Ukuphepha kwe-HPMC ezithasiselweni zokudla

1. Uhlolojikelele lwe-HPMC

I-HPMC (Hydroxypropyl Methylcellulose) iphuma ku-cellulose etholakala ngokuguqulwa kwamakhemikhali. Itholakala ku-cellulose yezitshalo zemvelo ngokusebenzisa ukusabela kwamakhemikhali njenge-methylation ne-hydroxypropylation. I-HPMC inokuncibilika okuhle kwamanzi, ukulungiswa kwe-viscosity, izakhiwo zefilimu nokuzinza, ngakho-ke isetshenziswe kabanzi ezimbonini eziningi, ikakhulukazi emkhakheni wokudla, imithi kanye nezimonyo, njenge-thickener, stabilizer, emulsifier kanye ne-gelling agent.

Embonini yokudla, i-HPMC ivame ukusetshenziswa njenge-thickener, i-ejenti ye-gelling, i-humectant, i-emulsifier kanye ne-stabilizer. Ukusetshenziswa kwayo okuhlukahlukene ekudleni kuhlanganisa: isinkwa, amakhekhe, amabhisikidi, uswidi, u-ayisikhilimu, izinongo, iziphuzo nokunye ukudla okunempilo. Isizathu esibalulekile sokusetshenziswa kwayo okubanzi ukuthi i-AnxinCel®HPMC inokusimama okuhle kwamakhemikhali, akulula ukusabela ngayo nezinye izithako, futhi yonakaliswa kalula ngaphansi kwezimo ezifanele.

2. Ukuhlolwa kokuphepha kwe-HPMC

I-HPMC iye yaqashelwa futhi yagunyazwa yizikhungo eziningi ezilawula ukuphepha kokudla zikazwelonke nezamazwe ngamazwe njengesengezo sokudla. Ukuphepha kwayo kuhlolwa ngokuyinhloko ngalezi zici ezilandelayo:

Ucwaningo lwe-Toxicology

Njengokuphuma ku-cellulose, i-HPMC isekelwe ku-cellulose yezitshalo futhi inobuthi obuphansi uma kuqhathaniswa. Ngokwezifundo eziningi ze-toxicology, ukusetshenziswa kwe-HPMC ekudleni akubonisi ubuthi obusobala noma obungapheli. Ucwaningo oluningi lubonise ukuthi i-HPMC inokuvumelana okuhle kwe-biocompatibility futhi ngeke ibangele imiphumela esobala enobuthi emzimbeni womuntu. Isibonelo, imiphumela yokuhlolwa okubukhali kobuthi bomlomo be-HPMC kumagundane ibonise ukuthi akukho ukusabela okusobala okunobuthi okwenzeka ngemithamo ephezulu (edlula ukusetshenziswa kwansuku zonke kwezithasiselo zokudla).

I-Intake kanye nama-ADI (Ukudla Kwansuku zonke Kwamukelekile)

Ngokokuhlolwa kochwepheshe bokuphepha kokudla, ukudla okwamukelekayo (ADI) kwansuku zonke kwe-HPMC ngeke kulimaza impilo yomuntu phakathi kwebanga elifanele lokusetshenziswa. I-International Expert Committee on Food Additives (JECFA) kanye ne-US Food and Drug Administration (FDA) kanye nezinye izikhungo zibone ukuphepha kwe-HPMC njengesengezo sokudla futhi bakubekela imikhawulo ephusile yokusebenzisa. Embikweni wayo wokuhlola, i-JECFA iveze ukuthi i-HPMC ayizange ibonise noma yimiphi imiphumela enobuthi esobala, futhi ukusetshenziswa kwayo ekudleni ngokuvamile kungaphansi kakhulu kwenani le-ADI elimisiwe, ngakho abathengi akudingeki bakhathazeke ngezingozi zayo zezempilo ezingase zibe khona.

Ukungezwani komzimba kanye nokusabela okungekuhle

Njengento yemvelo, i-HPMC inezigameko eziphansi zokungezwani komzimba. Abantu abaningi abanakho ukungezwani komzimba ne-HPMC. Kodwa-ke, abanye abantu abazwelayo bangase babe nezimpawu zokungezwani kahle nezincane njengokuqubuka nokuphelelwa umoya lapho bedla ukudla okuqukethe i-HPMC. Ukusabela okunjalo kuvame ukungavamile. Uma ukungakhululeki kwenzeka, kutuswa ukuba uyeke ukudla ukudla okuqukethe i-HPMC futhi ufune iseluleko sikadokotela ochwepheshe.

Ukusetshenziswa isikhathi eside kanye nempilo yamathumbu

Njengenhlanganisela yamangqamuzana amaningi, i-AnxinCel®HPMC inzima ukumuncwa umzimba womuntu, kodwa ingadlala indima ethile njengefayibha yokudla emathunjini futhi ikhuthaze i-peristalsis yamathumbu. Ngakho-ke, ukudla okusesilinganisweni kwe-HPMC kungase kube nomthelela othile omuhle empilweni yamathumbu. Isibonelo, ezinye izifundo zibonise ukuthi i-HPMC inamandla athile okuthuthukisa i-peristalsis yamathumbu kanye nokukhulula ukuqunjelwa. Kodwa-ke, ukuphuza ngokweqile kwe-HPMC kungase kubangele ukungakhululeki kwamathumbu, ukuphazamiseka kwesisu, isifo sohudo nezinye izimpawu, ngakho-ke isimiso sokulinganisela kufanele silandelwe.

3. Isimo sokuvunyelwa kwe-HPMC emazweni ahlukene

China

E-China, i-HPMC isohlwini njengesengezo sokudla esivunyelwe, ikakhulukazi esisetshenziswa kumaswidi, izinongo, iziphuzo, imikhiqizo ye-pasta, njll. Ngokusho "Okujwayelekile Kokusetshenziswa Kwezithako Zokudla" (GB 2760-2014), i-HPMC ivunyelwe ukusetshenziswa. ekudleni okukhethekile futhi kunemikhawulo eqinile yokusebenzisa.

iyuniyani yase-Europe

E-European Union, i-HPMC yaziwa futhi njengesengezo sokudla esiphephile, esinenombolo E464. Ngokombiko wokuhlola we-European Food Safety Authority (EFSA), i-HPMC iphephile ngaphansi kwezimo ezithile zokusetshenziswa futhi ayibonisi imiphumela emibi empilweni yomuntu.

I-united states

I-US FDA ibala i-HPMC njengento “Eyaziwa Ngokujwayelekile Njengephephile” (GRAS) futhi ivumela ukusetshenziswa kwayo ekudleni. I-FDA ayibeki imikhawulo eqinile yomthamo wokusetshenziswa kwe-HPMC, futhi ihlola ikakhulukazi ukuphepha kwayo ngokusekelwe kudatha yesayensi ekusebenziseni kwangempela.

Njengesengezo sokudla,I-HPMC ivunyelwe emazweni amaningi nasezifundeni emhlabeni jikelele futhi ibhekwa njengephephile ngaphakathi kwebanga lokusetshenziswa elishiwo. Ukuphepha kwayo kuqinisekiswe izifundo eziningi ezinobuthi kanye nezinqubo zomtholampilo, futhi akubangeli umonakalo omkhulu empilweni yomuntu. Kodwa-ke, njengazo zonke izithasiselo zokudla, ukuthathwa kwe-HPMC kufanele kulandele umgomo wokusetshenziswa okunengqondo futhi kugweme ukudla ngokweqile. Abantu abane-allergies kufanele baqaphe lapho bedla ukudla okuqukethe i-HPMC ukuze banciphise ukuvela kokusabela okungekuhle.

I-HPMC iyisengezo esisetshenziswa kakhulu nesiphephile embonini yokudla, ebeka engcupheni encane empilweni yomphakathi. Ngokuthuthuka kwesayensi nobuchwepheshe, ucwaningo nokugadwa kwe-AnxinCel®HPMC kungase kuqine ngokuzayo ukuze kuqinisekiswe ukuphepha kwayo.