I-HPMC (i-hydroxypropyl methylcellulose) iyi-ether engeyona ionic cellulose esetshenziswa kabanzi ekwakheni, emithini, ekudleni, kwamakhemikhali nsuku zonke nakwezinye izimboni. Ngokwendlela yayo yokuhlakazeka kanye nezici zohlelo lokusebenza, i-HPMC ingahlukaniswa ngezinhlobo ezimbili: uhlobo olusheshayo kanye nohlobo oluncibilikayo olushisayo. Kunomehluko omkhulu phakathi kwalokhu okubili ngokwenqubo yokukhiqiza, izimo zokuhlakazwa kanye nezimo zokusetshenziswa.
1. I-HPMC esheshayo
I-HPMC esheshayo, ebizwa nangokuthi uhlobo oluncibilikayo lwamanzi abandayo, ingancibilika ngokushesha emanzini abandayo ukuze yakhe isixazululo se-colloidal esisobala. Izici zayo eziyinhloko zimi kanje:
1.1. Ukuncibilika
I-Instant HPMC ibonisa ukuncibilika okuhle kakhulu emanzini abandayo futhi ihlakazeka ngokushesha lapho ichayeke emanzini. Ingancibilika ngesikhathi esifushane ukwenza isisombululo esifanayo, ngokuvamile ngaphandle kwesidingo sokushisa. Isixazululo saso esinamanzi sinokucaca okuhle, ukuzinza kanye namakhono okulungisa i-viscosity.
1.2. Izimo zohlelo lokusebenza
I-HPMC esheshayo isetshenziswa kakhulu ezimeni ezidinga ukuqedwa ngokushesha kanye nokwakhiwa kwesixazululo. Izindawo ezijwayelekile zohlelo lokusebenza zifaka:
Inkambu yokwakha: isetshenziswa njenge-ejenti egcina amanzi kanye ne-ejenti yokujiya ezintweni ezisekelwe kusimende nemikhiqizo yegypsum ukusiza ukuthuthukisa ukusebenza komsebenzi wokwakha.
Imikhiqizo yansuku zonke yamakhemikhali: njengezihlanzi, ama-shampoos, izimonyo, njll., i-HPMC esheshayo inganikeza imiphumela yokuqina nokumiswa kwemikhiqizo, futhi incibilika ngokushesha, iyenze ifanelekele izikhathi zokulungiselela ngokushesha.
Imboni yezemithi: Isetshenziswa njenge-ejenti yokwenza ifilimu, ingcina, njll. kumaphilisi. Ingaqedwa ngokushesha emanzini abandayo ukuze kube lula ukukhiqizwa kwamalungiselelo.
1.3. Izinzuzo
Incibilika ngokushesha futhi ifanele izimo zokucubungula ezibandayo.
Kulula ukufaka futhi ububanzi bokusebenzisa.
Isixazululo sinokucaca okuphezulu nokuzinza okuhle.
2. Hot ncibilika HPMC
I-Hot-melt HPMC, eyaziwa nangokuthi uhlobo oluncibilikayo emanzini ashisayo noma uhlobo lokuncibilika okulibele, kufanele incibilike ngokuphelele emanzini ashisayo, noma ingase idinge isikhathi eside sokuncibilika emanzini abandayo ukuze kancane kancane yakhe isisombululo. Izici zayo zimi kanje:
2.1. Ukuncibilika
Ukuziphatha kokuncibilika kwe-hot-melt HPMC kuhluke kakhulu kuleyo yohlobo olusheshayo. Emanzini abandayo, i-HPMC encibilikayo ihlakaza kuphela kodwa ayincibiliki. Izoncibilika kuphela futhi yakhe isixazululo lapho ishiselwa ezingeni lokushisa elithile (imvamisa lizungeze u-60°C). Uma ingezwe emanzini abandayo futhi inyakaziswa ngokuqhubekayo, i-HPMC izomunca kancane kancane amanzi futhi iqale ukuncibilika, kodwa inqubo ihamba kancane.
2.2. Izimo zohlelo lokusebenza
I-Hot-melt HPMC isetshenziswa kakhulu ezimeni lapho isikhathi sokuqedwa noma izimo ezithile zokucubungula okushisayo zidinga ukulawulwa. Izindawo ezijwayelekile zohlelo lokusebenza zifaka:
Izinto zokwakha: njengezinamatheliso zokwakha, izinsimbi zokunamathisela, njll., i-HPMC encibilika ngokushisayo ingabambezela ukuhlakazeka, inciphise ukuhlangana ngesikhathi sokuxutshwa noma ukunyakaziswa, futhi ithuthukise ukusebenza komsebenzi wokwakha.
Imboni yezemithi: Njengezinto zokumboza zamathebulethi akhishwa isikhathi eside, njll., i-HPMC encibilika ngokushisayo isiza ukulawula izinga lokukhishwa kwezidakamizwa ngezici zayo zokuncibilika kumazinga okushisa ahlukene.
Imboni yokumboza: isetshenziselwa ukufaka izicelo ngaphansi kwezimo ezithile ezikhethekile zokushisa okuphezulu ukuze kuqinisekiswe ukwakheka okuhle kwefilimu nokuzinza phakathi nenqubo yokwakha.
2.3. Izinzuzo
Ingabambezela ukuqedwa futhi ifanele izikhathi ezinezidingo ezikhethekile ngesivinini sokuhlakazeka.
Ivimbela i-agglomeration emanzini abandayo futhi inokusebenza okuhle kokuhlakazeka.
Ifanele ukucubungula okushisayo noma izinhlelo zokusebenza lapho ukulawulwa kwenqubo yokuchithwa kuyadingeka.
3. Umehluko omkhulu phakathi kohlobo olusheshayo nohlobo lwe-hot melt
3.1. Izindlela ezihlukene zokuqeda
I-HPMC esheshayo: Ingancibilika ngokushesha emanzini abandayo ukuze yakhe isixazululo esisobala, esisebenziseka kalula futhi esisheshayo.
I-Hot-Melt HPMC: Idinga ukuncibilika emanzini ashisayo noma idinga ukuncibilika ngokuphelele emanzini abandayo isikhathi eside, afanele izidingo ezithile zokulawula ukuncibilika.
3.2. Umehluko emikhakheni yohlelo lokusebenza
Ngenxa yezici zayo zokuqedwa ngokushesha, i-HPMC esheshayo ifanele izimo lapho isixazululo sidinga ukwakhiwa ngokushesha, njengokwakhiwa kanye nokulungiswa komkhiqizo wamakhemikhali wansuku zonke. I-HPMC ye-Hot-melt isetshenziswa kakhulu ezimeni lapho ukuchithwa okubambezelekile kudingwa khona, ikakhulukazi ezindaweni zokwakha ezinezinga lokushisa eliphezulu noma izindawo ezinezidingo eziqinile zesikhathi sokuqedwa.
3.3. Umehluko ohlelweni lomkhiqizo
Phakathi nenqubo yokukhiqiza, i-HPMC esheshayo iguqulwa ngamakhemikhali ukuze incibilike ngokushesha emanzini abandayo. I-Hot-melt HPMC igcina izakhiwo zayo zangempela futhi kufanele incibilikiswe emanzini ashisayo. Ngakho-ke, ezinhlelweni zokukhiqiza zangempela, kuyadingeka ukukhetha uhlobo olufanele lwe-HPMC ngokwemibandela yenqubo ehlukene kanye nezidingo zomkhiqizo.
4. Izinto okufanele uziqaphele lapho ukhetha i-HPMC
Lapho ukhetha ukusebenzisa i-HPMC esheshayo noma encibilikayo, udinga ukwenza isahlulelo esisuselwe kuzidingo ezithile zohlelo lokusebenza:
Ezimweni ezidinga ukuqedwa ngokushesha: njengezinto zokwakha ezidinga ukusetshenziswa ngokushesha ngesikhathi sokukhiqiza, noma imikhiqizo yansuku zonke yamakhemikhali elungiswa ngokushesha, i-HPMC ehlakazeka ngokushesha kufanele ikhethwe.
Ezimweni ezidinga ukulibaziseka kokuqedwa noma ukucutshungulwa kokushisa: okufana nosimende, ama-coatings, noma amaphilisi okukhishwa okuqhubekayo kwezidakamizwa adinga ukulawula izinga lokuhlakazeka phakathi nokwakhiwa, i-HPMC encibilikayo kufanele ikhethwe.
Kunomehluko osobala ekusebenzeni kokuqedwa nezinkambu zohlelo lokusebenza phakathi kwe-HPMC esheshayo ne-hot-melt HPMC. Uhlobo olusheshayo lufanele izinhlelo zokusebenza ezidinga ukuqedwa ngokushesha, kuyilapho uhlobo lwe-hot melt lufaneleka kakhulu izimo ezidinga ukuchithwa okulibazisekayo noma ukucutshungulwa kokushisa. Kuzinhlelo zokusebenza ezithile, ukukhetha uhlobo olufanele lwe-HPMC kungathuthukisa ukusebenza kahle kokukhiqiza futhi kuthuthukise ukusebenza komkhiqizo. Ngakho-ke, ekukhiqizeni nasekusetshenzisweni kwangempela, kuyadingeka ukukhetha ngokunengqondo uhlobo lwe-HPMC ngokusekelwe ezimweni ezithile zenqubo kanye nezidingo zomkhiqizo.
Isikhathi sokuthumela: Sep-25-2024