I-Hydroxypropyl methylcellulose (HPMC) iyi-ether engeyona i-ionic encibilika emanzini e-cellulose esetshenziswa kabanzi ekwakhiweni, kwezokwelapha, ekudleni, kwezimboni zezimonyo nezimboni zamakhemikhali. Izici ze-viscosity zesisombululo sayo se-aqueous yizici ezibalulekile ezithinta ukusebenza kwayo kwesicelo.
1. Izici eziyisisekelo ze-HPMC
I-AnxinCel®HPMC iphuma ku-cellulose ehlanganiswe ngokwethula i-hydroxypropyl kanye namaqembu e-methyl ochungechungeni lwamangqamuzana e-cellulose. Ine-solubility enhle yamanzi kanye ne-viscosity ephakeme kakhulu, futhi ivame ukusetshenziselwa ukulungisa izixazululo ezinamanzi ngezakhiwo ezithile ze-rheological. Lezi zici zenza i-HPMC isetshenziswe kabanzi kuma-coatings, ama-adhesives, ukukhululwa okuqhubekayo kwezidakamizwa, izithasiselo zokudla nezinye izimboni.
2. Izici ze-viscosity zesisombululo samanzi se-HPMC
Izici ze-viscosity zesisombululo samanzi se-HPMC zithintwa izici eziningi, ikakhulukazi ezihlanganisa ukugxila, izinga lokushisa, izinga lokugunda, inani le-pH kanye nesakhiwo samangqamuzana.
Umphumela wokugxila ku-viscosity
I-viscosity yesisombululo samanzi se-HPMC iyanda ngokugxila okukhulayo. Lapho ukuhlushwa kwe-HPMC kuphansi, isisombululo samanzi sincane futhi sine-viscosity ephansi; njengoba ukuhlushwa kwanda, ukusebenzisana phakathi kwama-molecule kuyanda, futhi i-viscosity yesisombululo se-aqueous ikhula kakhulu. Ngokuvamile, i-viscosity yesisombululo se-HPMC ihlobene ngokuphawulekayo nokugxila kwayo, kodwa ijwayele ukuzinza ekugxilweni okuthile, okubonisa izici ze-viscosity zesixazululo.
Umthelela wezinga lokushisa ku-viscosity
Izinga lokushisa liyisici esibalulekile esithinta i-viscosity yesisombululo samanzi se-AnxinCel®HPMC. Njengoba izinga lokushisa likhuphuka, izibopho ze-hydrogen nokusebenzisana kwe-hydrophobic kuma-molecule e-HPMC kuzoba buthaka, okuholela ekwehleni kwamandla okubopha phakathi kwama-molecule, ngaleyo ndlela kunciphise i-viscosity yesisombululo esinamanzi. Ngokuvamile, i-viscosity yesisombululo samanzi se-HPMC sibonisa ukuthambekela okuphawulekayo kokwehla okunokushisa okukhulayo, ikakhulukazi ebangeni lokushisa eliphezulu. Lesi sici senza i-HPMC ibe nekhono elingcono lokulawula kwezinye izinhlelo zokusebenza zokulawula izinga lokushisa.
Umthelela we-shear rate ku-viscosity
Isixazululo samanzi se-HPMC sibonisa izici ezijwayelekile zoketshezi lwe-Newtonian ngamanani aphansi e-shear, okungukuthi, i-viscosity izinzile; kodwa-ke, ngamanani aphezulu wokugunda, i-viscosity yesisombululo se-HPMC izokwehla kakhulu, okubonisa ukuthi inezindawo zokugunda i-shear. Ama-molecule e-HPMC anezici ezithile ze-rheological. Ngamazinga aphansi e-shear, amaketanga e-molecular aphikisiwe kakhulu, enza ukumelana kwesakhiwo okuphezulu, okubonakaliswa njenge-viscosity ephakeme; emazingeni aphezulu e-shear, amaketanga e-molecular athambekele ukwelula, i-fluidity iyathuthukiswa, futhi i-viscosity iyancipha.
Umthelela wevelu ye-pH ku-viscosity
Isixazululo samanzi se-HPMC ngokuvamile sigcina i-viscosity ezinzile ngaphansi kokungathathi hlangothi kwezimo ezibuthakathaka ze-alkaline. Endaweni eqinile ye-asidi noma eyisisekelo eqinile, ama-molecule e-HPMC angase abhekane ne-protonation noma ukusabela kwe-deprotonation, okuholela ekushintsheni kwe-hydrophilicity, i-hydrophobicity kanye nokusebenzisana kwe-intermolecular phakathi kwama-molecule, ngaleyo ndlela kuthinte i-viscosity yesisombululo se-aqueous. Ngaphansi kwezimo ezijwayelekile, izinguquko ku-pH zinomthelela omncane ku-viscosity yezixazululo ze-HPMC, kodwa ngaphansi kwezimo ezibucayi ze-pH, ukuguqulwa kwe-viscosity kungase kubonakale kakhudlwana.
Umthelela wesakhiwo samangqamuzana ku-viscosity
Izici ze-viscosity ze-HPMC zihlobene eduze nesakhiwo sayo samangqamuzana. Izinga lokufakwa esikhundleni samaqembu e-hydroxypropyl kanye ne-methyl ku-molecule inomphumela obalulekile ku-viscosity yesisombululo esinamanzi. Ukuphakama kwezinga lokushintshwa kweqembu, kuqina i-hydrophilicity ye-HPMC kanye nokukhuphuka kwe-viscosity yesixazululo. Ngaphezu kwalokho, isisindo samangqamuzana e-HPMC siphinde sibe yisici esibalulekile esithinta i-viscosity yayo. Isisindo samangqamuzana sikhulu, iketango lamangqamuzana lide, futhi kuqina ukuxhumana phakathi kwama-molecule, okuholela ekuboneni okuphezulu kwesisombululo esinamanzi.
3. Ukubaluleka kwezici ze-viscosity zesisombululo samanzi se-HPMC ekusetshenzisweni
Izici ze-viscosity zesisombululo samanzi se-HPMC zibalulekile ekusebenziseni kwayo emikhakheni ehlukahlukene.
Inkambu yokwakha: I-HPMC ivame ukusetshenziswa odakeni lukasimende nezinto ezinamathelayo, futhi inemisebenzi yokujiya, ukugcina umswakama, nokwenza ngcono ukusebenza kokwakha. Izici zayo ze-viscosity zithinta ngqo ukusebenza nokunamathela kodaka. Ngokulungisa ukuhlushwa kanye nesakhiwo samangqamuzana e-HPMC, izakhiwo ze-rheological zodaka zingalawulwa, ngaleyo ndlela kuthuthukiswe kalula ukwakhiwa.
Imboni yezokwelapha: Isixazululo samanzi se-AnxinCel®HPMC sivame ukusetshenziswa ekulungiseni njengama-ejenti akhipha izidakamizwa, amagobolondo amaphilisi, namaconsi esweni. Izici zayo ze-viscosity zingathinta izinga lokukhululwa kwezidakamizwa futhi zilawule inqubo yokukhululwa kwezidakamizwa emzimbeni. Ngokukhetha i-HPMC enesisindo sengqamuzana esifanele kanye nezinga lokushintsha, izici zokukhishwa kwezidakamizwa zingalungiswa ukuze kuzuzwe imiphumela yokwelapha enembile.
Imboni yokudla: I-HPMC isetshenziswa njenge-thickener, stabilizer, kanye ne-emulsifier ekucubunguleni ukudla. Izici ze-viscosity zesisombululo saso samanzi zithinta ukunambitheka nokuzinza kokudla. Ngokulungisa uhlobo nenani le-HPMC esetshenzisiwe, ukuthungwa kokudla kungalawulwa ngokunembile.
Imboni yezimonyo: I-HPMC, njenge-thickener kanye ne-stabilizer kuzimonyo, ingathuthukisa ukuthungwa komkhiqizo, iwunikeze uketshezi olufanele kanye nomuzwa omuhle. Izici zayo ze-viscosity zinomthelela obalulekile kulwazi lomsebenzisi lwemikhiqizo efana nokhilimu, amajeli, nama-shampoos.
Izici ze-viscosity zeI-HPMC izixazululo ezinamanzi zithintwa yizici eziningi ezifana nokugxila, izinga lokushisa, izinga le-shear, inani le-pH, kanye nesakhiwo samangqamuzana. Ngokulungisa lezi zici, ukusebenza kwesicelo se-HPMC kungenziwa elungiselelwe ukuze kuhlangatshezwane nezidingo zezimboni ezahlukene zezakhiwo zayo ze-rheological. Ucwaningo olunzulu mayelana nezici ze-viscosity ze-HPMC izixazululo ezinamanzi azisizi nje kuphela ukuqonda izici zayo eziyisisekelo, kodwa futhi inikeza isiqondiso sethiyori ngokusetshenziswa kwayo ekukhiqizeni kwangempela.
Isikhathi sokuthumela: Jan-16-2025