye-hydrophobic ebusweni bezinhlayiya ze-HPMC. Lokhu kwelashwa kubambezela inqubo yayo yokuqedwa, futhi ngokuvamile kuyadingeka ukwenza ukuqedwa kusebenze ngokunyakazisa okufanayo.
2. Umehluko ezicini zokuncibilika
Izici zokuqedwa ze-HPMC engelashiwe
I-HPMC engalashiwe izoqala ukuncibilika ngokushesha ngemva kokuxhumana namanzi, afanele izimo ezinezidingo eziphezulu zejubane lokuhlakazeka. Kodwa-ke, njengoba ukuhlakazeka okusheshayo kujwayele ukwenza ama-agglomerate, isivinini sokudla kanye nokufana okunyakazayo kudinga ukulawulwa ngokucophelela.
Izici zokuqedwa ze-HPMC ephathwe phezulu
Ukwembeswa okungaphezulu kwezinhlayiya ze-HPMC ezilashwe phezulu kuthatha isikhathi ukuncibilika noma ukucekela phansi, ngakho-ke isikhathi sokuhlakazeka siba side, ngokuvamile imizuzu embalwa ukuya ngaphezu kwemizuzu eyishumi. Lo mklamo ugwema ukwakheka kwama-agglomerates futhi ulungele ikakhulukazi izigcawu ezidinga ukunyakaziswa okukhulu okusheshayo noma ikhwalithi yamanzi eyinkimbinkimbi phakathi nenqubo yokwengeza.
3. Umehluko ezicini ze-viscosity
I-HPMC ephathwe ngobuso ngeke ikhulule i-viscosity ngokushesha ngaphambi kokuhlakazwa, kuyilapho i-HPMC engalashwa izokwandisa ngokushesha i-viscosity yesistimu. Ngakho-ke, ezimweni lapho i-viscosity idinga ukulungiswa kancane kancane noma inqubo idinga ukulawulwa, uhlobo oluphathwayo lunezinzuzo eziningi.
4. Umehluko ezimeni ezisebenzayo
I-HPMC engaphathwanga ngaphansi komhlaba
Ifanele izigcawu ezidinga ukuqedwa okusheshayo kanye nomthelela osheshayo, njengama-ejenti okugcoba ama-capsule osheshayo emkhakheni wezokwelapha noma ama-thickeners asheshayo embonini yokudla.
Isebenza kahle futhi kwezinye izifundo zaselabhorethri noma ukukhiqizwa kwezinga elincane ngokulawula okuqinile kokulandelana kokuphakelayo.
I-HPMC ephethwe phezulu
Isetshenziswa kabanzi embonini yezokwakha, isibonelo, odakeni olomile, i-adhesive tile, i-coatings neminye imikhiqizo. Kulula ukuyihlakaza futhi ayenzi ama-agglomerate, afaneleka kakhulu izimo zokwakha ezenziwe ngomshini.
Iphinde isetshenziswe kwamanye amalungiselelo emithi adinga ukukhululwa okuqhubekayo noma izithasiselo zokudla ezilawula izinga lokuqedwa.
5. Umehluko wamanani nesitoreji
Izindleko zokukhiqiza ze-HPMC eselashwe ngaphandle ziphakeme kancane kunaleyo engelashiwe, ebonakala emehlukweni wentengo yemakethe. Ukwengeza, uhlobo olulashwe phezulu lunembobo yokuzivikela futhi lunezidingo eziphansi zomswakama kanye nezinga lokushisa kwendawo yokugcina indawo, kuyilapho uhlobo olungalashwa lune-hygroscopic futhi ludinga izimo zokugcina eziqinile.
6. Isisekelo sokukhetha
Lapho ukhetha i-HPMC, abasebenzisi kudingeka bacabangele amaphuzu alandelayo ngokuya ngezidingo ezithile:
Ingabe izinga lokuqedwa libalulekile?
Izidingo zezinga lokukhula kwe-viscosity.
Ukuthi izindlela zokuphakela nezindlela zokuxuba zilula ukwenza ama-agglomerate.
Inqubo yezimboni yohlelo oluqondiwe kanye nezidingo zokugcina zokusebenza komkhiqizo.
Ukwelashwa okungaphezulu nokungaphathwanga ebusweniI-HPMCbabe nezici zabo. Owokuqala uthuthukisa ukusebenziseka kalula kanye nokuzinza kokusebenza ngokushintsha ukuziphatha kokuhlakazwa, futhi ulungele ukukhiqizwa kwezimboni ezinkulu; lesi sakamuva sigcina izinga eliphezulu lokuhlakazeka futhi ifaneleka kakhulu imboni yamakhemikhali amahle edinga izinga eliphezulu lokuhlakazeka. Ukukhetha ukuthi yiluphi uhlobo okufanele luhlanganiswe nesimo sesicelo esithile, izimo zenqubo kanye nesabelomali sezindleko.
Isikhathi sokuthumela: Nov-20-2024