Iqhaza le-HPMC ekushintsheni izakhiwo ze-bhe ngokomqondo zokumiswa

I-OcudRection:

I-Hydroxypropyl Methylcellulose (HPMC) iyinhlangano eguquguqukayo esetshenziswa kabanzi kwizimboni ezahlukahlukene, kubandakanya nemithi, ukwakhiwa nokudla. Enye yezicelo zayo ezibalulekile ekushintsheni izakhiwo ze-bhe ngokomqondo zokumiswa. I-RHEOLOGY, ukucwaninga kokugeleza kanye nokwenza izinto zokwakha, kubalulekile ekuqondeni nasekulambeni indlela yokuziphatha kokumihlela.

Ukuguqulwa kwe-2.Viscuscur:

I-HPMC yaziwa ngekhono layo lokuguqula i-viscosing yokumiswa. Njenge-hydrophilic polymer, idonsa kalula amanzi futhi yakha isakhiwo esinjengegugu. Uma kungezwe ekumisweni, i-HPMC Molecule Hydrate kanye ne-Entangle, ukukhulisa ukubonakala kohlelo. Ubungako bokuguqulwa kwe-viscosity kuncike ezintweni ezinjengokwehlulwa kwe-HPMC, isisindo samangqamuzana, kanye nesilinganiso sokufaka esikhundleni. Ukugxila okuphezulu kanye nezinsimbi zamangqamuzana ze-HPMC ngokuvamile ziholela ekuthuthukisweni okukhulu kwe-viscosity.

Ukuziphatha okushibilika:

Ngaphezu kokuguqula i-viscosity, i-HPMC ingathonya ukusebenza okunciphisayo kokukhunjulwa. I-Shear-Thwerning isho ukwehla okubonakalayo okubonakalayo ngaphansi kwengcindezi ye-shear esetshenzisiwe, okuvame ukubonwa ezinhlelweni eziningi zokumiswa. Ukuba khona kwe-HPMC kuguqula inkomba yokuziphatha yokugeleza kokumiswa, okuholela kwizakhiwo ezithuthukisayo ezithuthukisiwe. Le mpahla inenzuzo ikakhulukazi kuzinhlelo zokusebenza lapho kufiswa khona ukuhanjiswa okulula noma ukusabalalisa, njengakumakhemikhali emithi noma imikhiqizo yokudla.

Ukuqina kwe-4.Spension:

Enye into ebalulekile ye-Rheology ukuqina kokumiswa, okubhekisele emandleni ezinhlangano ukuthi zihlale zihlakazekile futhi zimelane nokudideka ngokuhamba kwesikhathi. I-HPMC idlala indima ebalulekile ekuthuthukiseni ukuqina kokumiswa kwezindlela eziningana. Okokuqala, umphumela wayo wokuqina usiza ekuvikeleni izinhlayiyana ezixazululwa ngokwandisa ukuvulwa kwesigaba esiqhubekayo. Okwesibili, i-HPMC yakha isithiyo esivikelekile esizungeze izinhlayiya, ukunciphisa ukusebenzisana kokuxhumana kanye nokuhlanganiswa. Lesi simo sokuqina kwezikhuthazi sisiza ukugcina i-homogeneity yokumiswa.

I-5.influence yezakhiwo ze-HPMC:

Umthelela we-bhedo we-HPMC ngokumiswa uthonywa yizakhiwo ezimbalwa ezibalulekile ze-polymer. Isisindo se-molecular sithinta ubukhulu bokufakwa kwe-chain futhi, ngenxa yalokho, ukuthuthukiswa kwe-viscosity. Isisindo esiphakeme se-molecular HPMC sivame ukuletha ukubonakala okukhulu kokukhunjulwa. I-degree yokufaka esikhundleni (DS), esisho inani le-hydroxypropyll kanye namaqembu we-methoxy ngophiko lwe-glucose, futhi lithonya ukusebenza kwe-rheological. Amanani aphezulu we-DS avela kuma-hydration anamandla kanye nokwakheka kwe-gel enkulu, okuholela ekutheni kwenyuke ngokubonakalayo.

Izicelo ze-6.Practical:

Izakhiwo ze-Rheological zokumiswa kokumiswa okuguqulwe nge-HPMC thola izinhlelo ezisakazekile ezigcwele kuyo yonke imboni ehlukahlukene. Emakhishini emithi, i-HPMC isetshenziswa njenge-ejenti yokumisa ukuqinisekisa ukusatshalaliswa okufanayo kwezinhlayiya zezidakamizwa futhi kuthuthukise ukuqina. Ezintweni zokwakha ezinjenge-cemential mars kanye nama-grouts, i-hpmc ithuthukisa umsebenzi, ukunamathela, kanye nokumelana kwe-sag. Ngokufanayo, emikhiqizweni yokudla efana namasoso, ukugqoka, nemikhiqizo yobisi, i-HPMC yenza ukugcwala, ukuqina, kanye nomlomo.

I-Hydroxypropyl Methylcellulose (HPMC) yi-polymer esebenzayo ethonya kakhulu izakhiwo ze-Rheological zokumiswa. Amandla alo okuguqula indlela yokubonana, yenza ngcono ukusebenza okunciphise ukuncipha, futhi kuthuthukiswe ukuqina kokumiswa kwenza kube yisengezo esibalulekile ezimbonini ezahlukahlukene. Ngokuqonda izindlela lapho i-HPMC ixhumana ngokumiswa, abacwaningi namakhemikhali bangavumelanisa ukusetshenziswa kwayo ukuze bazuze izici ze-rheological ezifiselekayo ezinhlobonhlobo zezicelo.