Uyini umehluko phakathi kwe-carbomer ne-hydroxyyethylcellulose?

I-Carbomer ne-HydroxyEtylcellose (HEC) zombili izithako ezisetshenziswayo ezimbonini ezahlukahlukene, ikakhulukazi ezimotweni, emikhakheni kanye nemikhiqizo yokunakekelwa komuntu. Naphezu kwezicelo zazo ezifanayo njengabagibeli bokuqina kanye nabazinzayo, banezingoma ezihlukile zamakhemikhali, izakhiwo nezinhlelo zokusebenza.

1. Ukwakheka kwamakhemikhali:

I-Carbomer: Izimoto ze-carbomers zingama-polymers aphezulu wesisindo se-acrylic acrymers exhunywe nge-polyalkenyl ether noma i-divinyl glycol. Zivame ukukhiqizwa ngokuphendula kwe-polymerization.

I-HydroxyEtylcellosi: Ngakolunye uhlangothi, i-HydroxyEtylcellosise, ngakolunye uhlangothi, i-polymer etholakala ngokwemvelo. Kukhiqizwa ngokwelapha iselula nge-sodium hydroxide ne-ethylene oxide ukwethula amaqembu we-hydroxyethyl e-cellulose backbone.

2. Isakhiwo samangqamuzana:

I-Carbomer: Izimoto ze-carbomers zinesakhiwo esinama-molecular ane-molecular ngenxa yemvelo yazo exhumeke. Leli gabhu linomthelela emandleni alo okwenza inethiwekhi enezici ezintathu lapho i-hydrate, iholela ekutheni i-gelling kanye nezakhiwo ezilimele.

I-HydroxYethylcellose: I-HydroxyEthylcellose igcina ukwakheka okuqondile kwe-cellulose, amaqembu ama-hydroxyethyl anamathiselwe kuma-glucose amayunithi eceleni kwe-polymer chain. Lo mklamo olayini uthonya ukusebenza kwayo njengomuntu omkhulu kanye ne-stabilizer.

3. I-Solubity:

I-Carbomer: I-Carbomers imvamisa ihlinzekwa ngefomu elinempuphu futhi liyafakwa emanzini. Kodwa-ke, bangavuvukala bese benza hydrate ezixazululweni zamanzi, bakha ama-gels asobala noma ukusabalalisa okubonakalayo.

IHydroxYethylcellose: I-HydroxyEthylcellose nayo ihlinzekwa ngefomu elinempuphu kepha ilulaza kalula emanzini. Incibilikisa ukwakha izixazululo ezicacile noma ezithambile zeTurbid, kuya ngokugxila nezinye izinto zokwakha.

4. Ukuqina Kwezakhiwo:

I-Carbomer: Ama-Carbomers asebenza kahle kakhulu futhi angadala i-viscosity ekwakhekeni okuhlukahlukene, kufaka phakathi okhilimu, ama-gels kanye ne-lotions. Bahlinzeka ngezakhiwo ezinhle kakhulu zokumisa futhi zivame ukusetshenziswa ukuqinisa ama-emulsions.

IHydroxYethylcellose: I-HydroxyYethylcellose ibuye isebenze njengoMkhulu kepha ibonisa isimilo esihlukile se-rhelogical ngokuqhathaniswa nama-carbomers. Inika i-Pseudoplastic noma i-Shear-incishile ukugeleza ekwakhekeni, okusho ukuthi i-visa yayo yehla ngaphansi kwengcindezi ye-shear, lula uhlelo lokusebenza olulula nokusakazeka.

5. Ukuvumelana:

I-Carbomer: ama-carbomers ahambelana nezinhlobonhlobo zezithako zezimonyo namazinga we-PH. Kodwa-ke, bangadinga ukungathathi hlangothi nge-alkalis (isib.

I-HydroxyEtylcellosi: I-HydroxyEthylcellose iyahambisana ne-solvents ehlukahlukene kanye nezithako ezijwayelekile zezimonyo. Kuzinzile ngebanga elibanzi le-PH futhi akudingi ukungathathi hlangothi kokuqina.

6. Izindawo zohlelo lokusebenza:

I-Carbomer: I-Carbomers ithola ukusetshenziswa okubanzi emikhiqizweni yokunakekelwa komuntu siqu njengama-ayisikhilimu, ama-lotion, ama-gels, kanye nokwakhiwa kokunakekelwa kwezinwele. Zisetshenziswa futhi emikhiqizweni yezemithi njengamagceke e-topical kanye nezixazululo ze-ophthalmic.

IHydroxYethylcellose: I-HydroxyEthylcellose ivame ukuqashwa ekuhlinzekweni kwezimonyo kanye nokunakekelwa komuntu siqu, kufaka phakathi ama-shampoos, i-conditioners, ukuhlanza komzimba, kanye namazinyo. Iphinde isetshenziswe ezisetshenzisweni zezemithi, ikakhulukazi ezakhiweni eziphezulu.

7. Izici zemizwa:

I-Carbomer: I-Carbomer Greel Ngokuvamile ibonisa ukuthungwa okubushelelezi nokukhokhisa, okudlulisela isipiliyoni sezinzwa esifiselekayo ekwakhekeni. Kodwa-ke, bangase bazizwe benama-tacky kancane noma banamathele ohlelweni kwezinye izimo.

I-HydroxYethylcellose: I-HydroxyYethylcellulose ifaka umuvimbo futhi ongeyena onamathelayo. Ukuziphatha kwayo okunciphisayo kunomthelela ekusakazweni okulula kanye nokumuncwa, ukuthuthukisa ulwazi lomsebenzisi.

8. Ukucatshangelwa kokulawula:

I-Carbomer: I-Carbomers ngokuvamile yamukelwa njengephephile (GRAS) ngabaphathi abalawulayo lapho isetshenziswa ngokuya ngezindlela ezinhle zokukhiqiza (GMP). Kodwa-ke, izidingo ezithile zokulawula zingahluka ngokuya ngesicelo esihlosiwe kanye nesifunda sendawo.

IHydroxYethylcellose: I-HydroxyEthylcellosi ibuye ibunjwe iphephile ukuze isetshenziswe kwezimonyo kanye nemithi yemithi, ngezimvume zokulawula ezivela kubaphathi abafanele. Ukuhambisana nemigomo nemihlahlandlela esebenzayo kubalulekile ekuqinisekiseni ukuphepha komkhiqizo kanye nokusebenza kahle.

Ngenkathi bobabili i-carbomer kanye ne-hydroxyEtylcellosis besebenza njengezikhuthalo ezisebenzayo zokwakhiwa okuhlukahlukene, ziyehluka ngokuya ngokwakhiwa kwamakhemikhali, ukwakheka kwamangqamuzana, ukuhambisana, izindawo zohlelo lokusebenza, ukucatshangelwa kwemizwa, kanye nokucatshangelwa kwemizwa, kanye nokucatshangelwa kwemizwa, kanye nokucatshangelwa kokulawula. Ukuqonda lo mehluko kubalulekile ukuthi ama-amerota akhethe isithako esifaneleke kakhulu ngezidingo zabo zomkhiqizo nezinqubo zokusebenza.