Hydroxypropyl methylcellulose phthalate(I-HPMCP) iyisisulu sokutholwa esiguquliwe esivame ukusetshenziswa embonini yezemithi. Isuselwa ku-hydroxypropyll methylcellulose (HPMC) ngokusebenzisa okunye ukuguqulwa kwamakhemikhali nge-phthalic anhydride. Lokhu kuguqulwa kudlulisela izakhiwo ezihlukile ku-polymer, okwenza kube lulungele izinhlelo ezithile ekwakhekeni kwezidakamizwa.

Nazi izici ezibalulekile kanye nokusetshenziswa kwe-hydroxypropyllylyll methylcellulose perthalate:

1. I-EnterIC Coating:
   • I-HPMCP isetshenziswa kabanzi njengezinto zokuhlangana ze-Enteric ze-DoSAge amafomu afana namathebulethi kanye nama-caplule.
   • I-EnterIC Coatings yenzelwe ukuvikela isidakamizwa kusuka kwimvelo ye-acid yesisu futhi yenza ukudedelwa kwemvelo ye-alkaline eyengeziwe yamathumbu amancane.
2. I-Solubity ethembele ebusuku:
   • Enye yezinto ezihlukile ze-HPMCP yi-solubity yayo ethembele e-Ph. Ihlala i-infoluble ezindaweni ezine-acidic (ph ngezansi kuka-5.5) futhi iba incibilika ezimeni ze-alkali (ph ezingezelwe 6.0).
   • Le mpahla ivumela ifomu le-dosage le-Exentric-camera elihlanganisiwe ukuze lidlule esiswini ngaphandle kokukhipha umuthi bese licibilika emathunjini ukumuncwa izidakamizwa.
3. Ukumelana nesisu:
   • I-HPMCP inikezela ukumelana esigangeni, ukuvikela umuthi ukuthi ungakhishwe esiswini lapho kungadilizwa khona noma kubangele ukucasuka.
4. Ukukhishwa okulawulwayo:
   • Ngaphezu kwe-Electic Coating, i-HPMCP isetshenziswa ekwakhiweni okulawulwa okulawulwayo, okuvumela ukukhishwa okubambezelekile noma okunwetshiwe komuthi.
5. Ukulupheka:
   • I-HPMCP ngokuvamile iyahambisana nohlu oluhlukahlukene lwezidakamizwa futhi lungasetshenziswa ezakhiweni ezahlukahlukene zemithi.

Kubalulekile ukuqaphela ukuthi ngenkathi i-HPMCP iyinto esetshenziswa kabanzi futhi esebenza ngempumelelo ye-Enteric Coating Coating, ukukhethwa kwe-Enteric Coatic kuncike ezintweni ezifana nephrofayili ethile yezidakamizwa, efiselekayo, kanye nezidingo zesiguli. Amakhemikhali kufanele acabangele izakhiwo ze-physichicochemical zomuthi kanye nezinto zokuhlanganisa ze-Enteric zokufeza umphumela owuthandayo wezokwelapha.

Njenganoma ikuphi ukuthambekela kwemithi, kufanele kulandelwe izindinganiso nemihlahlandlela yokulawula ukuze kuqinisekiswe ukuphepha, ukusebenza ngempumelelo kanye nekhwalithi yomkhiqizo wokugcina wezemithi. Uma unemibuzo ethile mayelana nokusetshenziswa kwe-HPMCP kumongo othile, kunconywa ukubonisana nemihlahlandlela efanelekile yemithi noma iziphathimandla ezilawulayo.