Yiliphi iphuzu lokuncibilika le-HPMC polymer?

I-HPMC (HYDROXYPROPYL Methylcellulose) Ikhompiyutha ene-polymer esetshenziswa ngamanzi esetshenziswa kabanzi eMkhemeni, ekudleni, ekwakheni, izimonyo kanye nezinye izimboni. I-HPMC iyi-celtulose ye-semi-sonthetic cellulose etholwe ukuguqulwa kwamakhemikhali kwe-cellulose yemvelo, futhi kuvame ukusetshenziswa njengesikhulu, i-stabilizer, emulsifier kanye nokunamathela.

Izakhiwo ezibonakalayo ze-HPMC

Iphoyinti lokuncibilika le-HPMC liyinkimbinkimbi ngokwengeziwe ngoba iphuzu laso lokuncibilika alibonakali njengelelo mpahla ye-crystalline ejwayelekile. Iphoyinti layo elincibilikayo lithintwa isakhiwo samangqamuzana, isisindo samangqamuzana kanye nezinga lokufaka esikhundleni se-hydroxypropyl kanye namaqembu we-methyl, ngakho-ke kungahluka ngokuya ngomkhiqizo othize we-HPMC. Ngokuvamile, njenge-polymer esolulekayo yamanzi, i-HPMC ayinayo indawo ecacile futhi evamile yokuncibilika, kepha ithambisa futhi ibophele ngaphakathi kwebanga lokushisa elithile.

Uhla lwe-Melling Point

Ukuziphatha okushisayo kweCefitchel®HPMC kuyinkimbinkimbi ngokwengeziwe, futhi ukusebenza kwawo okuwohloka okushisayo kuvame ukufundwa ukuhlaziywa kwe-thermogravimetric (TGA). Ezincwadini, kungatholakala ukuthi uhla lwendawo yokuncibilika ye-HPMC icishe ibe phakathi kwama-200°C no-300°C, kepha leli banga alimeleli iphuzu langempela lokuncibilika layo yonke imikhiqizo ye-HPMC. Different types of HPMC products may have different melting points and thermal stability due to factors such as molecular weight, degree of ethoxylation (degree of substitution), degree of hydroxypropylation (degree of substitution).

Isisindo esiphansi se-molecular HPMC: Imvamisa iyancibilika noma ithambisa emazingeni okushisa aphansi, futhi ingaqala nge-prolyze noma incibilike ngabo-200°C.

Isisindo esiphakeme se-molecular HPMC°C no-300°C.

Izici ezithinta iphuzu le-HPMC

Isisindo samangqamuzana: Isisindo se-molecular se-HPMC sinomthelela omkhulu endaweni yaso yokuncibilika. Isisindo se-molecular esiphansi sivame ukusho izinga lokushisa eliphansi, ngenkathi isisindo esiphakeme samangqamuzana singaholela endaweni ephakeme yokuncibilika.

I-degree yokufaka esikhundleni se-hydroxypropylication (okusho ukuthi isilinganiso sokufakwa kwe-hydroxypropyl ku-molecule) kanye degree of methylule) kanye degree of methylule) kanye degree of methylule) kanye degree of methylule) kanye degree of methylule) kanye degree of methylule) kanye degree of methylule) kanye degree of methylule) kanye degree of methylation (okungukuthi isikhundla sokufakwa esikhundleni se-methyl) i-hpmc ne-methmc nayo ithinta iphuzu layo lokuncibilika nalo lithinta iphuzu layo lokuncibilika. Ngokuvamile, izinga eliphakeme lokufaka esikhundleni senyuka sokulula kwe-HPMC futhi linciphise iphuzu laso lokuncibilika.

Okuqukethwe umswakama: Njengezinto ezingena emanzini, iphuzu le-HPMC libuye lithintwe ngumswakama walo. I-HPMC enokuqukethwe komswakama okuphezulu ingahle ikhishwe nge-hydration noma ukuchithwa okuyingxenye, okuholela ekushintsheni kokushisa okuvumayo okushisayo.

Ukuqina okushisayo kanye nokushisa okuvumayo kwe-hpmc

Yize i-HPMC ayinayo iphuzu eliqinile lokuncibilika, ukuqina kwalo okushisayo kuyinkomba yokusebenza esemqoka. Ngokusho kwedatha ye-thermogravimetric (TGA), i-HPMC imvamisa iqala ukubola kuhlu lokushisa lwama-250°C kuya ku-300°C. Ukushisa okuvumayo okucacisiwe kuya ngesisindo samangqamuzana, izinga lokufaka esikhundleni kanye nezinye izakhiwo zomzimba nezamakhemikhali ze-HPMC.

Ukwelashwa okushisayo kuzinhlelo zokusebenza ze-HPMC

Kuzinhlelo zokusebenza, iphoyinti lokuncibilika kanye nokuqina okushisayo kwe-HPMC kubaluleke kakhulu. Isibonelo, embonini yezemithi, i-HPMC ivame ukusetshenziswa njengezinto ezibonakalayo zamakhompiyutha, izimbobo zefilimu, kanye nezithwali zezidakamizwa ezisetshenziselwa okuqhubekayo. Kulezi zicelo, ukuqina okushisayo kwe-HPMC kudinga ukufeza izidingo zokushisa zokutshala, ngakho-ke ukuqonda indlela yokuziphatha eshisayo kanye nobubanzi bendawo yokuncibilika ye-HPMC kubalulekile ukulawula inqubo yokukhiqiza.

Ensimini yokwakha, iCuncicchel®HPMC imvamisa isetshenziswa njengomuntu omkhulu odongeni olomile, ukumboza kanye nokunamathela. Kulezi zicelo, ukuqina okushisayo kwe-HPMC nakho kudinga ukuba phakathi kwebanga elithile ukuqinisekisa ukuthi akuboli ngesikhathi sokwakha.

I-HPMC, njengezinto ezibonakalayo ze-polymer, ayinayo indawo yokuncibilika ehleliwe, kepha kukhombisa ukuthambisa nezimpawu ze-pyrolysis ngaphakathi kwebanga elithile lokushisa. Uhla lwamaphoyinti wayo ngokuncibilika ngokuvamile phakathi kwama-200°C no-300°C, nephuzu elithile lokuncibilika lincike ezintweni ezinjengesisindo se-molecular, degree of hydroxypropylation, degree methylation, kanye nomswakama we-HPMC. Kulezi zimo ezihlukile zohlelo lokusebenza, ukuqonda lezi zinto ezishisayo kubalulekile ukuze kulungiswe futhi kusetshenziswe.