I-Hydroxyproppropyllocyslosel ephansi

I-Hydroxyproppropyllopyllopyllopyllopyllopylls ephansi (L-HPC) etholwa yi-cellulose, i-polymer yemvelo etholakala ezindongeni zeseli zezitshalo. I-L-HPC ishintshiwe ukuthuthukisa i-solubility yayo nezinye izakhiwo, okwenza kube yinto eguquguqukayo enezicelo eziningi ezitsheni zemithi, ukudla, kanye nezimboni zezimonyo.

I-hydroxyproppropcellellose ephansi ephansi (L-HPC) etholakala esikhundleni esisezingeni eliphansi elishintshiwe eliguqulwe ngokuyinhloko ukuthuthukisa i-solubity yalo emanzini namanye ama-solvents. I-cellulose iyi-polysaccharide eqondile ehlanganiswe ama-glucose amayunithi anala ngokwemvelo futhi yingxenye yesakhiwo sezindonga zeseli zezitshalo. I-L-HPC ihlelwe ngamakhemikhali ukuguqula i-cellulose, yethula amaqembu ama-hydroxypropyl ukuthuthukisa i-solubility yayo ngenkathi egcina ezinye zezakhiwo ezifiselekayo zeselula.

Ukwakheka kwamakhemikhali kwe-hydroxypropproses ephansi ephansi

Isakhiwo samakhemikhali se-L-HPC siqukethe i-cellulose backbone neqembu le-hydroxypropyl elinamathele kwi-hydroxyl (oh) iqembu leyunithi le-glucose. Izinga lokufaka esikhundleni (DS) lisho inani eliphakathi lamaqembu we-hydroxypropyl ngamunye uphiko lwe-glucose eCellulose Chain. Ku-L-HPC, i-DS ihlotshaniswa ngamabomu ukuze ilinganise i-soubity ethuthukisiwe ngokugcina izakhiwo ezingaphakathi kwe-cellulose.

Ukuhlanganiswa kwe-hydroxyprosesprose ephansi ephansi

Ukuhlanganiswa kwe-L-HPC kubandakanya ukusabela kwe-cellulose ene-propelene oxide phambi kwe-alkaline catalyst. Lokhu kuphendula kuphumela ekungenisweni kwamaqembu ama-hydroxypropyl kumaketanga we-cellulose. Ukulawulwa ngokucophelela kwezimo zokuphendula, kufaka phakathi izinga lokushisa, isikhathi sokuphendula, kanye nokuhlushwa kwe-catalyst, kubalulekile ukufeza izinga olufunayo lokufaka esikhundleni.

Izici ezithinta i-soubity

1. Izinga lokufaka esikhundleni (DS):

I-solubity ye-L-HPC ithintwa yi-DS yayo. Njengoba i-DS inyuka, i-hydrophicity yeqembu le-hydroxypropyl liba isithunywa ngokwengeziwe, ngaleyo ndlela lithuthukise i-solubity emanzini nasezindaweni ezinamakhaza.

2. Isisindo samangqamuzana:

Isisindo se-molecular se-L-HPC kungenye into ebucayi. Isisindo esiphakeme se-molecular L-HPC singakhombisa ukuncipha kwe-solubity ngenxa yokusebenzisana okwenziwe nge-intermolecular kanye nokufakwa kokena.

3. Ukushisa:

I-Solubity ngokuvamile inyuka ngamazinga okushisa ngoba amazinga okushisa aphezulu ahlinzeka amandla amaningi ukuphula amabutho we-intermolecular futhi ukhuthaze ukusebenzisana kwe-polymer-solvent.

4 Inani le-PH yesisombululo:

Ikhambi lekhambi lithinta i-ionization yamaqembu e-hydroxypropyl. Kwezinye izimo, ukulungisa i-PH kungakhuphula i-solubity ye-L-HPC.

5. Uhlobo lwe-solvent:

I-L-HPC ikhombisa i-soubity enhle emanzini kanye nama-sol sol sols ahlukahlukene. Ukukhethwa kwe-solvent kuncike kwisicelo esithile kanye nezakhiwo ezifiselekayo zomkhiqizo wokugcina.

Ukusetshenziswa kwe-hydroxyproproses ephansi ephansi

1. Izidakamizwa:

I-L-HPC isetshenziswa kabanzi embonini yezemithi njenge-binder, ukuqhelelana ne-ejenti yokukhishwa kwe-tablet ngokwakhiwa kwethebulethi. I-solubility yayo ku-fluids asesiswini yenza ilungele izinhlelo zokusebenza zokulethwa kwezidakamizwa.

2. Imboni yokudla:

Embonini yokudla, i-L-HPC isetshenziswa njenge-smighter kanye ne-stabilizer emikhiqizweni ehlukahlukene. Amandla awo okwenza ijeli elicacile ngaphandle kokuthinta ukunambitheka noma umbala wemikhiqizo yokudla kwenza kube yigugu ekwakhiweni kokudla.

3. I-COSMETICS:

I-L-HPC isetshenziswa ekwakhekeni kwezimonyo zezakhiwo zayo ezakhayo zefilimu nezikhuthazayo. Kuyasiza ukuthuthukisa ukuqina kanye nokuthungwa kwezimonyo ezifana nokhilimu, ama-lotion nama-gels.

4. I-coating application:

I-L-HPC ingasetshenziswa njengezinto zokuhlanganisa amafilimu ezimbonini zezemithi nezokudla ukuhlinzeka ngesendlalelo sokuvikela amaphilisi noma imikhiqizo ye-confectionery.

I-hydroxypropypropypropyllopys ephansi ephansi iyi-polymer esebenzayo nge-solubelity ethuthukisiwe ethathwe ku-cellubelose yemvelo etholakala ezitshalweni. Izakhiwo zayo ezihlukile zikwenza zibalulekile kwizimboni ezahlukahlukene kufaka phakathi ama-Pharmaceuticals, ukudla nezimonyo. Ukuqonda izici ezithonya i-solubity yayo kubalulekile ukwenza kahle ukusetshenziswa kwayo kuzicelo ezihlukile. Njengoba ukucwaninga kwe-polymer Science kanye nentuthuko kuyaqhubeka, i-L-HPC kanye nezinto ezifanayo ze-cellulose zithola izinhlelo ezintsha nezintsha ekwakhiweni kwezinkambu.