I-HPMC vs HEC: 6 umehluko udinga ukwazi!

Yethula:

I-Hydroxypropylmethylcellellose (HPMC) neHydroxYethylcellulose (HEC) zombili zisetshenziswa izithasiselo ezivame ukusetshenziswa ekudleni, kwezimboni zokugcoba kanye nemithi. Lawa ma-cellulose derivativeveves anamathemba wohlelo lokusebenza abanzi ngenxa yokuqina kwamanzi ahlukile, ukuqina kokuqina, kanye nekhono elihle kakhulu lefilimu.

Isakhiwo se-1.Chical:

I-HPMC iyi-polymer yokwenziwa ethathwe ku-cellulose. Kwenziwa ngokushintsha kwamakhemikhali iselula yemvelo ngokungeza i-propelene oxide ne-methyl chloride. I-HEC futhi inguhlobo lwe-cellulose derivative, kepha yenziwa ngokuphendula iselula yemvelo nge-oxide ye-ethylene oxide bese uyiphatha nge-alkali.

2. I-Solubity:

Kokubili i-HPMC ne-HEC kuncibilika amanzi futhi kungancishiswa emanzini abandayo. Kepha i-solubility kaHec iphansi kune-HPMC. Lokhu kusho ukuthi i-HPMC inokuhlakazeka okungcono futhi ingasetshenziswa kalula ekwakhekeni.

3. I-Viscosity:

I-HPMC ne-HEC zinezici ezihlukile ze-viscosity ngenxa yezinhlaka zazo zamakhemikhali. I-HEC inesisindo esiphakeme se-molecular nesakhiwo se-denser kune-HPMC, okunikeza i-viscosity ephezulu. Ngakho-ke, i-HEC ivame ukusetshenziswa njengomuntu omkhulu ngokwakhiwa okudinga ukubonakala okuphezulu, ngenkathi i-HPMC isetshenziswa ekwakhiweni okudinga ukubonakala okuphansi.

4 Ukusebenza okwenziwe ngefilimu:

Zombili i-HPMC ne-HEC zinamakhono amahle kakhulu akha amafilimu. Kepha i-HPMC inokushisa okuphansi kwefilimu, okusho ukuthi kungasetshenziswa emazingeni okushisa aphansi. Lokhu kwenza i-HPMC ilungele ukusetshenziswa ekwakhiweni okudinga izikhathi zokumisa ngokushesha kanye nokunamathela okungcono.

5. Ukuqina:

I-HPMC ne-HEC zizinzile ngaphansi kwezimo eziningi ze-PH kanye nokushisa. Noma kunjalo, i-HEC izwela kakhulu izinguquko ze-PH kune-HPMC. Lokhu kusho ukuthi i-HEC kufanele isetshenziswe ekwakhiweni ngohlobo lwe-PH kuya ku-10, ngenkathi i-HPMC ingasetshenziswa ebangeni elibanzi le-PH.

6. Isicelo:

Izici ezihlukile ze-HPMC ne-HEC zizenza zilungele izinhlelo ezihlukile. I-HEC isetshenziswa kakhulu njenge-ejenti ekhuthele ekunikezelweni kwezimonyo kanye nezemithi. Iphinde isetshenziswe njenge-ejenti ye-binder ne-film-kwakha ukwakheka kwethebhulethi. I-HPMC isetshenziswa njengesikhudlwana, i-stabilizer, kanye ne-ejenti eyakha amafilimu ekudleni, izidakamizwa, kanye nokwakheka kwezimomozo. Iphinde isetshenziswe njenge-ejenti ye-gelling kwezinye izinhlelo zokusebenza zokudla.

Ekuphetheni:

I-HPMC ne-HEC yizo zombili izinto ze-cellulose enezindawo ezihlukile ezilungele izinhlelo ezihlukile. Ukuqonda umehluko phakathi kwalezi zithangezo ezimbili kungakusiza ukhethe okulungile ngeresiphi yakho. Sekukonke, i-HPMC ne-HEC kuyinto ephephile futhi esebenzayo enikeza izinzuzo eziningi ekudleni, izimboni zokugcoba kanye nemithi.